| I.C.L. Formwork Limited | Construction | 2007 |
| I.Hayward Limited | Wholesale & retail | 1960 |
| I2W Group Limited | Education | 2025 |
| I3 Consultants Ltd | Professional & scientific | 2024 |
| Iain Wylie Consulting Limited | Professional & scientific | 2012 |
| IAN Antony Consulting Limited | Other services | 2008 |
| IAN Ashcroft Electrical Contractors Limited | Construction | 2004 |
| IAN Leech Electrical Contractor Limited | Construction | 2017 |
| IAN Stockdale Limited | Professional & scientific | 2013 |
| IBG International Limited | Administrative & support | 2017 |
| IBG World Limited | Administrative & support | 2013 |
| Iblb Building Services Limited | Construction | 2023 |
| Ice Finance Ltd | Financial services | 2026 |
| ICO Management Services Limited | Information & communication | 2002 |
| Icon Electrical (UK) Ltd | Construction | 2021 |
| Iconiq Aluminium Ltd | Manufacturing | 2025 |
| Iconiq Construction Limited | Construction | 2025 |
| Iconiq Developments Limited | Construction | 2023 |
| Iconiq Renewables Limited | Construction | 2025 |
| Iconiq Studios Ltd | Arts & recreation | 2026 |
| Ideal Comfort Limited | Construction | 1987 |
| Ideal Health Wrexham Ltd | Health & social care | 2026 |
| Idec Construction Limited | Construction | 2019 |
| Identification Solutions Ltd | Other services | 2017 |
| Idris and Bell Ltd | Other services | 2021 |
| IFW - Debt LP | | 2023 |
| Ignite Fabrication Ltd | Manufacturing | 2026 |
| Ijazz Restaurant Ltd | Hospitality | 2025 |
| Ijazz Wrexham Ltd | Hospitality | 2019 |
| Imam Pizza Ltd | Hospitality | 2018 |
| Impact MMA / JSF Ltd | Other services | 2024 |
| Improve Property Ltd | Real estate | 2023 |
| Improved Processes Consulting Ltd | Professional & scientific | 2025 |
| In-Vessel Composting Ltd | Water & waste | 2007 |
| IN2WORK Group Limited | Education | 2026 |
| IN2WORK Limited | Administrative & support | 2024 |
| Ince Contracting Ltd | Construction | 2025 |
| Incidentflow Ltd | Information & communication | 2026 |
| Incredible Edible Wrecsam Limited | Agriculture & fishing | 2024 |
| Independent Twine Manufacturing Company Limited | Manufacturing | 1976 |
| Indessol Limited | Professional & scientific | 2022 |
| Indian Spice Denbigh Limited | Hospitality | 2017 |
| Indiana Sheppard Ltd | Information & communication | 2021 |
| Indpro Limited | Real estate | 2016 |
| Industrial Encoder Distributors Limited | Extraterritorial | 2011 |
| Industrial Encoders Direct Limited | Manufacturing | 1997 |
| Industrial Sensors Direct Limited | Extraterritorial | 2004 |
| Industrial Standard Ltd | Information & communication | 2021 |
| Inet Sales Ltd | Wholesale & retail | 2008 |
| Infinite Possibilities (Global) Limited | Information & communication | 2016 |
| Infinite UK Media Ltd | Professional & scientific | 2025 |
| Inner Calm Collective Limited | Education | 2024 |
| INNOV8 Consultations Limited | Professional & scientific | 2023 |
| INNOV8 Planning Ltd | Professional & scientific | 2023 |
| Innovated by MJ Ltd | Information & communication | 2025 |
| Innovationbk Ltd | Construction | 2025 |
| Innovative Energy Consultancy Ltd | Professional & scientific | 2003 |
| Innovative Energy Ltd | Professional & scientific | 2020 |
| Inpaas UK Ltd | Professional & scientific | 2023 |
| Inspexs Limited | Professional & scientific | 2006 |
| Inspirant Ltd | Information & communication | 2025 |
| Inspire Alpine Ltd | Professional & scientific | 2018 |
| Inspire Hairdressing Limited | Other services | 2013 |
| Inspire WXM Ltd | Health & social care | 2025 |
| INSPIRE1 Retail Limited | Wholesale & retail | 2024 |
| Inspired by Kids Ltd | Wholesale & retail | 2023 |
| Inspirit Bars Limited | Real estate | 2016 |
| Install Depot Ltd | Construction | 2018 |
| Integral Business Support Limited | Other services | 1997 |
| Integrated CAD Services Ltd | Information & communication | 2007 |
| Intelligent Electrical NW Limited | Construction | 2022 |
| Intelligentia LLP | | 2015 |
| Intellisphere AI Ltd | Information & communication | 2025 |
| Intent Inspire Impact Ltd. | Information & communication | 2018 |
| Internal Business Support Ltd | Real estate | 2021 |
| International Association for Educators and Researchers (Iaer) LLP | | 2017 |
| Ioan Said Photography Ltd | Information & communication | 2018 |
| ION Consultants Limited | Professional & scientific | 2019 |
| Ipbg Limited | Real estate | 2021 |
| Ipsen Biopharm Limited | Manufacturing | 1982 |
| Irepair LAB Ltd | Wholesale & retail | 2026 |
| Irwin Family Consultancy Ltd | Professional & scientific | 2026 |
| Isfryn Property Services Limited | Extraterritorial | 2016 |
| Isla Grace Mortgages Ltd | Financial services | 2020 |
| Isma Wrexham Limited | Hospitality | 2016 |
| Isringhausen (G.B) Limited | Manufacturing | 1978 |
| Istabraq Limited | Real estate | 2026 |
| It's a Nerd Thing Ltd | Information & communication | 2025 |
| Itsg World Limited | Administrative & support | 2021 |
| Ivan Transport Ltd | Transport & logistics | 2018 |
| Ivan Warburton Group Ltd | Information & communication | 2025 |
| Ivison Ltd | Professional & scientific | 2025 |
| Ivisonjones Ltd | Transport & logistics | 2011 |
| Ivor Owen & Sons Limited | Transport & logistics | 2006 |
| J & L Elite Travel Ltd | Transport & logistics | 2024 |
| J & P R Limited | Information & communication | 2012 |
| J & S Pipe Services Ltd | Construction | 2020 |
| J D Roofing Ltd | Construction | 2020 |
| J F T Engineering Limited | Manufacturing | 1997 |
| J Fitzpatrick Properties Ltd | Real estate | 2020 |