| SPG Controls Ltd | Information & communication | 2022 |
| Spherical Consulting Ltd | Professional & scientific | 2021 |
| Sphinx Fine Art Limited | Wholesale & retail | 2007 |
| Spiderfish Limited | Information & communication | 2008 |
| Spin Data Ltd | Information & communication | 2025 |
| Spink Holdings Limited | Financial services | 2018 |
| SPM Consultancy Ltd | Information & communication | 2016 |
| Spoonful Limited | Manufacturing | 2014 |
| Spoorty Solutions Ltd | Information & communication | 2018 |
| Sport Rules Ltd | Education | 2018 |
| Sportainment Global Ltd | Information & communication | 2024 |
| Sportz Action Productions Limited | Information & communication | 2007 |
| SPP Property Ltd | Real estate | 2015 |
| Spray Yard Ltd | Construction | 2022 |
| Spraychoice (Woking) Limited | Construction | 1999 |
| Spring Scientific Limited | Professional & scientific | 1995 |
| Springtide Bathrooms Limited | Construction | 2006 |
| Springvale Medical Services Ltd | Health & social care | 2015 |
| Springwell (Havant) Management Company Limited | Real estate | 2006 |
| SPS Property Limited | Real estate | 2018 |
| Squalo Limited | Manufacturing | 2022 |
| Squandle Ltd | Wholesale & retail | 2021 |
| Square 21 Accounting & Tax Solutions Ltd | Professional & scientific | 2020 |
| Square Claims and Works Management Ltd | Financial services | 2014 |
| Squared Earth Limited | Administrative & support | 2012 |
| Squirt Electrical Services Ltd | Construction | 2021 |
| SR Invest Limited | Real estate | 2025 |
| SR Smith Consultancy Ltd | Information & communication | 2011 |
| SR Tech Consultancy Ltd | Information & communication | 2026 |
| Sr.S.S FM Ltd | Hospitality | 2022 |
| Sreenesh Limited | Health & social care | 2014 |
| Sreeyam Homes Ltd | Hospitality | 2021 |
| SRI SK IT Consulting Ltd | Information & communication | 2014 |
| Sriya Care Ltd | Real estate | 2024 |
| Srpp Holdings (UK) Limited | Wholesale & retail | 2020 |
| SRS Berkshire Limited | Health & social care | 2024 |
| SRS Works Limited | Information & communication | 2015 |
| SRW Design Services Ltd | Professional & scientific | 2020 |
| SS Driving School Ltd | Education | 2022 |
| SSC Maidenhead Ltd | Arts & recreation | 2026 |
| SSC Westealing Ltd | Arts & recreation | 2025 |
| SSJ Projects Ltd | Information & communication | 2014 |
| SSL Business Solutions Ltd | Other services | 2013 |
| SSM Tech Ltd | Information & communication | 2021 |
| Ssmarttec Ltd | Information & communication | 2025 |
| SSR Advisory Ltd | Manufacturing | 2026 |
| SSS IT Consultants Ltd | Information & communication | 2022 |
| ST Denis Productions Limited | Information & communication | 2024 |
| ST Ives Watersports Limited | Transport & logistics | 2020 |
| Stablecroft Limited | Other services | 2020 |
| Stabllux Ltd | Arts & recreation | 2023 |
| Stacey Stockwell Training Ltd | Administrative & support | 2018 |
| Stackgenic Ltd | Information & communication | 2019 |
| Stafford Bridge Doors Limited | Manufacturing | 1999 |
| Stage Fifty UK Ltd | Administrative & support | 2020 |
| Stainsby Contracts Ltd | Construction | 2015 |
| Stanbury Gate Management Company Limited | Households | 1987 |
| Standbrook Consultants Limited | Professional & scientific | 1999 |
| Stanley Chiropractic Ltd | Health & social care | 2024 |
| Stanmarle Developments(Wokingham)Limited | Real estate | 1966 |
| Stanza Design Limited | Professional & scientific | 1999 |
| Star Cars Reading Limited | Transport & logistics | 2017 |
| Stars in the Cloud Ltd | Information & communication | 2016 |
| Starsigns Consultancy Ltd | Professional & scientific | 2025 |
| Startup Stage Limited | Financial services | 2022 |
| Starwiz Limited | Information & communication | 2020 |
| Station Barbers Wokingham Ltd | Other services | 2025 |
| Station Court Management Company (Thatcham) Limited | Households | 1988 |
| Stats Matters Ltd | Professional & scientific | 2024 |
| Staysure Limited | Wholesale & retail | 1986 |
| Staysure Tyres Limited | Extraterritorial | 2001 |
| Steam Cream Limited | Wholesale & retail | 2008 |
| Stean 360 Ltd | Construction | 2021 |
| Steel & Linen Family Partnership LLP | | 2020 |
| Steel & Linen Properties Ltd | Construction | 2020 |
| Steer Property Group Limited | Real estate | 2024 |
| Stega Transport Limited | Transport & logistics | 2018 |
| Steiner Consultancy Ltd | Information & communication | 2020 |
| Stela Marine Limited | Professional & scientific | 2015 |
| Stellacare Ltd | Health & social care | 2025 |
| Stellar Consult Ltd | Information & communication | 2025 |
| Stellar Engines Ltd | Professional & scientific | 2012 |
| Stephens Leisure Limited | Real estate | 1989 |
| Sterling Pixels Ltd. | Information & communication | 2012 |
| Sterling Square (Bracknell) Management Company Limited | Real estate | 2018 |
| Steuer Consulting Limited | Financial services | 2011 |
| Steve Carr Aviation Ltd | Transport & logistics | 2021 |
| Steven Behan Window Cleaning Ltd | Administrative & support | 2014 |
| Sticks & Stones Productions Limited | Arts & recreation | 2003 |
| Stlb Construction Services Ltd | Construction | 2025 |
| STN Star Limited | Administrative & support | 2025 |
| Stokes Housing Limited | Real estate | 2022 |
| Stone Hair Design Limited | Extraterritorial | 2013 |
| Stone Place (Gosbrook Road) Management Company Limited | Households | 2013 |
| Stovi Group Limited | Real estate | 2025 |
| Strada Real Estate Partners Limited | Real estate | 2025 |
| Straight Line Retail Recruitment Limited | Administrative & support | 2009 |
| Strange the Jewellers Limited | Wholesale & retail | 1987 |
| Strata Apex Ltd | Wholesale & retail | 2026 |
| Strategic Advisory & Security Limited | Information & communication | 2026 |