| Simple Lottery Ltd | Extraterritorial | 2007 |
| Simply Electric Gates (Services) Limited | Construction | 2015 |
| Simply Servicing Ltd | Wholesale & retail | 2021 |
| Sina Care Lodge Limited | Health & social care | 2021 |
| Singh Maintenance Ltd | Construction | 2024 |
| Sinibila Ltd | Wholesale & retail | 2025 |
| Siskin Gold Ltd | Manufacturing | 2026 |
| Sisters Collection Ltd | Wholesale & retail | 2025 |
| Sisters Jewellers Limited | Wholesale & retail | 2025 |
| Sital-Pati News Ltd | Information & communication | 2024 |
| Siteline Properties Limited | Real estate | 2021 |
| Siteline Property Managment Ltd | Construction | 2017 |
| Sixth Avondale Residents Association Limited(The) | Households | 1985 |
| SJ Designstudio Ltd | Professional & scientific | 2019 |
| SJ Rose Electrical Limited | Construction | 2009 |
| SJE Capital Limited | Information & communication | 2024 |
| SKA Telecoms Ltd | Information & communication | 2014 |
| SKF Logistics Limited | Transport & logistics | 2021 |
| Skin Lounge Surrey Ltd | Other services | 2026 |
| Skrnrs Property Group Limited | Real estate | 2025 |
| Sky 20 Ltd | Wholesale & retail | 2024 |
| Skyco Limited | Wholesale & retail | 2009 |
| SL Baker Properties Ltd | Households | 2024 |
| SLJ Legal Services Ltd | Professional & scientific | 2020 |
| Slowhorse Ltd. | Information & communication | 2012 |
| Slush Media Limited | Information & communication | 2003 |
| Smash N DIP Ltd | Hospitality | 2025 |
| Smhq Capital Limited | Transport & logistics | 2020 |
| Smhq Limited | Construction | 2020 |
| Smile IT Limited | Information & communication | 2005 |
| Smoother Removals Ltd | Transport & logistics | 2025 |
| SMP Corporate Ltd | Other services | 2026 |
| SMP Couk Ltd | Other services | 2025 |
| SMS Coffee Ltd | Hospitality | 2016 |
| SN7 Properties Limited | Real estate | 2024 |
| Snack Society Limited | Wholesale & retail | 2025 |
| SNB47 Limited | Professional & scientific | 2024 |
| SNS Heritage Limited | Real estate | 2025 |
| Snug Creative Hub Ltd | Arts & recreation | 2025 |
| Snug Spaces Ltd | Real estate | 2023 |
| SNW Ltd | Hospitality | 2018 |
| SO Smart Engineering Limited | Administrative & support | 2011 |
| Sober Mama Ltd | Other services | 2022 |
| Sofrom Limited | Construction | 2022 |
| Soft Touch Refinishing Solutions Limited | Manufacturing | 2025 |
| Softwise Ltd | Information & communication | 2019 |
| Solak Care Ltd | Health & social care | 2022 |
| Solin Natural Skincare Ltd | Wholesale & retail | 2025 |
| Solus Exchange Ltd | Information & communication | 2024 |
| Solution HUT Limited | Wholesale & retail | 2008 |
| Solutions Security Ltd | Administrative & support | 2020 |
| Solve Planning Limited | Professional & scientific | 2011 |
| Sonal Properties Ltd | Real estate | 2025 |
| Sonatee Ltd | Hospitality | 2025 |
| Sonogrl Limited | Health & social care | 2018 |
| Soul by Auction Limited | Wholesale & retail | 2009 |
| Soulmine Limited | Wholesale & retail | 2005 |
| Sound & Vision Facilities Ltd | Other services | 2011 |
| Sound and Motion Studios Ltd | Manufacturing | 2026 |
| South Asia Flavour Limited | Wholesale & retail | 2020 |
| South Coast Elite Brands Ltd | Wholesale & retail | 2023 |
| South Downs Roastery Limited | Manufacturing | 2023 |
| Southdown Landscapes Limited | Administrative & support | 2023 |
| Southern Counties Electric Ltd | Construction | 2019 |
| Southern Enterprise Alliance | Administrative & support | 2001 |
| Southern Fire Door Services Ltd | Professional & scientific | 2022 |
| Southway Roofing Ltd | Construction | 2024 |
| Southwood Heating Solutions Limited | Construction | 2008 |
| Sovereign Shelter Estates Ltd | Real estate | 2024 |
| SP Installations Ltd | Construction | 2005 |
| Sparkle Leads UK Ltd | Manufacturing | 2026 |
| SPE Tech Ltd | Wholesale & retail | 2020 |
| Specialised Metal Fabrications Ltd | Manufacturing | 2015 |
| Specialist Maintenance Service Ltd | Professional & scientific | 2022 |
| Spedeworth Fabrications 2015 Ltd | Manufacturing | 2015 |
| Spedeworth International (East Anglia) Ltd | Arts & recreation | 2002 |
| Spedeworth International (Southern) Ltd | Arts & recreation | 2002 |
| Spedeworth Motorsports Ltd | Extraterritorial | 2012 |
| Speedway Designs Limited | Information & communication | 2008 |
| Spencer Yaso Designs Limited | Professional & scientific | 2023 |
| Spices of India Ltd | Hospitality | 2024 |
| Spiro Creatives Ltd | Information & communication | 2025 |
| Sports Progression Hub Ltd | Education | 2026 |
| Spresso FIX Ltd | Manufacturing | 2025 |
| Springmead Personnel Ltd | Health & social care | 2016 |
| SPW Stones Pressure Washing Limited | Administrative & support | 2025 |
| SR & LB Ltd | Hospitality | 2018 |
| SRB Plumbing & Heating Limited | Construction | 2013 |
| Srsa Ltd | Transport & logistics | 2019 |
| SS Proclean Ltd | Administrative & support | 2025 |
| Ssam Group Limited | Construction | 2025 |
| SSR Limited | Manufacturing | 2000 |
| Ssua Foods Ltd | Hospitality | 2025 |
| SSV Venture Group Limited | Hospitality | 2024 |
| ST Fast FIX Limited | Construction | 2025 |
| Stack Scaffolding Ltd | Construction | 2020 |
| Stagg Carpentry Ltd | Construction | 2026 |
| Stainless Bar Sales Limited | Professional & scientific | 2000 |
| Stainless Steel Reinforcement Limited | Wholesale & retail | 2007 |
| Stair Edge Ltd | Construction | 2026 |