| PT Composites Ltd | Manufacturing | 2025 |
| Public Policy Consultants Ltd | Professional & scientific | 2018 |
| Puckett’S Pickles Ltd | Manufacturing | 2017 |
| Puddleducks Children's Day Nursery Holdings Ltd | Real estate | 2024 |
| Puddleducks Children's Day Nursery Ltd | Health & social care | 2016 |
| Puddleducks Children's Day Nursery Malton Ltd | Health & social care | 2021 |
| Puddleducks Children's Day Nursery Pickering Ltd | Health & social care | 2024 |
| PUE Limited | Manufacturing | 2026 |
| Pulleyn Investments Limited | Construction | 2014 |
| Pulleyn Retail Limited | Wholesale & retail | 2015 |
| Pumpcon Ltd | Construction | 2022 |
| Pumpline Ltd | Construction | 2017 |
| Punchbag Limited | Extraterritorial | 2022 |
| Puntale Holdings Ltd | Real estate | 2002 |
| PUR Cattery Limited | Other services | 2025 |
| Pura Salutem Limited | Health & social care | 2018 |
| Purdy's Plumbing & Heating Ltd | Construction | 2018 |
| Pure Auto Design Limited | Extraterritorial | 2012 |
| Pure Country M&Df Ltd | Arts & recreation | 2024 |
| Pure Green Roofing & Solar Limited | Construction | 2023 |
| Pure Green Scaffolding Limited | Construction | 2025 |
| Pure Touch York Ltd | Administrative & support | 2025 |
| Purelis Limited | Health & social care | 2018 |
| Purely Financial Limited | Financial services | 2015 |
| Purely Holistic Ltd | Wholesale & retail | 2024 |
| Purely Holistic Supplements, Ltd | Wholesale & retail | 2024 |
| Purenet Solutions Limited | Information & communication | 2006 |
| Purey Cust (York) Estate Limited | Real estate | 2015 |
| Purey Cust 2017 Management Company Limited | Households | 2017 |
| Purityhut Limited | Wholesale & retail | 2020 |
| Purple Chilli Events Catering Limited | Hospitality | 2012 |
| Purple JEM Ltd | Professional & scientific | 2025 |
| Purple Potato Software Limited | Information & communication | 2018 |
| Purpose Over Party Ltd | Other services | 2025 |
| Purstruct Ltd | Construction | 2023 |
| Pursuit Vision Limited | Information & communication | 2007 |
| PUT the Kettle on Ltd | Real estate | 2020 |
| Puzzle X Ltd | Arts & recreation | 2025 |
| PVG (Cardiff) Tradeco Ltd | Extraterritorial | 2018 |
| PVW ND Diagnostics Ltd | Health & social care | 2026 |
| PW Property (York) Limited | Real estate | 2018 |
| PWD Creative Ltd | Professional & scientific | 2013 |
| PWM Platforms Limited | Other services | 2022 |
| PWM Property Company Ltd | Real estate | 2024 |
| PWS Technical Services (UK) Ltd | Construction | 2011 |
| Pxld Labs Ltd | Information & communication | 2026 |
| PXY Reformer Pilates Limited | Health & social care | 2024 |
| Pycroft Property Management Ltd | Real estate | 2021 |
| Pygott & Crone Lincoln Lettings Limited | Real estate | 2018 |
| Pypa Limited | Information & communication | 2025 |
| Pyper York Limited | Professional & scientific | 2012 |
| Pyramid Estate Management Limited | Professional & scientific | 2004 |
| Pyrogen IP Limited | Extraterritorial | 2017 |
| Pysbury Walk Management Company Limited | Households | 2004 |
| Q York | Other services | 2006 |
| Q York Trading Limited | Real estate | 2025 |
| Q&K Auditors Ltd | Professional & scientific | 2003 |
| Q1 Industrial Limited | Professional & scientific | 2021 |
| QC Medica LLP | | 2018 |
| QD Logistics BV Ltd | Information & communication | 2009 |
| Qdeveloping Limited | Manufacturing | 2016 |
| QED Advisory Limited | Professional & scientific | 2008 |
| QF Tractors Limited | Wholesale & retail | 2015 |
| QH RTM Company Limited | Households | 2016 |
| QOF Properties (York) Ltd | Real estate | 2024 |
| QOF Properties LLP | | 2021 |
| QRP York Ltd | Construction | 2021 |
| Quadra AV Furniture Limited | Other services | 2016 |
| Quadroplay UK Ltd | Wholesale & retail | 2011 |
| Qualia Limited | Professional & scientific | 2009 |
| Qualis Wealth Limited | Administrative & support | 2019 |
| Quality Beyond Beleaf Ltd | Wholesale & retail | 2023 |
| Quality Circle Limited | Hospitality | 2019 |
| Quality Electrical Supplies and Technology Limited | Construction | 1991 |
| Quality Engine Limited | Information & communication | 2011 |
| Quality Home Check Ltd | Professional & scientific | 2021 |
| Quality Stitches of York Limited | Other services | 2015 |
| Qualocity Ltd. | Professional & scientific | 2015 |
| Qualtek Electrical Safety Limited | Construction | 2012 |
| Qualtek Limited | Administrative & support | 2003 |
| Quansah DEE Ltd. | Professional & scientific | 2017 |
| Quantock Veterinary Hospital Limited | Professional & scientific | 2010 |
| Quantock View Management Company Limited | Households | 2019 |
| Quantum Estate Agency Limited | Real estate | 2007 |
| Quantum Motors Ltd | Wholesale & retail | 2026 |
| Quantum Physical Limited | Professional & scientific | 2013 |
| Quantum Properties (York) Ltd | Real estate | 2024 |
| Quantum Quotient Soft Ltd | Wholesale & retail | 2024 |
| Quantus Freelance Limited | Professional & scientific | 2017 |
| Quantus Strategic Excellence Limited | Wholesale & retail | 2014 |
| Quarry Veterinary Clinic Limited | Extraterritorial | 2011 |
| Quart Developments 1 Limited | Construction | 2023 |
| Quart Developments Limited | Construction | 2025 |
| Quarterbacking Limited | Professional & scientific | 2017 |
| Quartz Slab Company Limited | Manufacturing | 2020 |
| Quattro Autocare Holdings Ltd | Professional & scientific | 2023 |
| Quattro Autocare Limited | Wholesale & retail | 2014 |
| Quay One (Leeds) Management Company Limited | Real estate | 2006 |
| Queen Ethelburga's Classic Company Limited | Administrative & support | 1993 |
| Queen Ethelburga's College Limited | Education | 1991 |