| Concept Support & Accommodation Ltd | Public administration | 2026 |
| Concrete Designs Limited | Professional & scientific | 2018 |
| Concrete LEG Solutions Ltd | Construction | 2021 |
| Conference Space Limited | Administrative & support | 2023 |
| Connie Couriers Ltd | Transport & logistics | 2013 |
| Consumer Space Ltd | Real estate | 2019 |
| Cordwainer Cottage Ltd | Wholesale & retail | 2022 |
| Core Connect Group Limited | Financial services | 2024 |
| Core Connect Utilities Ltd | Construction | 2023 |
| Core Events Hospitality Group Ltd | Administrative & support | 2022 |
| Core Luxury Escapes Ltd | Administrative & support | 2025 |
| Cornerstone Investments (JR) Limited | Financial services | 2024 |
| Cornerstones Property Development Ltd | Real estate | 2020 |
| Cornford Consultancy Ltd | Professional & scientific | 2005 |
| Cornford Developments Limited | Real estate | 2004 |
| Cornford Lettings Limited | Real estate | 2005 |
| Corolus Ltd | Information & communication | 1999 |
| Cotes Park Holdings Limited | Transport & logistics | 2016 |
| County Packaging Services Limited | Manufacturing | 2001 |
| COX Law Limited | Professional & scientific | 2024 |
| Cpted UK Ltd | Administrative & support | 2024 |
| Cpted-Uk Ltd | Administrative & support | 2019 |
| Craft Wood Community Interest Company | Agriculture & fishing | 2018 |
| CRC Sales Ltd | Wholesale & retail | 2015 |
| Creative Connections (East Midlands) Ltd | Education | 2024 |
| Croft Rentals Ltd | Real estate | 2026 |
| Crofts Property Holdings Limited | Real estate | 2017 |
| Croi Diagnostics Limited | Health & social care | 2024 |
| Crossbow Printables Ltd | Wholesale & retail | 2019 |
| Crystal Dinner Limited | Hospitality | 2025 |
| Cs(Midlands) Limited | Wholesale & retail | 2014 |
| CSE Chatterbox Limited | Administrative & support | 2022 |
| CSE Ltd | Extraterritorial | 2022 |
| Csem Technologies Limited | Manufacturing | 2009 |
| CSG Furniture Limited | Wholesale & retail | 2023 |
| Cuddles-A-Plenty Limited | Other services | 2015 |
| CUK Way Ltd | Professional & scientific | 2022 |
| Curb Side Kitchen Limited | Hospitality | 2025 |
| Current Solutions (Midlands) Ltd | Construction | 2017 |
| Curve Digital Limited | Manufacturing | 2005 |
| CVN Trading Ltd | Wholesale & retail | 2026 |
| Czapp Property Ltd | Real estate | 2020 |
| D & D Vehicle Services Limited | Wholesale & retail | 2006 |
| D a Events Ltd | Arts & recreation | 2024 |
| D L a Property Developments Limited | Construction | 2025 |
| D S & P Services Limited | Manufacturing | 2000 |
| D&3R Buying and Selling of Own Real Estate Ltd | Real estate | 2024 |
| D&I Jaques Fruits Ltd | Hospitality | 2011 |
| D.B.I. Plant (Repair & Service) Limited | Manufacturing | 2009 |
| D.E.H. Barbers Ltd | Other services | 2019 |
| D.F. Wakefield Estates Limited | Real estate | 1986 |
| D.J. Ferret Limited | Arts & recreation | 2007 |
| DA Plant Repairs Limited | Manufacturing | 2012 |
| DAB Flooring NG10 Ltd | Construction | 2023 |
| DAN Kelly Windows & Doors Ltd | Construction | 2013 |
| DAN PT Fitness Limited | Other services | 2018 |
| Dancewear International Limited | Extraterritorial | 2020 |
| Daniel Jarmolinski Limited | Construction | 2018 |
| Danneva Ltd | Professional & scientific | 2013 |
| Darley Dale Construction Services Ltd | Construction | 2014 |
| Darley Dale Developments Ltd | Real estate | 2014 |
| Data Engineering and Ecommerce Consultants Limited | Information & communication | 2023 |
| Dave Massey Services Ltd | Education | 2024 |
| Dave Meakin Transport (Driver Hire) Ltd | Transport & logistics | 2020 |
| Daves Deliveryservices Ltd | Transport & logistics | 2024 |
| David Ashley Construction Limited | Construction | 2002 |
| David Ashley Developments Limited | Construction | 1995 |
| David Inglis Ltd | Construction | 2014 |
| David Nieper Holdings Limited | Financial services | 2019 |
| David Nieper Limited | Manufacturing | 1961 |
| David Rogers Limited | Administrative & support | 1964 |
| Davis Clarke Ltd | Administrative & support | 2023 |
| Dawson & Pedley Limited | Wholesale & retail | 2021 |
| Days of Currys Ltd | Hospitality | 2024 |
| Daytona Land Development Ltd | Households | 2025 |
| Dazza & Co Ltd | Information & communication | 2014 |
| DB Wise Limited | Information & communication | 2026 |
| DBA Properties and Lettings Limited | Real estate | 2023 |
| Deadwood Holdings Limited | Financial services | 2026 |
| Deal Opportunities Limited | Information & communication | 2013 |
| Deeplas Building Plastics Limited | Extraterritorial | 2009 |
| Deeplas Limited | Extraterritorial | 2009 |
| Deflect and Protect CIC | Education | 2024 |
| Deniz Yavuz Ltd | Hospitality | 2024 |
| Dennis RYE Limited | Construction | 1976 |
| Denture Solutions Ltd | Health & social care | 2025 |
| Derby Rail Consult Ltd | Professional & scientific | 2025 |
| Derbyshire Academy of Performing Arts Limited | Arts & recreation | 2024 |
| Derbyshire Academy of Performing Arts Show Company Limited | Arts & recreation | 2026 |
| Derbyshire Antiques & Interiors Ltd | Wholesale & retail | 2020 |
| Derbyshire Brickwork Limited | Construction | 2005 |
| Derbyshire CE Inns Limited | Hospitality | 2018 |
| Derbyshire Centre for Renewable Energy Limited | Information & communication | 2021 |
| Derbyshire Equestrian Ltd | Construction | 2026 |
| Derbyshire GAS Geeks Ltd | Extraterritorial | 2021 |
| Derbyshire Mortgages & Protection Limited | Financial services | 2020 |
| Derbyshire Web Hosting Limited | Information & communication | 2014 |
| Derbyshire Wills Limited | Professional & scientific | 2017 |
| Derwent Beds Limited | Manufacturing | 2016 |
| Derwent Decorating Services Limited | Construction | 2009 |