| Studio Yume Limited | Professional & scientific | 2020 |
| Studley Roofing Limited | Construction | 2001 |
| Suffield Consultants Ltd | Professional & scientific | 2026 |
| Sugar and Bloom Ltd | Manufacturing | 2025 |
| Sugarloaf Enterprises Limited | Other services | 1999 |
| Summerhouse Flats (Yeovil) Management Limited | Households | 1995 |
| Summerhouse View Limited | Real estate | 2020 |
| Sumudu Limited | Health & social care | 2024 |
| Sundial Technical Services Ltd | Construction | 2012 |
| Supplementori Ltd | Professional & scientific | 2018 |
| Sure Care Direct Ltd | Health & social care | 2023 |
| Surestart Automotive Limited | Wholesale & retail | 2013 |
| Surfsmile Limited | Manufacturing | 2023 |
| Surfsmile Therapies C.I.C. | Arts & recreation | 2025 |
| Susan Down Associates Limited | Health & social care | 2014 |
| Susan's Oriental Kitchen Ltd | Hospitality | 2023 |
| Suss Brand Limited | Professional & scientific | 2024 |
| SW Autotech Ltd | Wholesale & retail | 2012 |
| SW Locksmiths (Somerset) Ltd | Manufacturing | 2026 |
| Swan OUT Limited | Hospitality | 2017 |
| Swans Nest Exminster Limited | Hospitality | 2019 |
| Sweet Smart Ltd | Hospitality | 2016 |
| Sweet, Treats and Bakes Ltd | Manufacturing | 2024 |
| Sweets and Stuff Limited | Wholesale & retail | 2025 |
| Swift Fire and Rescue Ltd | Public administration | 2021 |
| Switched on Electrical (South West) Limited | Construction | 2021 |
| SX Services (Essex) Limited | Construction | 2016 |
| Sycamore Process Engineering Limited | Manufacturing | 2005 |
| Syedaalam Ltd | Health & social care | 2022 |
| Symonds Garages Limited | Real estate | 1993 |
| Symonds Property Management LLP | | 2005 |
| T 2 Digital Limited | Construction | 2010 |
| T J Foot Limited | Agriculture & fishing | 2019 |
| T Russell Developments Limited | Construction | 2007 |
| T.K.Jeans & Sons Limited | Agriculture & fishing | 1956 |
| Tactical Surface Ltd | Administrative & support | 2025 |
| Taggart Business Services Ltd | Professional & scientific | 2026 |
| Tailoredtrendzuk Ltd | Wholesale & retail | 2025 |
| Take the Plunge Property Limited | Real estate | 2021 |
| Tamburino Limited | Hospitality | 2003 |
| Tang Properties Ltd | Real estate | 2020 |
| Tankard & Co. Accountants Limited | Professional & scientific | 2011 |
| Taplow Court (Torquay) Limited | Real estate | 1974 |
| Targetsim Limited | Extraterritorial | 2007 |
| Taslim Foods Limited | Hospitality | 2018 |
| Taste (South West) Limited | Hospitality | 2005 |
| Tastirich Limited | Manufacturing | 2026 |
| Tatenda Brympton Ltd | Real estate | 2024 |
| Tawanda Pharmaservices Ltd | Wholesale & retail | 2022 |
| Taylor & Co Financial Limited | Financial services | 2021 |
| Taylor Decoration & Renovation Ltd | Construction | 2023 |
| Taylor Heating Services Ltd | Construction | 2024 |
| Taylor Made Business Solutions Ltd | Professional & scientific | 2016 |
| Taylor Property Developments Group Limited | Construction | 2021 |
| Taylor Property Investment Group Ltd | Real estate | 2021 |
| TD Overseas Properties Limited | Real estate | 2026 |
| Tea Garden Letting Ltd | Real estate | 2024 |
| Teams Software Limited | Information & communication | 2024 |
| TECH116 Limited | Financial services | 2022 |
| Techbright Limited | Information & communication | 2018 |
| Technical Food Consultancy Ltd | Professional & scientific | 2014 |
| Techniclean Holdings Limited | Wholesale & retail | 2018 |
| Technology Geeks Limited | Wholesale & retail | 2012 |
| Tecscape Ltd | Extraterritorial | 2013 |
| Telli London Limited | Manufacturing | 2024 |
| Telstar House Management Company Ltd | Real estate | 2020 |
| Telstar Services (SW) Ltd | Extraterritorial | 2010 |
| TEM Construction Limited | Construction | 2019 |
| Terracrystals Limited | Wholesale & retail | 2013 |
| Terror Matta Ltd | Arts & recreation | 2023 |
| Testimony African Food Store Ltd | Hospitality | 2021 |
| TFH Financial Limited | Professional & scientific | 2025 |
| TFI Salcombe Limited | Hospitality | 2007 |
| TGB Enterprises Limited | Real estate | 1997 |
| Thaikoon Company Limited | Hospitality | 2024 |
| That's SO Digital Ltd | Professional & scientific | 2025 |
| THE 7 Academy Limited | Education | 2023 |
| THE Acorn Somerset Limited | Hospitality | 2023 |
| THE Apex Gill Ltd | Real estate | 2022 |
| THE Bakery West Camel Ltd | Wholesale & retail | 2015 |
| THE Barber Shop (Yeovil) Limited | Other services | 2023 |
| THE Barn at Cott Farm Limited | Real estate | 2018 |
| THE Barton Public House Limited | Hospitality | 2015 |
| THE Black Diet Ltd | Wholesale & retail | 2026 |
| THE Blue Boar Wiltshire Ltd | Hospitality | 2025 |
| THE Bread Drink LAB Limited | Manufacturing | 2019 |
| THE Carbon Credit Exchange Limited | Professional & scientific | 2023 |
| THE Cider Shack Ltd | Extraterritorial | 2016 |
| THE Cleaning Mentors Limited | Professional & scientific | 2025 |
| THE Cobb Arms Limited | Hospitality | 2017 |
| THE Cotswold Nursing Home Company Limited | Health & social care | 1997 |
| THE Cross Keys Wanborough Limited | Hospitality | 2025 |
| THE Depot Box Limited | Wholesale & retail | 2011 |
| THE Digital XX Ltd | Professional & scientific | 2021 |
| THE Envelope Design Company Ltd | Extraterritorial | 2007 |
| THE FAT PIG Co (UK) Ltd | Hospitality | 2007 |
| THE Firefly Gift Store Ltd | Wholesale & retail | 2025 |
| THE Fireplace and Stove Centre Limited | Wholesale & retail | 2014 |
| THE Fountain Church | Other services | 2018 |
| THE Glanvilles Stud Limited | Agriculture & fishing | 2012 |