| Deger Ltd | Hospitality | 2024 |
| Dejager Properties Ltd | Real estate | 2023 |
| Delamere Limited | Professional & scientific | 2020 |
| Delamere Nicolet LLP | | 2023 |
| Delaunay Wealth Management Limited | Financial services | 2012 |
| Delice Peri Peri Ltd | Hospitality | 2019 |
| Delight Indian Cuisine Limited | Hospitality | 2020 |
| Delightful Studios Limited | Information & communication | 2017 |
| Delivery of Thought Ltd | Professional & scientific | 2012 |
| Dellingr Limited | Extraterritorial | 2014 |
| Delta 1 Homes Limited | Real estate | 2024 |
| Delta Circuit Protection and Controls Limited | Professional & scientific | 1946 |
| Delta Engineering Holdings Limited | Professional & scientific | 1963 |
| Delta Holdings Group Ltd | Real estate | 2021 |
| Delta Industries Limited | Professional & scientific | 1971 |
| Delta Limited | Professional & scientific | 1888 |
| Delta Metal Products Limited | Professional & scientific | 1899 |
| Delta Pension Nominees Limited | Professional & scientific | 1968 |
| Delta Projects (Sussex) Ltd | Real estate | 2020 |
| Delta Rods (West Bromwich) Limited | Extraterritorial | 1891 |
| Delta Rods Wolverhampton Limited | Extraterritorial | 1953 |
| Deltaflow Limited | Extraterritorial | 1963 |
| Deluxe Decor & Design Ltd | Construction | 2024 |
| Delville Management UK Limited | Professional & scientific | 2013 |
| Demila Property Staging Ltd | Administrative & support | 2025 |
| Demolition and Dismantling Ltd | Construction | 2020 |
| Demolition Hub Ltd | Information & communication | 2024 |
| Dempsey Hygienist Services Limited | Health & social care | 2016 |
| Dennington Cleaning Services Limited | Administrative & support | 2012 |
| Dental Designs (Sussex) Ltd | Manufacturing | 2022 |
| Dentalbuild Refurbishments Limited | Construction | 2014 |
| Derman OIL UK Limited | Manufacturing | 2025 |
| Design by Monkey Limited | Professional & scientific | 2016 |
| Design Commissioning Ltd | Professional & scientific | 2014 |
| Design Factory (Hove) Ltd | Professional & scientific | 2017 |
| Design JAR Limited | Administrative & support | 2015 |
| Design Magic Limited | Information & communication | 2006 |
| Design Specific Limited | Manufacturing | 2000 |
| Design Studios (South) Limited | Extraterritorial | 2018 |
| Designer Developments Limited | Construction | 1995 |
| Desktop Driving Limited | Wholesale & retail | 1999 |
| Dessaint Holdings Limited | Financial services | 2022 |
| Dessaint Ltd | Wholesale & retail | 2022 |
| Detail Building Contractors Ltd | Construction | 2015 |
| Detail by Brabenger Limited | Transport & logistics | 2023 |
| Detail Design Consultants Ltd | Professional & scientific | 2012 |
| Devan Skuban Ltd | Professional & scientific | 2022 |
| Devian Limited | Health & social care | 2015 |
| Devil Developments Limited | Wholesale & retail | 2008 |
| Devon Digital Imaging Limited | Manufacturing | 2012 |
| Dewulf Film Services Ltd | Administrative & support | 2018 |
| Dexter Developments Ltd | Real estate | 2015 |
| Dexyxxltrade Limited | Wholesale & retail | 2024 |
| DFC Property Management Limited | Real estate | 2015 |
| DG17 Sports Management Ltd | Arts & recreation | 2025 |
| Dharduliya Limited | Hospitality | 2019 |
| DHC Property LLP | | 2021 |
| Dial the Professionals Limited | Extraterritorial | 2000 |
| Diamond Dental Group Ltd. | Health & social care | 2013 |
| Diamond Fitness (Southern) Limited | Arts & recreation | 2018 |
| Diamond Geezer's Worthing Limited | Other services | 2002 |
| Diamond Health & Fitness Ltd | Arts & recreation | 2024 |
| Diamond Recruitment (2018) Ltd | Administrative & support | 2020 |
| Diana Aesthetics Ltd | Education | 2021 |
| Dicentra Developments Ltd | Construction | 2012 |
| Dickies T/A Greys Suit Hire Limited | Other services | 2002 |
| Dickinson Homes Ltd | Real estate | 2024 |
| Diesel Daydreamer 3D Ltd | Wholesale & retail | 2025 |
| Differently Ltd | Other services | 2022 |
| Digby Films Limited | Information & communication | 2011 |
| Digital Commerce Icons Limited | Professional & scientific | 2018 |
| Digital Conversion Limited | Professional & scientific | 2007 |
| Digital Dataflow Limited | Information & communication | 1998 |
| Digital Media Innovations Holdings Limited | Information & communication | 2019 |
| Digital Media Innovations UK Limited | Information & communication | 2019 |
| Digital Word Communications Limited | Professional & scientific | 2017 |
| Dilanti Instruments Limited | Manufacturing | 1990 |
| Dining Enterprises Ltd | Hospitality | 2024 |
| Dinkay Limited | Hospitality | 2020 |
| Dionysus Theatre Ltd | Arts & recreation | 2023 |
| Dirai Spice Ltd | Hospitality | 2019 |
| Direct Technologies Limited | Information & communication | 2018 |
| Directfield Holdings Limited | Real estate | 2021 |
| Directory of Businesses Limited | Information & communication | 2003 |
| Disk Media Limited | Information & communication | 2024 |
| Disquiet Dog Ltd | Professional & scientific | 2014 |
| Dissemble Limited | Arts & recreation | 2025 |
| Distant Peaks Consulting Ltd | Professional & scientific | 2024 |
| Distinction Contracts (International ) Limited | Real estate | 2012 |
| Distinction Contracts Limited | Manufacturing | 2008 |
| Distinction Group International Limited | Financial services | 2015 |
| Distinction Homes Limited | Construction | 2015 |
| Distinction Investments Limited | Financial services | 2015 |
| Distinctive Roofing Ltd | Construction | 2020 |
| District Eleven Holdings Ltd | Financial services | 2021 |
| District Eleven Ltd | Information & communication | 2021 |
| District Eleven Properties Ltd | Real estate | 2023 |
| Ditchling Press Limited | Extraterritorial | 2009 |
| Ditto Fabrics Ltd | Wholesale & retail | 2003 |
| Diversity Motorsport Ltd | Arts & recreation | 2025 |