| 1ST4 Limited | Professional & scientific | 2020 |
| Beacon View Pharmacy Limited | Wholesale & retail | 1999 |
| Big River Byker CIC | Construction | 2026 |
| Black Bull Wylam Ltd | Hospitality | 2024 |
| Blue Soul Holistics Ltd | Health & social care | 2005 |
| Boathouse Wylam Ltd | Hospitality | 2019 |
| Bradley Close Farm Ltd | Agriculture & fishing | 2023 |
| Bradley Gardens Limited | Wholesale & retail | 2013 |
| Bridgewater Interiors Limited | Wholesale & retail | 2009 |
| Cairns Chiropractic Limited | Health & social care | 2025 |
| Complete Properties (North East) Limited | Real estate | 2020 |
| Corin Property Ltd | Real estate | 2026 |
| Cornerstone Mews Management Limited | Households | 2006 |
| Craig Little Developments Ltd | Construction | 2022 |
| David Lamb Limited | Financial services | 2009 |
| Dene Building Consultancy Ltd | Other services | 2020 |
| Dunes Management Limited | Professional & scientific | 1988 |
| Earth Doctors Ltd | Manufacturing | 2013 |
| Empire Machinery Services Limited | Manufacturing | 2001 |
| Enlighten Design Limited | Extraterritorial | 2003 |
| Entertainment One (Skelton) Limited | Hospitality | 1987 |
| Explorers NE Holdings Limited | Real estate | 2025 |
| Explorers NE Limited | Health & social care | 2020 |
| Fire in the Hole Catering Limited | Hospitality | 2018 |
| Flying Bird Productions Ltd | Information & communication | 2024 |
| FOX and Hounds Wylam Ltd | Hospitality | 2020 |
| Fricholson Limited | Hospitality | 2022 |
| Graeme Smart Limited | Professional & scientific | 2002 |
| Graham Medical Limited | Professional & scientific | 2012 |
| Greendoc Services Ltd | Health & social care | 2021 |
| GRN Property Management Ltd | Real estate | 2021 |
| GSL Ecology Ltd | Extraterritorial | 2018 |
| Hagg Bank Community Ltd | Administrative & support | 1999 |
| Hilary Florek PR Limited | Professional & scientific | 2004 |
| Howard Muir Associates LLP | | 2006 |
| Inhouse Type Ltd | Information & communication | 2022 |
| Intelligenceya Limited | Information & communication | 2020 |
| Investment Companion Services Ltd | Administrative & support | 2020 |
| J Double L Properties Limited | Real estate | 2024 |
| Jackson Road Residents Association Limited | Households | 1993 |
| James Tetley Consulting Limited | Financial services | 2023 |
| Jasperfish Ltd | Real estate | 2022 |
| Jilldy Property Limited | Households | 2024 |
| John Flynn Consultancy Limited | Other services | 2016 |
| Kablefree-Systems Limited | Manufacturing | 2002 |
| Lish Capital Ltd | Real estate | 2023 |
| Little Adventurers Day Nursery Limited | Health & social care | 2023 |
| Lynch Lettings Ltd | Real estate | 2024 |
| Mabertie Ltd | Information & communication | 2025 |
| Mandaleco Limited | Financial services | 2019 |
| Mansion House (MANAGEMENT)NO2 Limited | Households | 2020 |
| Midori Energy Ltd | Professional & scientific | 2019 |
| Muir Administration Services Ltd | Administrative & support | 2025 |
| Musilience Ltd | Administrative & support | 2026 |
| Next Generation Lettings Ltd | Real estate | 2025 |
| Northern Biogas Solutions Ltd | Professional & scientific | 2013 |
| Opie Associates Ltd | Professional & scientific | 2014 |
| Resource Eleven Limited | Professional & scientific | 2003 |
| Richard Coulson Consultancy Limited | Professional & scientific | 2012 |
| Roseworth (Wylam) Building Estate Limited | Households | 1937 |
| S C Fortune Ltd | Hospitality | 2025 |
| S&R Leisure Ltd | Hospitality | 2023 |
| Shigura Ltd | Information & communication | 2025 |
| Simpson Fine Arts Limited | Wholesale & retail | 2021 |
| Spade and Stone Ltd | Construction | 2025 |
| SPS Consultancy Services Limited | Professional & scientific | 2008 |
| Stuartxwatson Ltd | Health & social care | 2019 |
| Sulky Squirrel Ltd | Manufacturing | 2014 |
| Technical Waste Services Limited | Water & waste | 2017 |
| THE Black Bull (North East) Limited | Hospitality | 2004 |
| THE Tipsy Shed Ltd | Hospitality | 2025 |
| Tyne Valley Wind and Solar Ltd | Construction | 2023 |
| Tyne View Estates Limited | Real estate | 2002 |
| Urban Rent (NE) Limited | Real estate | 2024 |
| Varley Offshore Engineering Limited | Professional & scientific | 2024 |
| VM Secretarial Services Ltd | Administrative & support | 2021 |
| Woodlands Management Company (Ambleside) Limited | Households | 2000 |
| Wylam Pharmacy Limited | Wholesale & retail | 2004 |
| Wylam Ship Inn Ltd | Hospitality | 2025 |
| York Robinson Limited | Real estate | 1946 |
| Zafi Property Limited | Real estate | 2022 |