| Flemingate Accountancy and Taxation Limited | Professional & scientific | 2013 |
| Flex Fibre Limited | Extraterritorial | 2015 |
| Flexible Mind Psychology Ltd | Health & social care | 2021 |
| Flig Ltd | Real estate | 2022 |
| Flight Over Yorkshire Limited | Arts & recreation | 2024 |
| Flights & Wires Ltd | Professional & scientific | 2025 |
| Fling Agency Ltd | Professional & scientific | 2026 |
| Flinnie Developments Limited | Construction | 2018 |
| Flint Grange (Clacton) Residents Management Company Limited | Households | 2020 |
| Flintplain Limited | Real estate | 1988 |
| Flintwood & Associates Limited | Professional & scientific | 2024 |
| FLO & Co Interiors Ltd | Construction | 2017 |
| Flo-Aktiv Limited | Professional & scientific | 2013 |
| Flo-Rite Draincare Ltd | Water & waste | 2025 |
| Flochem Limited | Manufacturing | 1993 |
| Flock of Sea Birds Limited | Hospitality | 2026 |
| Flockdale Limited | | 1992 |
| Flocoe Interiors Ltd | Construction | 2019 |
| Floks Home Ltd | Wholesale & retail | 2021 |
| Flood Divert Limited | Construction | 2012 |
| Flora Aesthetics Ltd | Health & social care | 2024 |
| Floral Elegance (Acomb) Ltd | Wholesale & retail | 2008 |
| Floralibus Limited | Wholesale & retail | 2024 |
| Florenewables Limited | Professional & scientific | 2014 |
| Florent Court Management Ltd | Real estate | 2004 |
| Florian Poirot Ltd. | Hospitality | 2019 |
| Florina 221 Healthcare Ltd | Health & social care | 2020 |
| Flosal Marketing Limited | Other services | 2025 |
| Flourish Property Ltd | Real estate | 2018 |
| Flourish York Limited | Hospitality | 2026 |
| Flow Book Ltd | Extraterritorial | 2014 |
| Flower Duet Ltd | Financial services | 2026 |
| Flowkind Ltd | Manufacturing | 2026 |
| Flowmotion Ltd | Information & communication | 2020 |
| Flowvate Consulting Ltd | Professional & scientific | 2026 |
| Fluechem Holdings Ltd | Financial services | 2022 |
| Fluechem Ltd | Manufacturing | 2019 |
| Fluid Fusion Ltd | Administrative & support | 2009 |
| Fluidcorp Ltd | Real estate | 2016 |
| Flux Therapy Limited | Health & social care | 2025 |
| FLY Hire Limited | Arts & recreation | 2004 |
| FLY Signs Limited | Manufacturing | 2015 |
| Flyby Drones Limited | Extraterritorial | 2020 |
| Flyby Technology Limited | Extraterritorial | 2020 |
| Flyby Technology Turkey Ltd | Education | 2021 |
| Flyby USA Limited | Extraterritorial | 2020 |
| Flyer TV Ltd | Professional & scientific | 2023 |
| Flying Cloud Theatre | Education | 2012 |
| Flying Dragon York Limited | Hospitality | 2024 |
| Flying Ducks Trampoline Club Ltd | Education | 2019 |
| Fm&D Transport Ltd | Transport & logistics | 2017 |
| FME Waste Management and Removals Ltd | Water & waste | 2025 |
| FNP Services Group Ltd | Financial services | 2020 |
| Foam Sheds and Igloos Limited | Construction | 2024 |
| Focarelli's Shoe & Leather Restorations Ltd | Wholesale & retail | 2022 |
| Focus 4 Print Limited | Manufacturing | 2008 |
| Focus Energy Services Limited | Professional & scientific | 2021 |
| Focus Energy Solutions Ltd | Information & communication | 2026 |
| Focus Fireplaces (Manufacturing) Limited | Manufacturing | 2015 |
| Focus Fireplaces (Showroom) Limited | Wholesale & retail | 2015 |
| Focus Point Talent Ltd | Administrative & support | 2026 |
| Focusing Events Limited | Administrative & support | 2017 |
| Focusing Pursuits Ltd | Extraterritorial | 2015 |
| FOD Holdings Ltd | Real estate | 2025 |
| Fodda Ltd | Information & communication | 2021 |
| Foghorn Digital Ltd | Information & communication | 2025 |
| Folkbox Limited | Arts & recreation | 2024 |
| Follow Your Arrow Ltd | Professional & scientific | 2024 |
| Fond Food Limited | Hospitality | 2024 |
| Fonefix Limited | Manufacturing | 1988 |
| Food 2 Remember (Yorkshire) Ltd | Wholesale & retail | 2013 |
| Food and Health Communications Limited | Health & social care | 2002 |
| Food Circle York CIC | Manufacturing | 2017 |
| Food Cottage Limited | Hospitality | 2022 |
| Food Prep Shop Ltd | Hospitality | 2022 |
| Food Process Technology Ltd | Manufacturing | 2023 |
| Food Quality & Consulting Ltd | Manufacturing | 2025 |
| Food Station 56 Ltd | Hospitality | 2024 |
| Foodnoise Ltd | Professional & scientific | 2025 |
| Foolish Pursuits Limited | Financial services | 2024 |
| Football FUN Factory (Community 062) Limited | Arts & recreation | 2022 |
| Football Tots Ltd | Education | 2019 |
| Football Travelher Ltd | Administrative & support | 2025 |
| FOR Locks That Break Ltd | Other services | 2025 |
| FOR YOO Ltd | Information & communication | 2006 |
| Forbidden Forest Ltd | Wholesale & retail | 2024 |
| Forces Transition Group Limited | Administrative & support | 2023 |
| Ford Water Limited | Construction | 2019 |
| Forensic Voice Centre Limited | Professional & scientific | 2023 |
| Foresight Nexus Global Ltd | Professional & scientific | 2025 |
| Foresite Consulting Limited | Construction | 2023 |
| Forest Farm (Poultry) Limited | Real estate | 2018 |
| Forest Gate House Limited | Households | 2002 |
| Forest Group Ltd. | Hospitality | 2019 |
| Forest IT Services Limited | Information & communication | 2004 |
| Forest Lane Cafe Ltd | Hospitality | 2025 |
| Forest Lane Construction Ltd | Construction | 2020 |
| Forest Lane Electrical Services Ltd | Manufacturing | 2021 |
| Forest of Galtres Care Limited | Health & social care | 2026 |
| Forest Park Golf Club Limited | Construction | 1989 |