| Little Grey Cells Publishing Services Limited | Information & communication | 2019 |
| Little Oak Pre-School (Witney) Limited | Education | 2010 |
| Little Oxbrew Limited | Manufacturing | 2015 |
| Little Oxford (NO.3) Management Company Limited | Households | 1993 |
| Little Oxford (NO.5) Management Company Limited | Households | 1993 |
| Little Oxford (NO.6) Management Company Limited | Households | 1993 |
| Little Snowflake Limited | Real estate | 2022 |
| Little YUM Limited | Hospitality | 2016 |
| Liva Healthcare UK Limited | Information & communication | 2017 |
| Live Holdings Limited | Arts & recreation | 2020 |
| Live IT Limited | Extraterritorial | 1998 |
| LIZ Evans Beauty Ltd | Other services | 2026 |
| Lizard King 28 Ltd | Wholesale & retail | 2025 |
| Ljaf Investments Ltd | Real estate | 2024 |
| LJB Masonry Contractors Limited | Construction | 2025 |
| LJO Holdings Ltd | Real estate | 2025 |
| LKG LS Property Limited | Households | 2022 |
| Lkmb Consulting Ltd | Professional & scientific | 2020 |
| LM Fleet Services Ltd | Professional & scientific | 2025 |
| Locker Technology Limited | Information & communication | 2019 |
| Locksley Marketing Ltd | Professional & scientific | 2025 |
| Loki Vince Limited | Construction | 2026 |
| London Fibre Group Ltd | Information & communication | 2019 |
| London Lover Productions Ltd | Information & communication | 2023 |
| London Placemaking Group Limited | Construction | 2024 |
| Longwell Education Limited | Education | 2023 |
| Looperties Ltd | Real estate | 2018 |
| Lordsbridge Limited | Real estate | 1963 |
| Lorentium Ltd | Professional & scientific | 2013 |
| Lost Art Productions Limited | Arts & recreation | 2023 |
| LOU LOU Creates Ltd | Professional & scientific | 2017 |
| Louise Cassettari Limited | Arts & recreation | 2015 |
| Love Dance Ltd | Education | 2025 |
| Love of MUD Ltd | Extraterritorial | 2014 |
| Love Travel Limited | Administrative & support | 2021 |
| Lovechild Studios Limited | Information & communication | 2023 |
| Lovegrove Engineering Consultancy Ltd | Professional & scientific | 2025 |
| LOW Power Radio Solutions Limited | Information & communication | 1985 |
| LOW Voltage UK Limited | Information & communication | 2010 |
| LP Hart Ltd | Real estate | 2013 |
| Luboka Media Limited | Information & communication | 2019 |
| Luca Recruits Ltd | Information & communication | 2024 |
| Lucilia Pharma Limited | Professional & scientific | 2012 |
| Lucky Seven Limited | Administrative & support | 2017 |
| Lucy Meakin Limited | Wholesale & retail | 2010 |
| Lucy the Mindset Coach Limited | Education | 2020 |
| Luke Anderson Hairdressing Limited | Other services | 2018 |
| Luke Collier Limited | Construction | 2013 |
| Lulex Limited | Extraterritorial | 2013 |
| Luminelle CIC | Arts & recreation | 2022 |
| Lumos Electrical Services Limited | Construction | 2013 |
| Lumos P.V. Power Systems Limited | Construction | 2022 |
| Lupus & Ferox Ltd | Financial services | 2026 |
| Lush Accounting Limited | Information & communication | 2022 |
| Luxe Creative Solutions Limited | Information & communication | 2024 |
| Luxury EYE Ltd | Other services | 2018 |
| Luxury Outdoor Living Limited | Wholesale & retail | 2017 |
| Luxury Pool Tables Limited | Wholesale & retail | 2013 |
| Lyall & Co Bakery Ltd | Manufacturing | 2020 |
| Lyall&Co Ltd | Hospitality | 2018 |
| Lyndhurst Holdings & Management Limited | Financial services | 2022 |
| Lyreal Limited | Information & communication | 2022 |
| L’Eabrows&Beauty Limited | Other services | 2026 |
| M & C Property Development & Maintenance Ltd | Construction | 2023 |
| M & M Waste Solutions Limited | Extraterritorial | 2012 |
| M B Electrics (2006) Limited | Construction | 2006 |
| M Chawda Ltd | Health & social care | 2015 |
| M Didcock Plumbing Limited | Construction | 2025 |
| M G I Taverns Limited | Hospitality | 2007 |
| M G Special Tuning Limited | Professional & scientific | 1988 |
| M J Pimm Investments Limited | Extraterritorial | 2015 |
| M L J Holdings Limited | Financial services | 2023 |
| M L J Property Investments Limited | Real estate | 2023 |
| M Sharp Solutions Ltd | Professional & scientific | 2024 |
| M&A Construction Witney Limited | Construction | 2023 |
| M&A UK Consultancy Limited | Professional & scientific | 2015 |
| M, S & O Ltd | Construction | 2026 |
| M-Solv Ltd | Manufacturing | 2004 |
| M. Everett Tree & Garden Limited | Administrative & support | 2003 |
| M. Relph (Sales) Limited | Wholesale & retail | 1967 |
| M.A.T.H (the PUB People) Ltd | Hospitality | 2024 |
| M.C.J.J. Limited | Arts & recreation | 2018 |
| M.E. Muller Limited | Other services | 1972 |
| M.Relph Limited | Other services | 1917 |
| M2C Energy Advisers Limited | Professional & scientific | 2015 |
| M2RG Bargains Ltd | Wholesale & retail | 2024 |
| M4DENT Ltd | Health & social care | 2020 |
| MAC Alarms Ltd | Administrative & support | 2017 |
| Mac's Garage ( Witney ) Limited | Wholesale & retail | 2005 |
| Maccaferri Ltd | Wholesale & retail | 1956 |
| Machowie Transport Limited | Transport & logistics | 2002 |
| Mackintom Limited | Professional & scientific | 2026 |
| Macklin Properties Limited | Real estate | 2022 |
| Macks Coating Services Ltd | Construction | 2022 |
| Maddocks Property Services Ltd | Administrative & support | 2009 |
| Made to Measure Computers Limited | Information & communication | 2008 |
| Madebymisfits Ltd | Information & communication | 2024 |
| Madeleydesignstudio Ltd | Information & communication | 2025 |
| Madison Walk (NO.2) Management Company Limited | Households | 2005 |
| Madison Walk Management Company Limited | Households | 2002 |