| EP UK Newco Limited | Financial services | 2022 |
| Ephratah Services Ltd | Public administration | 2018 |
| Epiderm Solutions Ltd | Professional & scientific | 2025 |
| Episteme Computer Systems Limited | Information & communication | 1995 |
| Equilibrium Recruitment Ltd | Administrative & support | 2006 |
| Equilux Solutions Ltd | Agriculture & fishing | 2025 |
| Equinox People Partners Limited | Professional & scientific | 2020 |
| Equinox Property Management and Solutions Ltd | Households | 2024 |
| Equitrade Services Ltd | Households | 2025 |
| Equiventum Ltd. | Wholesale & retail | 2020 |
| Eric Hunter Limited | Wholesale & retail | 2001 |
| Ericon Investments | Administrative & support | 2022 |
| Eriden Ltd | Wholesale & retail | 2019 |
| Eriksen Consulting Ltd | Professional & scientific | 2014 |
| ERP Tech Solutions Limited | Information & communication | 2012 |
| ES Building Solution Ltd | Construction | 2016 |
| Escarate LLP | | 2016 |
| Esensi Ltd | Public administration | 2014 |
| Esharp Financial Services Limited | Professional & scientific | 2009 |
| ESP Accountancy Limited | Professional & scientific | 2005 |
| Esperenza LLP | | 2025 |
| Espiner Consulting Ltd | Professional & scientific | 2014 |
| Esprit Kids Ltd | Arts & recreation | 2022 |
| Essay Plug Ltd | Education | 2025 |
| Essential PV Consulting Ltd | Professional & scientific | 2023 |
| Eternal Freedom Consulting LLP | | 2023 |
| Eternella LLP | | 2025 |
| Eton (Slough) Management Company Limited | Households | 1984 |
| EU Plants Limited | Agriculture & fishing | 2004 |
| Eurasia Policy Forum Limited | Professional & scientific | 2026 |
| Eurasian Linguistic Services Limited | Professional & scientific | 2011 |
| Eurep UK Ltd | Wholesale & retail | 2022 |
| Europium Legal Limited | Professional & scientific | 2022 |
| Eurritmia Magazine Limited | Manufacturing | 2022 |
| Euzen Ltd | Information & communication | 2019 |
| Evelina Healthcare Ltd | Health & social care | 2024 |
| Evendons Residents Management Company Limited | Real estate | 2015 |
| Eventsnation Ltd | Administrative & support | 2022 |
| Ever Forwards Partnership LLP | | 2023 |
| Evergreen Strategy Partners Limited | Professional & scientific | 2007 |
| Everhaul Limited | Real estate | 2016 |
| Everscope Limited | Construction | 2014 |
| Everstead Care Limited | Health & social care | 2025 |
| Evertz UK Limited | Manufacturing | 1997 |
| Everwood Wills Ltd | Administrative & support | 2025 |
| Everyday Athlete Wellness Ltd | Information & communication | 2026 |
| Everystate Ltd. | Wholesale & retail | 2023 |
| Everything Dogs Ltd | Other services | 2011 |
| Evesham Mews Management Company Limited | Households | 2013 |
| Evgeniya Thornhill Marketing Consulting Limited | Professional & scientific | 2014 |
| Evidence IT Limited | Information & communication | 2009 |
| Evmotive Ltd | Professional & scientific | 2022 |
| Evobridge Limited | Professional & scientific | 2013 |
| Evolution House Ltd | Real estate | 2019 |
| Evolution Services Limited | Arts & recreation | 2013 |
| Evolve CM Ltd | Public administration | 2019 |
| Evolve UK Property Ltd | Construction | 2019 |
| Ex-Tiquette Holdings Ltd | Real estate | 2021 |
| Exact Kitchens Limited | Construction | 2003 |
| Exalted Property Limited | Real estate | 2013 |
| Exam Analysis Ltd | Information & communication | 2021 |
| Exam Study Expert Ltd | Education | 2022 |
| Excelat Limited | Professional & scientific | 2009 |
| Exclusive Construction Ltd | Construction | 2013 |
| Execdash Ltd | Information & communication | 2025 |
| Executive Coaching Psychology Company Limited | Professional & scientific | 2024 |
| Exhilarate Ltd | Arts & recreation | 2023 |
| Exlin Ltd | Wholesale & retail | 2019 |
| Exlin Pro Ltd | Wholesale & retail | 2026 |
| Exo-Cubic Engineering Ltd. | Professional & scientific | 2018 |
| Exodus Rooms Limited | Administrative & support | 2016 |
| Expand Design Ltd | Professional & scientific | 2009 |
| Expandbio Limited | Professional & scientific | 2023 |
| Experimentus Ltd. | Information & communication | 2004 |
| Expert Consulting Solutions Limited | Administrative & support | 2015 |
| Expert Velocity Ltd | Professional & scientific | 2020 |
| Exploit Edge Ltd | Administrative & support | 2024 |
| Explore Inventories Limited | Real estate | 2016 |
| Exsite Consultants Limited | Information & communication | 2002 |
| External Grounds Maintenance Ltd | Construction | 2021 |
| Extra Crew Ltd | Professional & scientific | 2002 |
| Extraordinary Life C.I.C. | Other services | 2022 |
| Extreme Lifting Holdings Limited | Financial services | 2026 |
| Extreme Lifting Limited | Manufacturing | 2007 |
| EYE2EYE Contact Ltd | Wholesale & retail | 2013 |
| Ezbz Properties Ltd | Real estate | 2022 |
| Ezbz Solutions Ltd | Information & communication | 2013 |
| Ezbz Trading Limited | Financial services | 2021 |
| F & R Builders Limited | Construction | 2018 |
| F P R Associates Limited | Professional & scientific | 2006 |
| F R Transport Limited | Transport & logistics | 2014 |
| F&P Agency Ltd | Real estate | 2022 |
| F&R Assets Limited | Construction | 2022 |
| F1 Consultancy Limited | Information & communication | 1995 |
| Fab-It Consulting Ltd | Information & communication | 2012 |
| Face to Face Training Ltd | Education | 2024 |
| Factoryfirst.Com Hold Co Ltd | Financial services | 2026 |
| Fairfield House (Sunningdale) Residents Management Company Limited | Households | 2011 |
| Fairlawns (Tadley) Management Company Limited | Households | 1985 |
| Fairview Conservatories Limited | Construction | 1981 |