| Your Virtual Assistant (York) Limited | Administrative & support | 2021 |
| Your Yorkshire Surveyors Limited | Professional & scientific | 2024 |
| Yourcafe York CIC | Hospitality | 2018 |
| Yourclad Ltd | Construction | 2026 |
| Ypbc Limited | Financial services | 2023 |
| YPC (York) Ltd | Manufacturing | 2025 |
| YRG Corrugated Limited | Extraterritorial | 2021 |
| YRG Eclipse Limited | Manufacturing | 1982 |
| YRG Group Limited | Manufacturing | 1997 |
| YRG Properties Limited | Real estate | 2016 |
| YRG Sleeves Limited | Extraterritorial | 2005 |
| YRG Solutions Limited | Manufacturing | 2004 |
| YRK Football Group Ltd | Arts & recreation | 2025 |
| YRK House Limited | Health & social care | 2025 |
| YRK Nursery Limited | Health & social care | 2026 |
| YRK Property Limited | Real estate | 2026 |
| YRK Windows Ltd | Construction | 2019 |
| YSJ Innovations Ltd | Information & communication | 2025 |
| YSS Solutions Limited | Construction | 2016 |
| YST Limited | Professional & scientific | 2013 |
| YT Records Ltd | Information & communication | 2016 |
| YT Social CIC | Information & communication | 2020 |
| Yuja Limited | Professional & scientific | 2018 |
| Yumi Grill House Limited | Health & social care | 2020 |
| Yumi House Group Ltd | Hospitality | 2026 |
| Yummi Limited | Hospitality | 2015 |
| Yummy HO Ltd | Hospitality | 2024 |
| Yummycomb Ltd | Manufacturing | 2018 |
| Yunsa UK Limited | Other services | 2007 |
| Yusu Commercial Services Limited | Other services | 2009 |
| Yuzu Street Food Ltd | Hospitality | 2021 |
| Yves Creations Ltd | Wholesale & retail | 2025 |
| Yvonne & Jael Global Enterprises Limited | Extraterritorial | 2021 |
| Yvonne’S Childcare Services Limited | Health & social care | 2022 |
| YÖ Holdings Limited | Financial services | 2026 |
| Z-Breeze Limited | Administrative & support | 2025 |
| ZAC Planning & Management Services Ltd | Professional & scientific | 2026 |
| Zahir's Limited | Hospitality | 2025 |
| Zamzam Foods York Ltd | Wholesale & retail | 2019 |
| Zanet Interiors Ltd | Construction | 2025 |
| Zanft Labs Ltd | Information & communication | 2025 |
| Zara Silversmith Ltd | Arts & recreation | 2022 |
| ZAZ Medics Ltd | Real estate | 2022 |
| Zazzapples Ltd | Real estate | 2025 |
| ZCS Property Limited | Construction | 2019 |
| ZE HE Ltd | Households | 2023 |
| Ze-Au Ltd | Wholesale & retail | 2026 |
| Zebraflow Ltd | Information & communication | 2023 |
| ZEE Success Solutions Ltd | Wholesale & retail | 2025 |
| Zeeks - Art for Geeks Ltd | Professional & scientific | 2022 |
| ZEH Ltd | Administrative & support | 2024 |
| Zelden Co Ltd | Professional & scientific | 2021 |
| Zellol Power Holdings Ltd | Wholesale & retail | 2022 |
| ZEN Accommodation Limited | Real estate | 2025 |
| ZEN Dog Consulting Limited | Professional & scientific | 2018 |
| ZEN Living Spaces Ltd | Real estate | 2025 |
| ZEN Moose Limited | Professional & scientific | 2007 |
| Zendo Technologies Limited | Information & communication | 2025 |
| Zenest Ltd | Wholesale & retail | 2026 |
| Zenguard Therapeutics Limited | Wholesale & retail | 2023 |
| Zenith Traders Limited | Wholesale & retail | 2014 |
| Zenox Autos Ltd | Wholesale & retail | 2026 |
| Zenti Digital Ltd | Professional & scientific | 2025 |
| Zero Hours Justice Ltd | Information & communication | 2020 |
| Zerooba Solutions Ltd | Professional & scientific | 2020 |
| Zest (Newton Heath) Management Company Limited | Households | 2011 |
| Zest (Swainby) Ltd | Administrative & support | 2011 |
| Zest Apartments (Newton Heath) Management Company Limited | Households | 2012 |
| Zest Consult Ltd | Information & communication | 2020 |
| Zesty Enterprise Ltd | Information & communication | 2024 |
| Zeta Wealth Ltd | Information & communication | 2022 |
| ZFO York Ltd | Real estate | 2025 |
| Zhina Holdings Ltd | Real estate | 2021 |
| Ziggy & Friends Dog Grooming Ltd | Wholesale & retail | 2020 |
| Ziggy's Limited | Real estate | 1998 |
| Ziggy's Nightclub Limited | Hospitality | 2020 |
| Ziko Shawarma Ltd | Hospitality | 2025 |
| Zimo Property Limited | Real estate | 2023 |
| Zinc Electrical Ltd | Construction | 2024 |
| Zinc Property Limited | Real estate | 2016 |
| Zinnabar Ltd | Information & communication | 2018 |
| Zintegrity Limited | Professional & scientific | 2023 |
| Zipcrown Limited | Real estate | 1977 |
| Zirkonzahn Britannica Ltd | Manufacturing | 2021 |
| Zisco Courier Ltd | Transport & logistics | 2023 |
| Zissler Property Limited | Real estate | 2019 |
| ZK Performance Ltd | Manufacturing | 2020 |
| Zoom Courier Services Ltd | Transport & logistics | 2024 |
| Zoranovich Limited | Wholesale & retail | 2025 |
| Zulugolf Properties Ltd | Real estate | 2026 |
| Zure Solutions UK Limited | Administrative & support | 2024 |
| Zuri Photography Ltd | Professional & scientific | 2021 |
| Zuruk Global Health Ltd | Health & social care | 2025 |