| Ukgbk Ltd | Construction | 2025 |
| UKH Locum Services Ltd | Health & social care | 2017 |
| Ukinebo Global Group Limited | Hospitality | 2022 |
| Uktrade Express Ltd | Other services | 2024 |
| Ulivetum Limited | Real estate | 2016 |
| Ulticare Limited | Hospitality | 2015 |
| Ultima Safety Ltd | Construction | 2024 |
| Ultimate Bhangra Ltd | Other services | 2022 |
| Ultimate Cleaners (Industrial) Limited | Wholesale & retail | 1986 |
| Ultimate Drainage Ltd | Water & waste | 2021 |
| Ultimate Electrical Solutions Ltd | Construction | 2018 |
| Ultimate Penn Healthcare Limited | Administrative & support | 2023 |
| Ultimate Plumbing Services Limited | Construction | 2000 |
| Ultimate Warriors CIC | Arts & recreation | 2022 |
| Ultra Global Limited | Transport & logistics | 2011 |
| Ultra Metal UK Ltd | Manufacturing | 2020 |
| Ultracare Waste Solutions Limited | Administrative & support | 2008 |
| Ultralace Ltd | Manufacturing | 2023 |
| Ultravend Hygiene Services Limited | Administrative & support | 2003 |
| Umar Getaways Ltd | Real estate | 2025 |
| Umbral Software Limited | Information & communication | 2020 |
| Umei Services Ltd | Construction | 2025 |
| Unassume Ltd | Information & communication | 2026 |
| Unchained Tours Limited | Administrative & support | 2015 |
| Uncle & Nephew Tyres Ltd | Wholesale & retail | 2025 |
| Underhill Langley and Wright Ltd | Professional & scientific | 2014 |
| Undone Hair Ltd | Other services | 2019 |
| Uneostious Ltd | Health & social care | 2021 |
| Unger U.K. Limited | Wholesale & retail | 1997 |
| Unidraught Limited | Professional & scientific | 2007 |
| Unified World Ltd | Administrative & support | 2019 |
| Uniglobe Trading Ltd | Other services | 2009 |
| Unii Shop Ltd | Hospitality | 2026 |
| Uniland Ltd | Wholesale & retail | 2021 |
| Unimetal Ltd | Professional & scientific | 2013 |
| Union Build Limited | Construction | 2019 |
| Union Steel Tubes Limited | Wholesale & retail | 2004 |
| Unionshopx Ltd | Wholesale & retail | 2026 |
| Unique and Geek Ltd | Manufacturing | 2017 |
| Unique Concepts Consultancy Limited | Construction | 2012 |
| Unique Courier Ltd | Transport & logistics | 2018 |
| Unique Drywall Finishers Ltd | Construction | 2018 |
| Unique Facility Management Limited | Information & communication | 2016 |
| Unique Finish Walls Ltd | Manufacturing | 2023 |
| Unique GB Driver Training Ltd | Education | 2024 |
| Unique Ideas (UK) Limited | Other services | 1992 |
| Unique Mobiles Tech Ltd | Manufacturing | 2019 |
| Unique Mobiles Tech Services Ltd | Wholesale & retail | 2021 |
| Unique Movez Dance Collective CIC | Education | 2023 |
| Unique Presents Limited | Wholesale & retail | 2020 |
| Unique Soundz Roadshow Limited | Arts & recreation | 2012 |
| Unique Style Limited | Wholesale & retail | 2009 |
| Unisex Tanning and Beauty Limited | Other services | 2016 |
| Unisi Ltd | Professional & scientific | 2023 |
| Unit 16 Grill Ltd | Hospitality | 2026 |
| Unit Garage Limited | Wholesale & retail | 2011 |
| United Auto Brokerage Ltd | Wholesale & retail | 2014 |
| United Bright Bar Co. Limited | Manufacturing | 1978 |
| United Driveways Limited | Construction | 2021 |
| United Electrical Products Limited | Manufacturing | 2004 |
| United Global Dezign’S Ltd | Manufacturing | 2025 |
| United Handicrafts PVT Ltd | Manufacturing | 2026 |
| United Maintenance Ltd | Administrative & support | 2021 |
| United Motors 4U Limited | Wholesale & retail | 2025 |
| United Paints & Chemicals Ltd | Wholesale & retail | 2023 |
| United Plant Training Ltd | Other services | 2021 |
| United Social Work Limited | Professional & scientific | 2013 |
| United Supermarket (Wolves) Limited | Wholesale & retail | 2021 |
| UNITED4CARE Limited | Health & social care | 2025 |
| Unitline Ltd | Construction | 2026 |
| Unitty Specialist Cleaning Limited | Administrative & support | 2011 |
| Unity Barbers Ltd | Other services | 2024 |
| Unity Crescent Ltd | Wholesale & retail | 2026 |
| Unity House International Ltd | Other services | 2024 |
| Unity Housing Group Ltd | Real estate | 2022 |
| Unity in Action CIC | Arts & recreation | 2024 |
| Unity Primary Care Ltd | Health & social care | 2018 |
| Unity Properties Group Limited | Construction | 2026 |
| Unity Supported Accommodation CIC | Hospitality | 2020 |
| Universal Branding Ltd | Manufacturing | 2023 |
| Universal Building Plastics Limited | Wholesale & retail | 2019 |
| Universal Cloud Ltd | Information & communication | 2018 |
| Universal Courier Logistical Services Ltd | Administrative & support | 2017 |
| Universal Ecig Limited | Construction | 2011 |
| Universal Merchandise Ltd | Wholesale & retail | 2021 |
| Universal Production Rentals Ltd | Administrative & support | 2025 |
| Universal Property Lettings Ltd | Real estate | 2024 |
| Universal Trade Windows Limited | Construction | 2016 |
| University of Wolverhampton Students' Union | Education | 2010 |
| Unix Group Ltd | Construction | 2025 |
| Unlimited TCG Ltd | Wholesale & retail | 2026 |
| Unova Operations U.K. Limited | Professional & scientific | 1996 |
| UO Tanner Ltd | Transport & logistics | 2022 |
| UOW Employment Services Limited | Administrative & support | 2023 |
| UP Ultra Pure Ltd. | Wholesale & retail | 2020 |
| Upar Simran Transport Ltd | Transport & logistics | 2021 |
| Upfront Legal Limited | Administrative & support | 2026 |
| Upgrace Beauty Ltd | Other services | 2024 |
| UPH Properties Ltd | Real estate | 2023 |
| Upmarket Property Solutions Limited | Real estate | 2025 |