| Engravebricks Limited | Other services | 2003 |
| Enhanced Fertility Ltd | Information & communication | 2020 |
| Enki Laboratories Ltd. | Information & communication | 2024 |
| Enkrypta Limited | Professional & scientific | 2018 |
| Enkrypta Ventures Ltd | Financial services | 2021 |
| Enlight Consultancy Services Limited | Information & communication | 2009 |
| Ennodia Limited | Professional & scientific | 2019 |
| Enterprise Business Consultancy Ltd | Information & communication | 2014 |
| Entrega Project Solutions Limited | Information & communication | 2019 |
| Enviro Tech (Europe) Limited | Manufacturing | 2001 |
| Environ (Kent) Limited | Construction | 2001 |
| Environment & Leisure Limited | Extraterritorial | 1990 |
| Environmental Controls Limited | Construction | 1998 |
| Envirosport Surfaces Limited | Construction | 2015 |
| Envision Advisory Services Ltd | Professional & scientific | 2015 |
| Envision Construction Ltd | Construction | 2020 |
| Envision Consultancy Services Limited | Other services | 2023 |
| Envision Roofing Services Ltd | Construction | 2022 |
| Enzo Bargains Ltd | Wholesale & retail | 2024 |
| Ephr Ltd | Administrative & support | 2024 |
| Epibiosafe Ltd | Professional & scientific | 2015 |
| Epic Barbers Products Limited | Other services | 2022 |
| Epic Home Developments Ltd | Real estate | 2016 |
| Epic Photo Co. Limited | Professional & scientific | 2017 |
| Eporsch Limited | Wholesale & retail | 2004 |
| Equartz Limited | Manufacturing | 2017 |
| Equi Technologies Limited | Information & communication | 2020 |
| Equimetenergysolutions Ltd | Wholesale & retail | 2026 |
| Equine Harmony Ltd | Agriculture & fishing | 2024 |
| Equipcode Limited | Professional & scientific | 1997 |
| Equitas Group Investments Ltd | Financial services | 2026 |
| ERA Bhardwaj Limited | Information & communication | 2015 |
| Erda Consulting Limited | Professional & scientific | 2010 |
| ERM RTM Company Limited | Households | 2026 |
| ERP Dynamix Ltd | Information & communication | 2024 |
| ERP GAS Services Ltd | Construction | 2018 |
| Errandslondon Ltd | Wholesale & retail | 2025 |
| Ervin Hall Limited | Professional & scientific | 2016 |
| ES Claims Centre Ltd | Financial services | 2026 |
| ES Fabrication and Engineering Services Ltd | Information & communication | 2024 |
| ESC Digital Media Limited | Information & communication | 2000 |
| Escape the City Limited | Other services | 2009 |
| Esdeclom Limited | Administrative & support | 2016 |
| Esimcrew Ltd | Information & communication | 2026 |
| Eskimo Express Ltd | Extraterritorial | 2004 |
| Eskimo Packaging Limited | Extraterritorial | 2014 |
| Eskimo Square Limited | Professional & scientific | 2004 |
| Esmet Limited | Professional & scientific | 2010 |
| Esports Talent Agency Ltd | Arts & recreation | 2025 |
| Essence Pilates Collective Ltd | Other services | 2025 |
| Essential Lettings Ltd | Real estate | 2007 |
| Essential Pet Foods Limited | Wholesale & retail | 2001 |
| EST EST Limited | Information & communication | 2015 |
| EST International Limited | Manufacturing | 2020 |
| Estazza Ltd | Information & communication | 2025 |
| Ethajo Ltd | Wholesale & retail | 2024 |
| Ethan Care Services Limited | Administrative & support | 2019 |
| Ethify Ltd | Administrative & support | 2020 |
| Ethika Healthcare Investments Limited | Professional & scientific | 2016 |
| Ethos Productions Ltd | Information & communication | 2015 |
| Etiko Consulting Ltd | Other services | 2011 |
| EU Business Services (E.B.S.) Limited | Professional & scientific | 2000 |
| EU Genya Ltd | Wholesale & retail | 2023 |
| EU Prestige Cleaning Ltd | Administrative & support | 2024 |
| Eumar Services Ltd | Transport & logistics | 2023 |
| Eurekalabs Limited | Information & communication | 2021 |
| Euro Petroleum Consultants Ltd | Professional & scientific | 1996 |
| Eurofinance Mortgages Limited | Professional & scientific | 2016 |
| Eurogate Limited | Professional & scientific | 1999 |
| Eurogate Logistics Limited | Transport & logistics | 1989 |
| Eurolux International Limited | Wholesale & retail | 1979 |
| Europa Provisions and Drinks Limited | Wholesale & retail | 2016 |
| European Regions Airline Association Limited | Other services | 2013 |
| European Source Ltd | Professional & scientific | 2004 |
| EV Swiftco Ltd | Transport & logistics | 2025 |
| Evans & Graham Maintenance Services Limited | Construction | 2008 |
| Evans Randall Europe LLP | | 2005 |
| Evans Tyre Services Limited | Other services | 2006 |
| Evensounds Limited | Professional & scientific | 2024 |
| Event Battalion Limited | Administrative & support | 2010 |
| Event Box Productions Ltd | Administrative & support | 2020 |
| Ever Blue Investment Limited | Real estate | 2017 |
| Everdant Ventures Ltd | Financial services | 2024 |
| Evergreen Sushi Ltd | Hospitality | 2024 |
| Evergreen Video Productions Ltd | Information & communication | 2024 |
| Everlith Ltd | Real estate | 2025 |
| Everton Plotholders Limited | Real estate | 2012 |
| Every Energy Ltd | Construction | 2024 |
| Every Jewels Ltd | Wholesale & retail | 2025 |
| Everyday Partners Ltd | Wholesale & retail | 2020 |
| Evesham Court Richmond Freehold Ltd | Households | 2025 |
| Evin Property Investments Ltd | Construction | 2010 |
| Evoke Capital Ltd | Financial services | 2025 |
| Evoke Digital Solutions Ltd | Information & communication | 2023 |
| Evoke Operations Ltd | Information & communication | 2025 |
| Evolution 2 Limited | Professional & scientific | 2011 |
| Evry Jewell Ltd | Wholesale & retail | 2022 |
| EWA Beauty Ltd | Other services | 2022 |
| Ewaan Ltd | Hospitality | 2023 |
| Ewbank's LLP | | 2016 |