| Surinder Trading Ltd | Wholesale & retail | 2024 |
| Surma 26 Ltd | Hospitality | 2026 |
| Surveywolf Consultants Ltd | Professional & scientific | 2019 |
| Susan Vickers C.I.C. | Public administration | 2024 |
| Susch Legacy Holdings Limited | Financial services | 2025 |
| Sustain Ethics Limited | Wholesale & retail | 2022 |
| Sustain Grow International C.I.C. | Other services | 2024 |
| Sustainable Energy Design House Ltd | Administrative & support | 2024 |
| Sustainable Freight Solutions Ltd | Professional & scientific | 2012 |
| Sustained Trades Ltd | Information & communication | 2021 |
| Sutherland Grove Management Company Limited | Real estate | 2003 |
| Sutton Traders Limited | Wholesale & retail | 2022 |
| Suttons Medics 101 Limited | Health & social care | 2024 |
| Suzi Perry Limited | Information & communication | 2003 |
| SV Consultancy Ltd | Information & communication | 2014 |
| SV International Property Limited | Real estate | 2024 |
| SV Property Management Ltd | Real estate | 2025 |
| SV Transportation Ltd | Transport & logistics | 2025 |
| SV88 Ltd | Administrative & support | 2023 |
| Svdns Ltd | Wholesale & retail | 2024 |
| SVL Management Systems Limited | Professional & scientific | 2012 |
| SVR Developments Ltd | Real estate | 2021 |
| SVS Hair & Beauty Limited | Administrative & support | 2004 |
| SW Cladding Ltd | Construction | 2017 |
| SW GAS and Heating Ltd | Construction | 2015 |
| SW Plumbing & Drainage Ltd | Construction | 2018 |
| Swagemaster Engineering Services Limited | Manufacturing | 2000 |
| Swagemaster Engineering Support Ltd | Manufacturing | 2020 |
| Swagemaster Holdings Limited | Financial services | 2014 |
| Swain & Company Limited | Professional & scientific | 2002 |
| Swain Fire & Security Ltd | Manufacturing | 2023 |
| Swan Armitage Ltd | Hospitality | 2019 |
| Swan Care Solutions Ltd | Health & social care | 2018 |
| Swan Haulage Limited | Extraterritorial | 2022 |
| Swancote Energy Holdings Limited | Financial services | 2018 |
| Swancote Energy Limited | Water & waste | 2010 |
| Swancote Property Holdings Limited | Financial services | 2022 |
| Swancote Property Limited | Financial services | 2018 |
| Swandream Limited | Other services | 2025 |
| SWANIKA16 Ltd | Real estate | 2025 |
| Swans Hand Car Wash Ltd | Administrative & support | 2025 |
| Swanston Holdings Public Limited Company | Real estate | 2001 |
| Swao Ltd | Health & social care | 2020 |
| Swap & Go Network Ltd | Construction | 2020 |
| Swapline Holdings Limited | Real estate | 2020 |
| Swarbourn Landscapes Ltd | Administrative & support | 2023 |
| Sweeney Fire and Training Ltd | Financial services | 2022 |
| Sweet 16 Ltd | Manufacturing | 2026 |
| Sweet Day by Tatiana Ltd | Hospitality | 2024 |
| Sweet Elohim Afro Market Ltd | Wholesale & retail | 2022 |
| Sweet Elohim Afro Resto Ltd | Hospitality | 2022 |
| Sweet Home Fitted Wardrobes Ltd | Other services | 2020 |
| Sweet Home Holdings Ltd | Real estate | 2025 |
| Sweet Mother Community Services CIC | Administrative & support | 2026 |
| Sweet Spring Developments Limited | Construction | 2007 |
| Sweetheart Tattoo Parlour Ltd | Other services | 2023 |
| Sweetphoria Ltd | Wholesale & retail | 2026 |
| SWH Haulage Ltd | Transport & logistics | 2024 |
| Swift Appliance Repair Ltd | Extraterritorial | 2025 |
| Swift Onboard Ltd | Professional & scientific | 2023 |
| Swift Resolve Investments Limited | Real estate | 2025 |
| Swift Source Nexus Ltd | Wholesale & retail | 2026 |
| Swift Wear Ltd | Wholesale & retail | 2017 |
| Swift Wholesale Ltd | Wholesale & retail | 2021 |
| Swiftcart Britian Trendora UK Ltd | Wholesale & retail | 2026 |
| Swiftform Limited | Wholesale & retail | 2011 |
| Swiftsave UK Ltd | Wholesale & retail | 2001 |
| Swiftscript Ltd | Health & social care | 2023 |
| Swiftwire Ltd | Financial services | 2025 |
| Swinford UK Limited | Wholesale & retail | 2009 |
| Switch on Security Limited | Administrative & support | 2009 |
| Switch UP Care Ltd | Health & social care | 2024 |
| Sword Land Systems Ltd | Financial services | 2025 |
| SWR Building Solutions LDT Ltd | Construction | 2025 |
| SWR Heating, Plumbing & GAS Limited | Construction | 2023 |
| Swsol Ltd | Administrative & support | 2024 |
| Swynwood Property Ltd | Administrative & support | 2017 |
| Syberaxe Limited | Information & communication | 2015 |
| Syed A&H Online Ltd | Wholesale & retail | 2024 |
| Syed Moiz Trading Ltd | Wholesale & retail | 2026 |
| Syed Taxi Services Ltd | Transport & logistics | 2026 |
| Sylia Properties Limited | Real estate | 2024 |
| Sylvercrown Solutions Ltd | Administrative & support | 2025 |
| Synagenia Ltd | Wholesale & retail | 2019 |
| Synapse Social Care Limited | Transport & logistics | 2025 |
| Synaxis Design Consultancy Limited | Professional & scientific | 2013 |
| Sync Chem Ltd | Wholesale & retail | 2008 |
| Synergy Design Consultancy Ltd | Administrative & support | 2014 |
| Synergy Estates Group Limited | Real estate | 2021 |
| Synergy IT Solutions and Management Ltd | Information & communication | 2017 |
| Synergy Learning Hub Ltd | Wholesale & retail | 2026 |
| Synergy Lettings Plus Limited | Real estate | 2023 |
| Synergy Pictures UK Ltd | Information & communication | 2026 |
| Synergy Resourcing Limited | Construction | 2020 |
| Synox Ltd | Wholesale & retail | 2024 |
| SYO Properties Limited | Real estate | 2025 |
| Syona Ltd | Health & social care | 2026 |
| Syscus Limited | Professional & scientific | 2023 |
| Sysdata Cloud Group Ltd | Information & communication | 2026 |
| System 21 Limited | Professional & scientific | 1983 |