| Riverside Feeds Limited | Manufacturing | 1996 |
| RJ & DR Gingell Ltd | Manufacturing | 2018 |
| RJ Fahy and SON Ltd | Construction | 2026 |
| RJC Holdings Southern Limited | Information & communication | 2026 |
| Rjyv Limited | Hospitality | 2024 |
| RKD Hospitality Limited | Hospitality | 2020 |
| RKS Unity Team Building (SW) Ltd | Arts & recreation | 2023 |
| RLH Configuration Management Limited | Professional & scientific | 2019 |
| RLJ Solutions Ltd | Professional & scientific | 2020 |
| RMW Laboratories Limited | Manufacturing | 2018 |
| Robert Cockings Motor Repairs Limited | Wholesale & retail | 2008 |
| Robert John Webb Ltd | Construction | 2010 |
| Robert Wilding Building Ltd. | Construction | 2018 |
| Roberts Properties (Somerton) Limited | Real estate | 2013 |
| Robi MH Limited | Transport & logistics | 2024 |
| Robin J Green Limited | Professional & scientific | 2003 |
| Robin James Salons Limited | Administrative & support | 2000 |
| Roics Limited | Administrative & support | 2017 |
| Rommel Guevarra Ltd | Health & social care | 2019 |
| Ronnpatrick Limited | Health & social care | 2015 |
| Roper Excel Consultancy Limited | Professional & scientific | 2018 |
| Rose Data Solutions Limited | Construction | 2008 |
| Rose Hamlet Properties Ltd | Real estate | 2017 |
| Rosebery 1961 Limited | Extraterritorial | 2013 |
| Rosepharm Ltd | Health & social care | 2007 |
| Rosewood Conservation Ltd | Construction | 2017 |
| Rosslink Logistics Limited | Transport & logistics | 2025 |
| Rowlands Cottages Management Company Limited | Households | 2024 |
| Rowsell Holdings Ltd | Financial services | 2019 |
| Rowsell Properties Limited | Real estate | 2017 |
| Rowsell Roofing Limited | Construction | 2000 |
| Rozee Digital Ltd | Professional & scientific | 2019 |
| RPC Grading Ltd | Wholesale & retail | 2023 |
| RPS Asset Management Limited | Real estate | 2013 |
| RS Fitness and PT Limited | Other services | 2018 |
| Ruachdmd Services Ltd | Wholesale & retail | 2026 |
| Ruchi Caters and Event Makers Limited | Hospitality | 2026 |
| Ruhma Care Limited | Transport & logistics | 2014 |
| Rural Business Consultancy Limited | Professional & scientific | 2010 |
| Rust and ROE Limited | Wholesale & retail | 2026 |
| RW Auto Works Ltd | Wholesale & retail | 2025 |
| Ryland Engineering Consultants Ltd | Professional & scientific | 2026 |
| S & K Coombes Contractors Limited | Construction | 1997 |
| S & R Construction (South West) Limited | Construction | 2023 |
| S & S Sheet Metal Limited | Manufacturing | 2003 |
| S B G Creative Ltd | Information & communication | 2022 |
| S C Plumbing (SW) Ltd | Construction | 2024 |
| S C Ratcliffe Ltd | Administrative & support | 2019 |
| S Manley Civil Engineering Limited | Construction | 2005 |
| S P Lenza Ltd | Professional & scientific | 2022 |
| S P Rudkin Ltd | Agriculture & fishing | 2025 |
| S R Vickery Limited | Agriculture & fishing | 2010 |
| S& Associates Ltd | Professional & scientific | 2025 |
| S&J Phillips Properties Ltd | Real estate | 2025 |
| S&J Sanders Electrical Ltd | Construction | 2017 |
| S.W. Brown & Sons (Farming) Limited | Agriculture & fishing | 1979 |
| S3STAYS Ltd | Real estate | 2025 |
| S8VND Ltd | Manufacturing | 2026 |
| SA & LJ Harris Limited | Agriculture & fishing | 2013 |
| Sabelo Mhlungu Ltd | Health & social care | 2014 |
| Safari Enterprise Ltd | Wholesale & retail | 2021 |
| Saffron Associates Ltd | Real estate | 2007 |
| Safia Creative Ltd | Professional & scientific | 2026 |
| Sage Partnering Limited | Administrative & support | 2016 |
| Sage Pro Ltd | Professional & scientific | 2024 |
| Sahara Transport Ltd | Transport & logistics | 2019 |
| SAI Management Services Ltd | Professional & scientific | 2018 |
| Sailaway PA Ltd | Professional & scientific | 2020 |
| Salon 37 Limited | Other services | 2018 |
| Salon Savings Ltd | Wholesale & retail | 2022 |
| Saltaroma Ltd | Transport & logistics | 2020 |
| SAM Contracting Limited | Transport & logistics | 2025 |
| Sandhurst Court Owners Management Company Limited | Real estate | 2018 |
| Sandyhills Property Ltd | Construction | 2026 |
| Sansam Services Limited | Health & social care | 2022 |
| SAO IT Services Limited | Manufacturing | 2008 |
| SAR Management Consultancy Ltd | Professional & scientific | 2017 |
| SAR Property Consultancy Ltd | Construction | 2017 |
| Sarabery Services Limited | Professional & scientific | 2014 |
| Sarah Lyall Interiors Limited | Arts & recreation | 2011 |
| Sardar Scanning Ltd | Health & social care | 2021 |
| Sarga Healthcare Yeovil Limited | Administrative & support | 2026 |
| Sargent & Waight Limited | Agriculture & fishing | 2008 |
| Saron Limited | Real estate | 2017 |
| Satwise TV Limited | Information & communication | 2011 |
| Saunders Simmons Ltd | Information & communication | 2024 |
| Savage Cat Farm Limited | Construction | 1993 |
| Savouri Brands Ltd | Manufacturing | 2022 |
| Saxlingham 2025 Ltd | Manufacturing | 2025 |
| Scales Clothing Limited | Wholesale & retail | 2025 |
| School in a BAG | Other services | 2019 |
| School in a BAG Trading Ltd | Administrative & support | 2020 |
| Scientia Skills Limited | Education | 2009 |
| Scope Architectural Ltd | Professional & scientific | 2026 |
| Scorpio Holdings Ltd | Administrative & support | 2017 |
| Scott Hill Developments (Cheap Street) Limited | Construction | 2022 |
| Scott Hill Holdings Limited | Financial services | 2022 |
| Scottool (UK) Limited | Extraterritorial | 2013 |
| Scottool Limited | Manufacturing | 2008 |
| Screen Bros. Ltd | Professional & scientific | 2021 |