| Starwood Solutions Ltd | Administrative & support | 2012 |
| Station House Midhurst Limited | Households | 2018 |
| Stay Aura Ltd | Real estate | 2024 |
| Steadfast Infrastructural Limited | Financial services | 2025 |
| Steadicamsa Films Ltd | Information & communication | 2021 |
| Stecanella Business Solutions Ltd | Information & communication | 2023 |
| Steel Bars Limited | Administrative & support | 2010 |
| Steel Bars Search Limited | Administrative & support | 2011 |
| Stego Limited | Arts & recreation | 2012 |
| Stella Interior Contracts Ltd | Construction | 2009 |
| Step Inn Direct Ltd | Hospitality | 2017 |
| Step One Finance Limited | Financial services | 2010 |
| Step One Money UK Limited | Financial services | 2024 |
| Stephanie Richardson Consulting Ltd | Other services | 2018 |
| Stephen Child Consultancy Limited | Construction | 2010 |
| Stephen Kavanagh Architects Ltd | Professional & scientific | 2015 |
| Stephen Lord Limited | Information & communication | 2021 |
| Stepping Stones to Development Ltd | Professional & scientific | 2011 |
| Sterling Estimating Services Limited | Construction | 2003 |
| Sterling Habitat Limited | Real estate | 2020 |
| Sterling II Limited | Administrative & support | 2018 |
| Sterling Meridian Limited | Health & social care | 2012 |
| Sterling Office Services Limited | Other services | 2009 |
| Sterling PMD Ltd | Construction | 2023 |
| Sterling Pubs and Bars Ltd. | Hospitality | 2019 |
| Sterling Retail Services Ltd | Information & communication | 2018 |
| Sterlingdale Properties Limited | Construction | 2024 |
| Steve Keywood Ltd | Education | 2019 |
| Steve Mitchell Consulting Limited | Professional & scientific | 2024 |
| Steve Pratt Coaching Limited | Professional & scientific | 2017 |
| Steve Tait Music Limited | Arts & recreation | 2014 |
| Steven Johnson Productions Limited | Information & communication | 2017 |
| Steven Pell Properties Ltd | Real estate | 2021 |
| Stevenage Developments Ltd | Construction | 2016 |
| Stevenage Refurbishments Ltd | Construction | 2009 |
| STG Fabrications Services LLP | | 2010 |
| Stichting Chemical Distribution Institute | | 1994 |
| STIRB73 Ltd | Manufacturing | 2021 |
| STL Group Limited | Extraterritorial | 1974 |
| Stockme AI Ltd | Information & communication | 2026 |
| Stoi Construct Ltd | Construction | 2025 |
| Stoke-On-Trent Theatres Limited | Arts & recreation | 1998 |
| Stoke-On-Trent Theatres Trust Limited | Arts & recreation | 2010 |
| Stone System of London Limited | Construction | 2001 |
| Stonecloud IT Limited | Financial services | 2016 |
| Stoneleigh Park Management Company Limited | Households | 1982 |
| Stones Inc Limited | Wholesale & retail | 2012 |
| Storage Technologies Ltd | Information & communication | 2014 |
| Store 2 Capital Ltd | Real estate | 2020 |
| Storeshield Limited | Professional & scientific | 1973 |
| Stories by SD Limited | Professional & scientific | 2023 |
| Stott Consulting and Research Limited | Professional & scientific | 2025 |
| Stovells FA Limited | Hospitality | 2018 |
| Strada Travel Ltd | Administrative & support | 2022 |
| Straight SIX Brewery Ltd | Manufacturing | 2020 |
| Strakt Consult Ltd | Professional & scientific | 2023 |
| Strange Business Limited | Professional & scientific | 2018 |
| Stratadata Limited | Mining & quarrying | 1992 |
| Strategic Imperatives Limited | Information & communication | 2005 |
| Strathcona Investments Limited | Administrative & support | 2018 |
| Straton Fire Ltd | Professional & scientific | 2014 |
| Streamline Animation Ltd | Information & communication | 2025 |
| Streamline Mortgage Services Limited | Financial services | 2006 |
| Streetsharp Ltd | Hospitality | 2015 |
| Strend Pro Ltd | Professional & scientific | 2024 |
| Stretchmasters Guildford Limited | Administrative & support | 2015 |
| Stridage Holdings Limited | Professional & scientific | 2011 |
| Stride Performance Ltd | Manufacturing | 2023 |
| Stroudgreen 24 Limited | Households | 2022 |
| Structures Consultants Limited | Professional & scientific | 2012 |
| Strutt Consulting Limited | Professional & scientific | 2010 |
| Stuart Fenn Property Services Ltd | Real estate | 2015 |
| Student House From Home Ltd | Real estate | 2022 |
| Studio 101 Horsell Limited | Other services | 2019 |
| Studio HAK Limited | Professional & scientific | 2023 |
| Studio Heathfield Limited | Professional & scientific | 2010 |
| Studio Landscaping Ltd | Administrative & support | 2021 |
| Studio Make-Up Services Limited | Other services | 2001 |
| Studio Sutton Limited | Professional & scientific | 2019 |
| Studland Green Management Limited | Real estate | 1989 |
| Study Chunks Ltd | Information & communication | 2025 |
| Study Connections Ltd | Administrative & support | 2012 |
| Styvin Studios Ltd | Professional & scientific | 2019 |
| Styx Fitness Ltd | Arts & recreation | 2025 |
| Subhanio Ltd | Wholesale & retail | 2025 |
| Subhub Nationwide Ltd | Administrative & support | 2024 |
| Success Medical Limited | Health & social care | 2025 |
| Suffolk Fast Foods Limited | Professional & scientific | 1984 |
| Sulltrans Ltd | Transport & logistics | 2025 |
| Sumitup Productions Limited | Information & communication | 2005 |
| Summerscales Performing Arts Ltd | Arts & recreation | 2024 |
| Sun Solutions Ltd | Information & communication | 2013 |
| Sunco Valeting Ltd | Administrative & support | 2020 |
| Sundunes Ltd | Construction | 2022 |
| Sunflora Properties Limited | Real estate | 2023 |
| Sunley Bath Limited | Construction | 2021 |
| Sunley Estates Limited | Construction | 1988 |
| Sunley Family Holding Limited | Financial services | 2020 |
| Sunley Family Limited | Financial services | 1987 |
| Sunley Group Ltd | Construction | 2006 |