| Dendro Limited | Households | 2010 |
| Dendrow Homecare Limited | Construction | 2018 |
| Dendrow International Limited | Real estate | 2016 |
| Dendrow Limited | Extraterritorial | 2011 |
| Dennis BOW Limited | Wholesale & retail | 2014 |
| Dentaderm Limited | Health & social care | 2021 |
| Denviktor Ltd | Construction | 2017 |
| DEO Medical Ltd | Health & social care | 2021 |
| Desaga Recruitment Ltd | Other services | 2018 |
| Design Conscious Ltd | Information & communication | 2025 |
| Design Fit Ltd | Manufacturing | 2019 |
| Design Ingenuity Limited | Administrative & support | 2010 |
| Designerfriday Ltd | Wholesale & retail | 2026 |
| Designpower Limited | Administrative & support | 2007 |
| Destined F Greatness D4G Ltd | Wholesale & retail | 2020 |
| Destiny Global Construction and Trading (UK) Ltd | Construction | 2023 |
| Detox Club Ltd | Wholesale & retail | 2026 |
| Detroit Co Ltd | Hospitality | 2026 |
| DEUS56 Ltd | Administrative & support | 2023 |
| DEV Lakshmi Ltd | Real estate | 2023 |
| Devad Ltd | Real estate | 2024 |
| Developments by 6 Limited | Real estate | 2017 |
| Deven Enterprises Ltd | Real estate | 2022 |
| Devexpert Ltd | Information & communication | 2019 |
| DFL Devco Ltd | Construction | 2025 |
| DFL Group Partnership LLP | | 2025 |
| DFL Holdco Ltd | Financial services | 2025 |
| DFL PA Limited | Construction | 2026 |
| DFL PB Limited | Construction | 2026 |
| DFL PD Limited | Construction | 2026 |
| DFL PSC Limited | Construction | 2026 |
| DG & SG Ltd | Hospitality | 2019 |
| DG Roots Company Limited | Wholesale & retail | 2026 |
| DH Properties UK Limited | Real estate | 2017 |
| Dhadda Limited | Wholesale & retail | 2023 |
| Dhaka Drivers Limited | Administrative & support | 2023 |
| Dhanda Developments Ltd | Financial services | 2020 |
| Diamond Beauty Factory Ltd | Health & social care | 2019 |
| Diamond Property Services Ltd | Real estate | 2025 |
| Diamond Services South East Ltd | Administrative & support | 2010 |
| Diana Simion Ltd | Administrative & support | 2025 |
| Diaphragm Pumps & Spares Limited | Manufacturing | 2003 |
| Diaspora Hasjane Ltd | Health & social care | 2025 |
| Different Shapes Ltd | Other services | 2019 |
| Different Things Limited | Wholesale & retail | 2005 |
| Digicolab Consulting Ltd | Information & communication | 2023 |
| Digilogic Solutions Ltd | Information & communication | 2010 |
| Digitaim Limited | Information & communication | 1999 |
| Digital Bridge Partners Ltd | Information & communication | 2023 |
| Digital CRE8 Ltd | Administrative & support | 2024 |
| Digital EYE Candy Ltd | Information & communication | 2019 |
| Digital Movement Limited | Information & communication | 2011 |
| Digital Rabbi Ltd | Professional & scientific | 2021 |
| Dilavena Catering Limited | Hospitality | 2018 |
| Dilbek Limited | Administrative & support | 2014 |
| Dimark Group Limited | Financial services | 2024 |
| Dimk Ltd | Construction | 2024 |
| Dinan Developments Limited | Construction | 2012 |
| Dine in Sauces Limited | Manufacturing | 2014 |
| Ding Studio Ltd | Manufacturing | 2012 |
| Direct Copper Ltd | Construction | 2020 |
| Direct Number LLP | | 2012 |
| Direct Sales Group Limited | Manufacturing | 2021 |
| Direct School Uniform LLP | | 2013 |
| Director Legal Ltd | Professional & scientific | 2023 |
| Directors Group (London) Limited | Real estate | 2014 |
| Directors Group Holding Ltd | Financial services | 2024 |
| Directors Group Investments Ltd | Real estate | 2019 |
| Disco Events Live Ltd | Arts & recreation | 2021 |
| Ditchling Investments Limited | Real estate | 2013 |
| Ditthem Limited | Real estate | 2024 |
| Ditto Cocktail Bar Limited | Hospitality | 2024 |
| Diva Health Limited | Wholesale & retail | 2025 |
| Diyijia Properties Ltd | Real estate | 2025 |
| DJ Master Builders Limited | Construction | 2010 |
| Djans Enterprise Limited | Financial services | 2014 |
| Djme Driver Training Education & Consultancy Limited | Administrative & support | 2020 |
| Djpierce Associates Ltd | Administrative & support | 2016 |
| DJW Coachworks Limited | Professional & scientific | 2008 |
| DK Optometric Services Limited | Health & social care | 2008 |
| DKN Gymnastix Ltd | Education | 2024 |
| DKP London Ltd | Wholesale & retail | 2013 |
| DKS 2020 Ltd | Administrative & support | 2026 |
| DKS Creative Limited | Arts & recreation | 2020 |
| DLK Social Care Limited | Administrative & support | 2006 |
| DLO Investment Properties Ltd | Real estate | 2024 |
| DLP Investments Limited | Financial services | 2025 |
| DLS Consultant Services Ltd | Professional & scientific | 2017 |
| DM & Sons Ltd | Wholesale & retail | 2013 |
| DM Consultancies Limited | Professional & scientific | 2023 |
| DM Fire Limited | Other services | 2016 |
| DM Fire Ventures Ltd | Professional & scientific | 2023 |
| DM Import and Export Ltd | Wholesale & retail | 2025 |
| DMZ Building Services Ltd | Construction | 2025 |
| DNZ World Ltd | Manufacturing | 2015 |
| DO BOP Limited | Real estate | 2024 |
| Dobermann Ltd | Administrative & support | 2024 |
| Dobreh Limited | Real estate | 2012 |
| Doctor Jane Leonard Limited | Health & social care | 2011 |
| Doctor Sneaker Ltd | Wholesale & retail | 2019 |