| Safe Move Solutions Ltd | Transport & logistics | 2025 |
| Safe Offshore Services Ltd | Real estate | 2012 |
| Safe School Ride Ltd | Transport & logistics | 2025 |
| Safe-Matter Ltd | Professional & scientific | 2025 |
| Safecore Security Limited | Administrative & support | 2024 |
| Safenighthostel Ltd | Professional & scientific | 2025 |
| Safety Cctv Ltd | Construction | 2022 |
| Safety Critical Staff Limited | Construction | 2013 |
| Safeway Contracting UK Limited | Construction | 2019 |
| Safewise Health, Safety and HR Advisors Ltd | Professional & scientific | 2012 |
| Safewise Talent Ltd | Administrative & support | 2025 |
| Saffron 1972 Limited | Extraterritorial | 2014 |
| Saffron Care Group Limited | Administrative & support | 2017 |
| Saffy Shipping Services Ltd | Wholesale & retail | 2025 |
| Safri Brothers Ltd | Real estate | 2024 |
| Sagar Sweet Centre & Take Away Ltd | Hospitality | 2013 |
| Sagarmatha Private Limited | Hospitality | 2022 |
| Saggal Property Ltd | Real estate | 2026 |
| Saggu Consultancy Services Limited | Wholesale & retail | 2018 |
| Sagnadions Ltd | Administrative & support | 2019 |
| SAH 77 Ltd | Other services | 2019 |
| Sahana Locums Ltd | Health & social care | 2019 |
| Sahara Cleaning Services (Midlands) Ltd | Administrative & support | 2011 |
| Sahavedana Ltd | Health & social care | 2022 |
| Saheser Ltd | Administrative & support | 2021 |
| Sahi Construction Ltd | Construction | 2025 |
| Sahi Transport Ltd | Transport & logistics | 2017 |
| Sahib Construction Limited | Construction | 2016 |
| Sahib Shopfront and Shutters Ltd | Manufacturing | 2024 |
| Sahib Transport Ltd | Transport & logistics | 2017 |
| Sahils Kwik Stop Ltd | Wholesale & retail | 2025 |
| Sahni Medical Services Limited | Health & social care | 2024 |
| Sahota Associates Limited | Real estate | 2022 |
| Sahota Commercial Holdings Ltd | Real estate | 2024 |
| Sahota Construction Midland Ltd | Construction | 2022 |
| Sahota Healthcare Limited | Public administration | 2022 |
| Sahota Holdings Ltd | Real estate | 2018 |
| Sahota JS Transport Ltd | Transport & logistics | 2021 |
| Sahz Consulting Ltd | Information & communication | 2023 |
| Sahz Homes Ltd | Real estate | 2024 |
| SAI Development Ltd | Real estate | 2020 |
| SAI Kitchen & Bedroom Limited | Construction | 2022 |
| Saigates Limited | Wholesale & retail | 2014 |
| Sails Link Ltd | Wholesale & retail | 2025 |
| Saini Digging & Construction Services Ltd | Construction | 2016 |
| Saini Property Rentals Ltd | Real estate | 2022 |
| Saini Real Estates Ltd | Construction | 2024 |
| Saint Berlyn London Ltd | Wholesale & retail | 2025 |
| Saint Concepts Limited | Information & communication | 2025 |
| Saint Donciere Ltd | Manufacturing | 2024 |
| Saint ONO Tattoo Ltd | Arts & recreation | 2025 |
| Saints Training Ltd | Administrative & support | 2014 |
| Saites Transport Ltd | Transport & logistics | 2022 |
| Saith Estore Ltd | Wholesale & retail | 2026 |
| Sajad Mart Ltd | Wholesale & retail | 2025 |
| Sajb Group Ltd | Real estate | 2019 |
| Saju Ltd | Construction | 2026 |
| SAK Property Ltd | Real estate | 2022 |
| SAL Singh Ltd | Construction | 2024 |
| Salad Master Outlet Ltd | Wholesale & retail | 2025 |
| Salamanda Swimming Academy Ltd | Arts & recreation | 2010 |
| Salamanderwindows.Co.Uk Ltd. | Real estate | 1998 |
| Salar's Fresh Fruit & VEG Ltd | Wholesale & retail | 2026 |
| Sale Seekerz Ltd | Information & communication | 2023 |
| Salesco Ltd | Manufacturing | 2026 |
| Salespulse Ltd | Information & communication | 2025 |
| Salient Global Ltd | Wholesale & retail | 2023 |
| Salifat Ltd | Administrative & support | 2024 |
| Salis&Alhassan Ltd | Health & social care | 2021 |
| Sally Lawson Limited | Real estate | 1998 |
| Salman AA Ltd | Wholesale & retail | 2025 |
| Salman.Ecom Ltd | Wholesale & retail | 2026 |
| Salon 1 (Wolverhampton) Limited | Other services | 2019 |
| Salon 612 Ltd | Other services | 2023 |
| Salon Style Collections Limited | Wholesale & retail | 2023 |
| Salon Supply Group Ltd | Wholesale & retail | 2019 |
| Salsa Grill Ltd | Hospitality | 2021 |
| Salters Developments Limited | Real estate | 2006 |
| Salti Limited | Wholesale & retail | 2026 |
| Salvage Auto Direct Ltd | Wholesale & retail | 2025 |
| Salwa Khalil Services Limited | Health & social care | 2016 |
| Salwas Limited | Wholesale & retail | 2014 |
| Salyrex Ltd | Wholesale & retail | 2026 |
| SAM & Jess Transport Ltd | Transport & logistics | 2022 |
| SAM Burke Holdings Limited | Professional & scientific | 2017 |
| SAM Construction Birmingham Ltd | Construction | 2022 |
| SAM Construction West Midlands Ltd | Construction | 2023 |
| SAM Investments Private Limited | Health & social care | 2017 |
| SAM Midlands Limited | Hospitality | 2025 |
| SAM Moore Writer Limited | Information & communication | 2024 |
| SAM Sensory and Consumer Research UK Limited | Professional & scientific | 2002 |
| SAM Vegetables Limited | Wholesale & retail | 2019 |
| SAM Wolves Limited | Hospitality | 2026 |
| SAM ZSU Ltd | Transport & logistics | 2026 |
| Sam's Barbers (Wolverhampton) Limited | Other services | 2022 |
| Sam's Electrical Services Wolverhampton Ltd | Construction | 2020 |
| Samama Qamar Limited | Wholesale & retail | 2025 |
| Samb Sadashiv Ltd | Real estate | 2026 |
| Samband Developments Ltd | Real estate | 2025 |
| Sambani Construction Ltd | Construction | 2021 |