| Stephen Watson Contracts Ltd | Professional & scientific | 2017 |
| Steve Bennington Consulting Limited | Information & communication | 2014 |
| Stimpson Ltd | Health & social care | 2017 |
| Stockmans Holdings Limited | Real estate | 2018 |
| Stone&Steel Construction Ltd | Construction | 2025 |
| Stoneford Property Management Limited | Real estate | 2016 |
| Stovykla Ąžuolėlis CIC | Education | 2024 |
| Strattons Hotel Limited | Hospitality | 2002 |
| Strattons Liquid Waste Disposal Ltd. | Water & waste | 2002 |
| Strawberry Fields Narford Limited | Households | 2025 |
| Strawberry Occasions Ltd | Hospitality | 2021 |
| Stuart Holdings Limited | Financial services | 2019 |
| Stuart Transport Limited | Transport & logistics | 2007 |
| Stuart Young Education Consultants Ltd | Education | 2025 |
| Studio AUM Ltd | Information & communication | 2025 |
| STUDIO70SIX Ltd | Manufacturing | 2022 |
| Sublime Timing Ltd | Arts & recreation | 2022 |
| SUE SAN Ltd | Households | 2020 |
| Suge Ltd | Transport & logistics | 2021 |
| Sulehay Investment Limited | Extraterritorial | 2014 |
| Sumo Power Limited | Administrative & support | 2014 |
| Sun Luck Wisbech Limited | Hospitality | 2019 |
| Sunny Hottubs Ltd | Manufacturing | 2022 |
| Sunnyside Orchard Ltd | Agriculture & fishing | 2025 |
| Super Seal East Limited | Manufacturing | 2022 |
| Supercrete Groundworks Limited | Construction | 2000 |
| Supercrete Limited | Construction | 2009 |
| Superior Real Estate Ltd | Extraterritorial | 2024 |
| Support for Learning Limited | Education | 2003 |
| Surefire Electrical Ltd | Construction | 2025 |
| Surefire Engineering Group Ltd | Professional & scientific | 2025 |
| Surefire Heat Ltd | Construction | 2020 |
| Surefire Mechanical Ltd | Professional & scientific | 2025 |
| Surprise Flowers and Gifts Ltd | Wholesale & retail | 2025 |
| Surrey Hall Events Ltd | Arts & recreation | 2025 |
| Surveyors Advocates and Experts Limited | Professional & scientific | 2025 |
| Susie Piccaver Ltd | Arts & recreation | 2021 |
| Sussy Cazalet Design Limited | Professional & scientific | 2013 |
| Sutton Brokers Limited | Financial services | 2023 |
| Suzanne Archer Financial Consultancy Ltd | Professional & scientific | 2024 |
| SW & DJ Brown Ltd | Real estate | 2021 |
| Swann Manor Estates Ltd | Real estate | 2025 |
| Swerve Inc Limited | Information & communication | 2025 |
| Swift Building Company Ltd | Construction | 2010 |
| Synergy Health Coaching Ltd | Health & social care | 2025 |
| Syresham Engineering Services Limited | Administrative & support | 2003 |
| T & G Harrison Joinery Limited | Construction | 2002 |
| T & G Semper Electrical & Building Contractors Limited | Construction | 2015 |
| T & H Plant Repairs Limited | Other services | 1986 |
| T & I (Wisbech) Limited | Professional & scientific | 2007 |
| T & J Henfrey Contracting Limited | Administrative & support | 2016 |
| T & M Butchers Limited | Hospitality | 2010 |
| T & M Industries Limited | Manufacturing | 2012 |
| T Beckett Services Ltd | Construction | 2024 |
| T Chisholm & Sons Ltd | Wholesale & retail | 2022 |
| T Payne & Co Ltd | Real estate | 2014 |
| T S Services Wisbech Limited | Other services | 2024 |
| T&B Logistics Ltd | Transport & logistics | 2026 |
| T&H Farming Ltd | Agriculture & fishing | 2022 |
| T.P. & P.S. Lawrence Limited | Construction | 2006 |
| T.San Ltd | Wholesale & retail | 2017 |
| Tacos on the Go Ltd | Hospitality | 2026 |
| Tada Cleaning Services Ltd | Administrative & support | 2019 |
| Tailored Furniture Limited | Manufacturing | 2024 |
| Talking Shop Training Limited | Education | 2005 |
| Tall Trees Leisure Park Limited | Arts & recreation | 2005 |
| Tallon Trading Ltd | Construction | 2009 |
| TAM Engineering Services Limited | Manufacturing | 1994 |
| Tamar Computers (East Anglia) Limited | Information & communication | 2016 |
| Tamarin Bay Coffee House Ltd | Hospitality | 2023 |
| Tamworth Tearooms Limited | Hospitality | 2013 |
| Tangent Plant Hire Ltd | Construction | 2012 |
| Tangome Ltd | Professional & scientific | 2025 |
| Tankcare Engineering Limited | Manufacturing | 1998 |
| Tanning HUT Ltd | Other services | 2017 |
| Tanzanite Holdings Limited | Financial services | 2023 |
| Task Assist Ltd | Administrative & support | 2026 |
| Tasker’S Outdoor Living Ltd | Wholesale & retail | 2024 |
| Tatchell & Co.Limited | Agriculture & fishing | 1947 |
| Taylor'D Finance Limited | Financial services | 2026 |
| Taylored Moments Limited | Professional & scientific | 2025 |
| Taylors Reclaims Limited | Administrative & support | 2002 |
| TBL Trans Ltd | Transport & logistics | 2023 |
| TCB Property Ltd | Real estate | 2024 |
| Tcfibreoptics Ltd | Professional & scientific | 2023 |
| Team Gems Cambridgeshire Ltd | Administrative & support | 2024 |
| Team Gems Commercial Limited | Administrative & support | 2016 |
| Team Gems Limited | Administrative & support | 2014 |
| Team Gems Norfolk Ltd | Administrative & support | 2024 |
| Technocode Ltd | Other services | 2025 |
| Telenova Limited | Information & communication | 2006 |
| Tengaanii Holdings (UK) Limited | Financial services | 2018 |
| Terelinck UK Ltd | Information & communication | 2025 |
| Terrington Fish Bar Ltd | Hospitality | 2019 |
| Terrys Diner Limited | Hospitality | 2002 |
| Testermans Limited | Wholesale & retail | 2017 |
| TF Motorcycles Limited | Wholesale & retail | 2021 |
| TG Storage & Transport Ltd | Transport & logistics | 2023 |
| Tgnd Limited | Hospitality | 2024 |
| Thai Wellness Cambridgeshire Limited | Other services | 2024 |