| UTOPIA68 Limited | Households | 2026 |
| Uwchaled Medical Practice Limited | Health & social care | 2020 |
| V4B Business Finance Limited | Financial services | 2018 |
| V4B Commercial Finance Limited | Professional & scientific | 2019 |
| V4B Paymaster Limited | Professional & scientific | 2018 |
| V4ME Ltd | Financial services | 2020 |
| Valehirst Limited | Agriculture & fishing | 1998 |
| Valhalla Gym Wrexham Ltd | Wholesale & retail | 2025 |
| Validation Consultancy Services Limited | Professional & scientific | 2004 |
| Valley Vapes Ltd | Wholesale & retail | 2018 |
| Valor Drone Services Ltd | Professional & scientific | 2023 |
| Valpharm Consultancy Ltd | Professional & scientific | 2022 |
| Valyandis Real Estate Ltd | Real estate | 2024 |
| Vanessa Nuttall Sound Ltd | Arts & recreation | 2014 |
| Vanguard Technical Services Limited | Manufacturing | 2020 |
| Vanilla Ice Cream Wrexham Ltd | Manufacturing | 2025 |
| Vape Master Chester Limited | Wholesale & retail | 2019 |
| Vasco Consulting Ltd | Mining & quarrying | 2023 |
| Vasuki Investment Ltd | Real estate | 2020 |
| Vault 33 Ltd | Hospitality | 2023 |
| Vauxhall Place Property Ltd | Real estate | 2025 |
| Vectabase Ltd | Information & communication | 2026 |
| Vector GXP Consultancy Ltd | Professional & scientific | 2024 |
| Veged CIC | Education | 2024 |
| Vehicle Cleaning Limited | Administrative & support | 2022 |
| Venns Plastering Limited | Construction | 1995 |
| Ventility Limited | Health & social care | 2018 |
| Vera Private Limited | Wholesale & retail | 2017 |
| Vernons of Wrexham Services Ltd | Transport & logistics | 2019 |
| Vertex Carbon Ltd | Professional & scientific | 2026 |
| Vertuo Limited | Administrative & support | 2010 |
| Vesi Transport Limited | Transport & logistics | 2017 |
| Veterinary Tissue Bank Limited | Manufacturing | 2009 |
| Vexaa Ltd | Wholesale & retail | 2025 |
| Viable Service Solutions Ltd | Administrative & support | 2017 |
| VIC Fit Ltd | Arts & recreation | 2020 |
| Vicroad Limited | Real estate | 2018 |
| Victoria Stores (UK) Limited | Wholesale & retail | 2006 |
| Vieness Limited | Real estate | 2008 |
| Viet Nails and Spa Ltd | Other services | 2025 |
| Vigilant Global Solutions Limited | Administrative & support | 2025 |
| Vigilant SG Limited | Professional & scientific | 2014 |
| Vihana Limited | Real estate | 2024 |
| Viking Big P Ltd | Transport & logistics | 2021 |
| Village Beat Limited | Real estate | 1993 |
| Village Cars Group Ltd | Transport & logistics | 2018 |
| Village Motors Limited | Wholesale & retail | 2006 |
| Village Spice (Wrexham) Ltd | Hospitality | 2019 |
| Vince Rees Roofing Limited | Construction | 2016 |
| Vini CR8IONS Ltd | Other services | 2023 |
| Vintage Mintage Ltd | Information & communication | 2021 |
| Vintage Style Decor Ltd | Professional & scientific | 2020 |
| Vinyl Bear Ltd | Manufacturing | 2012 |
| VIP Wrexham Tours Limited | Administrative & support | 2025 |
| Virgo Beauty Limited | Other services | 2014 |
| Virtual Shopper Ltd | Wholesale & retail | 2023 |
| Visible Construction Partners Ltd. | Construction | 2018 |
| Visible Projects Limited | Professional & scientific | 2016 |
| Vision Competitions Ltd | Other services | 2024 |
| Visionary Roofing and Building Contractors Ltd | Construction | 2025 |
| Visive Group Ltd | Manufacturing | 2000 |
| Viso Property Ltd | Real estate | 2025 |
| Vispa ED Limited | Education | 2024 |
| Vistula Group Limited | Transport & logistics | 2022 |
| Vita Engineering UK Limited | Real estate | 2022 |
| Vita Estates T/A Harding Green Ltd | Real estate | 2024 |
| Vitam Vivere Limited | Households | 2023 |
| Vitaprime Ltd | Wholesale & retail | 2020 |
| Vittoria Property Investments Limited | Real estate | 2011 |
| Viv&Co Ltd | Hospitality | 2016 |
| VJC (UK) Limited | Professional & scientific | 2014 |
| VMS Transport Ltd | Transport & logistics | 2022 |
| Volanto Consulting Ltd | Professional & scientific | 2021 |
| Volanto Group Ltd | Information & communication | 2021 |
| Voltatron Limited | Energy | 2015 |
| Volten Ltd | Manufacturing | 2025 |
| Vorta Network Limited | Information & communication | 2026 |
| Voyager Camper Conversions Ltd | Manufacturing | 2019 |
| Vron Farm Management Company Limited | Households | 2004 |
| Vroom Ltd | Transport & logistics | 2024 |
| VS Beauty Limited | Other services | 2025 |
| VS Surgical Products Ltd | Wholesale & retail | 2024 |
| Vtec CNC Solutions Ltd | Manufacturing | 2010 |
| Vuka Limited | Manufacturing | 2023 |
| Vulcan Asphalt Trading Ltd | Manufacturing | 2026 |
| Vulcan Projects Limited | Professional & scientific | 2020 |
| Vulcana Limited | Education | 2002 |
| VVV Driver Service Ltd | Transport & logistics | 2025 |
| W & S Medical Limited | Health & social care | 2014 |
| W a Brook Plant Hire Limited | Administrative & support | 2004 |
| W Faulkner Agri Ltd | Agriculture & fishing | 2026 |
| W HM & Delivery Ltd | Transport & logistics | 2025 |
| W Squared Media Limited | Professional & scientific | 2020 |
| W.D.M. Qualifications Limited | Education | 2003 |
| W.F.C. (Holywell) Limited | Agriculture & fishing | 1995 |
| W.H. Chaloner & SON Limited | Water & waste | 1951 |
| W.T. Evans Printers Limited | Information & communication | 2002 |
| Wakelegal Ltd | Professional & scientific | 2011 |
| Waking Alan Ltd | Information & communication | 2015 |
| Wales Epilepsy Association CYF. | Health & social care | 1996 |