| E.P Plumbing &Heating Ltd | Water & waste | 2014 |
| E.S.A. Home Improvements Ltd | Construction | 2019 |
| E91 Home Improvement Ltd | Construction | 2025 |
| EAC Solutions Ltd | Professional & scientific | 2022 |
| Eacts Publishing Limited | Information & communication | 2007 |
| Eacts Trading Company Limited | Other services | 2000 |
| Eagerstone Limited | Wholesale & retail | 1994 |
| Eagleshift Digital Ltd | Manufacturing | 2024 |
| EAR Candy Studios Limited | Extraterritorial | 2006 |
| Earth AGE Ltd | Wholesale & retail | 2024 |
| East Meets West Productions Limited | Information & communication | 2019 |
| Easton Street Properties Limited | Construction | 2021 |
| Easy 2 Rent Ltd | Real estate | 2023 |
| Easyramps.Co.Uk Limited | Manufacturing | 2008 |
| Eaves Property Management Services Limited | Real estate | 2018 |
| Echo Consultancy Services Limited | Professional & scientific | 2019 |
| Echo Creative Services Limited | Professional & scientific | 2018 |
| ECL Contracts Limited | Extraterritorial | 1992 |
| ECL Investments Limited | Extraterritorial | 2009 |
| Eco Party Ltd | Wholesale & retail | 2021 |
| ED Banditt Ltd | Arts & recreation | 2022 |
| EDC Home Ltd | Real estate | 2025 |
| Edge Partners Limited | Professional & scientific | 2019 |
| Edinburgh Gardens Residents' Association Limited | Households | 1976 |
| Edinburgh George Street Hotel Opco Limited | Hospitality | 2018 |
| Edmonds & Sons Plumbing, Heating & Bathrooms Limited | Construction | 2026 |
| EDUCATE2GETHER Ltd | Education | 2022 |
| Education in England Limited | Education | 2020 |
| Education Partners Limited | Real estate | 2023 |
| Eduvision Consulting Limited | Administrative & support | 2023 |
| Edward MAN Global Ltd | Wholesale & retail | 2022 |
| EE First House Limited | Real estate | 2025 |
| Eepoint Ltd | Professional & scientific | 2020 |
| Effective Edge Limited | Professional & scientific | 2023 |
| EG: Initiatives Limited | Professional & scientific | 1996 |
| EGS Management Ltd | Wholesale & retail | 2022 |
| Eighteen Travel Ltd | Administrative & support | 2024 |
| Eighteentwentysix Limited | Arts & recreation | 2008 |
| Eighth Property Investment Limited | Real estate | 2017 |
| Eindhan Ltd | Information & communication | 2014 |
| Eitlean AI Limited | Education | 2023 |
| EJS Property Investment Limited | Real estate | 2019 |
| EJS Scenery Ltd | Construction | 2017 |
| EK Noor Properties Ltd | Real estate | 2025 |
| Ekgr Ltd | Other services | 2014 |
| EKO Chem Limited | Wholesale & retail | 2009 |
| Electric Gate Repair London Ltd | Manufacturing | 2016 |
| Electric Vehicle Ecosystem Ltd | Administrative & support | 2021 |
| Elements Eight RUM Company Limited | Wholesale & retail | 2005 |
| Eleo Digital Limited | Information & communication | 2024 |
| Elevated Axis Ltd | Professional & scientific | 2016 |
| Elia Builders Ltd | Construction | 2025 |
| Eliox Healthcare Limited | Wholesale & retail | 2026 |
| Eliox Pharma Limited | Wholesale & retail | 2025 |
| Eliox UK Limited | Wholesale & retail | 2016 |
| Elisha Properties Limited | Real estate | 2019 |
| Elisha Property Services Ltd | Real estate | 2023 |
| Elite Autos and Bodyshop Limited | Wholesale & retail | 2018 |
| Elite Chauffeuring Private Ltd | Transport & logistics | 2026 |
| Elite Housekeeping Ltd | Administrative & support | 2022 |
| Elite Rendering Solutions Limited | Construction | 2025 |
| Elite Roofing and Building Limited | Construction | 2025 |
| Elite Signs & Graphic Displays Limited | Professional & scientific | 1998 |
| Elite Tutors Limited | Education | 2002 |
| Elite Windows (Reading) Limited | Wholesale & retail | 2010 |
| Elizabeth Rose Homes Limited | Construction | 2020 |
| Elizabeth Sanders Limited | Professional & scientific | 2011 |
| Elless Solutions Limited | Professional & scientific | 2016 |
| Elliott-Ross Hamper Company Limited | Wholesale & retail | 2021 |
| Ellis Smith Projects Ltd | Wholesale & retail | 2025 |
| Ellmorsa Limited | Professional & scientific | 2013 |
| Elmodesham Limited | Households | 1987 |
| Elmwood Gate Management Company Limited | Households | 2019 |
| Elsewhere Estate Agents Ltd | Real estate | 2017 |
| Elswick Energy Limited | Mining & quarrying | 2013 |
| Elsy Homes Ltd | Real estate | 2022 |
| Elysian Code Limited | Information & communication | 2016 |
| Emcor Real Estate Ltd | Real estate | 2025 |
| Emergency Services & Security Uniforms and Bags Ltd | Manufacturing | 2025 |
| Emily & Emine Limited | Other services | 2011 |
| Emineo Management Company Limited | Households | 2004 |
| EMM JAY Services Ltd | Transport & logistics | 2020 |
| Emma Cook Associates Limited | Professional & scientific | 2007 |
| Emma Kenny Browne Ltd | Professional & scientific | 2026 |
| Emma Martin Training & Aesthetics Ltd | Other services | 2019 |
| EN Route International Limited | Hospitality | 2002 |
| Energy Contract Options Ltd | Professional & scientific | 2019 |
| Energy Contract Renewals Ltd | Professional & scientific | 2016 |
| Energy for Tomorrow | Administrative & support | 2007 |
| Energyfund Limited | Extraterritorial | 2008 |
| Enerscope Limited | Information & communication | 2008 |
| Enforce-Logic Limited | Wholesale & retail | 2005 |
| Engaging Brands Ltd | Manufacturing | 2025 |
| Englemere Management Company Limited | Households | 2015 |
| Enlightening Technologies Limited | Information & communication | 2005 |
| Enovo Retail Limited | Wholesale & retail | 2019 |
| Ensleek Limited | Wholesale & retail | 2025 |
| Enstone Electrical Services Ltd | Construction | 2014 |
| Enterprise LAB Limited | Education | 2011 |
| Entertainment Rights Management Limited | Professional & scientific | 2005 |