| Film Manchester Limited | Professional & scientific | 2016 |
| Finance 365 Limited | Financial services | 2013 |
| Finance, Capital and Wealth Group Limited | Financial services | 2025 |
| Financial Cartography Ltd | Professional & scientific | 2026 |
| Financial Project Management Limited | Administrative & support | 2015 |
| Fincompare Ltd | Wholesale & retail | 2025 |
| Find My Funding Limited | Administrative & support | 2024 |
| Find My Group Limited | Financial services | 2026 |
| Find My Recruitment Funding Limited | Administrative & support | 2021 |
| Finlays Yard Management Company Limited | Households | 2022 |
| Finselect Ltd | Administrative & support | 2016 |
| Finstra Limited | Administrative & support | 2025 |
| Fintectm Ltd | Information & communication | 2023 |
| Fiore Medical Center Ltd | Health & social care | 2016 |
| Fiorucci Hair Ltd | Other services | 2025 |
| Firdale Park East Apartments Management Company (NO.3) Limited | Households | 1986 |
| Fire and Security Tameside Limited | Professional & scientific | 2023 |
| Fire Finco Limited | Financial services | 2021 |
| Fire Hose Reels Direct Ltd | Public administration | 2019 |
| Fireworld UK Limited | Professional & scientific | 2024 |
| First 4 Consulting Ltd | Professional & scientific | 2022 |
| First Financial Management Limited | Other services | 2016 |
| First for Bars & Restaurants Limited | Hospitality | 2011 |
| Fisichella Ltd | Wholesale & retail | 2021 |
| Fit Delis Ltd | Hospitality | 2016 |
| Fitness Manchester Limited | Arts & recreation | 2024 |
| Fitzpatrick Medical Limited | Health & social care | 2023 |
| Five Dees Group Ltd | Transport & logistics | 2025 |
| FIX My Shoulder Limited | Health & social care | 2019 |
| Fizz Guru Limited | Wholesale & retail | 2014 |
| FJE Trading Ltd | Financial services | 2024 |
| FJM HR Legal Services Limited | Professional & scientific | 2017 |
| FK Medical Ltd | Health & social care | 2018 |
| Fleetness 701 Limited | Administrative & support | 2010 |
| Flexebee Ltd. | Education | 2016 |
| Flexi Network Ltd | Financial services | 2020 |
| Flexible Solutionz Ltd | Administrative & support | 2002 |
| Flexiss Group Limited | Real estate | 2020 |
| Flexiss Management Services Ltd | Real estate | 2019 |
| Flexiss Projects Ltd | Real estate | 2022 |
| Float Therapy Ltd | Health & social care | 2021 |
| Floryan Consult Limited | Professional & scientific | 2008 |
| Flowtech Fluidpower PLC | Professional & scientific | 2014 |
| Flowtogether Ltd | Professional & scientific | 2025 |
| Fluffy Carpets Ltd | Extraterritorial | 2015 |
| Fluid Start-Up Ltd | Financial services | 2022 |
| Fluidpower Group Services UK Limited | Manufacturing | 1968 |
| Fluidpower Group UK Limited | Wholesale & retail | 1982 |
| Fluidpower MIP Limited | Professional & scientific | 2014 |
| Fluidpower Shared Services Limited | Financial services | 2004 |
| Flvr Digital Limited | Professional & scientific | 2019 |
| Flying EYE Images Ltd | Professional & scientific | 2018 |
| Flynn Garden Services Limited | Administrative & support | 2003 |
| FM IT Solutions Ltd | Information & communication | 2019 |
| FM Plastic Surgery Limited | Health & social care | 2023 |
| FOB D (UK) Limited | Professional & scientific | 2018 |
| Focus 5 Recruitment Ltd | Professional & scientific | 2018 |
| Focus Analysts Ltd | Professional & scientific | 2016 |
| Focus First Adhd Limited | Health & social care | 2025 |
| Food Alert Limited | Hospitality | 1990 |
| Food My Way (Handforth) Limited | Hospitality | 2014 |
| Food My Way (Summerfields) Limited | Hospitality | 2015 |
| Foodity Limited | Hospitality | 2023 |
| Foot & Ankle DOC Limited | Health & social care | 2017 |
| Football Family Limited | Arts & recreation | 2018 |
| Football Flashbacks Ltd | Wholesale & retail | 2018 |
| Football Futures Group Limited | Education | 2022 |
| Football Futures Limited | Education | 2023 |
| Footfeel UK Limited | Arts & recreation | 2023 |
| Footsquare Limited | Wholesale & retail | 2018 |
| Footwear Technical Services Limited | Other services | 2014 |
| Forensic Neurosciences Limited | Health & social care | 2004 |
| Forensic Psychiatry Reports Limited | Health & social care | 2022 |
| Foresight Wealth Preservation LLP | | 2018 |
| Forest Grange (Swadlincote) Management Company Limited | Households | 2015 |
| Forgerie Logistics Ltd | Transport & logistics | 2020 |
| Forjam Ltd | Information & communication | 2025 |
| Forte and Belle Ltd | Real estate | 2026 |
| Forthmerry Estates Ltd | Real estate | 2008 |
| Fortiva Group Ltd | Financial services | 2024 |
| Fortiva Limited | Professional & scientific | 2023 |
| Fortiva US Limited | Administrative & support | 2024 |
| Forty SIX Studio Ltd | Professional & scientific | 2026 |
| FORTY8 Design Ltd | Professional & scientific | 2018 |
| Foundry Intelligence Ltd | Information & communication | 2026 |
| Four Seasons Trees & Gardens Limited | Administrative & support | 2016 |
| Four Winds Medical Services Limited | Health & social care | 2019 |
| Fourcompany UK Ltd | Wholesale & retail | 2026 |
| Foyle Wilson Interior Projects Ltd | Construction | 2025 |
| FP Blinds Limited | Wholesale & retail | 2024 |
| FPL Ltd | Arts & recreation | 2024 |
| FPL Roofing Ltd | Construction | 2025 |
| Fractal Knowledge Limited | Information & communication | 2019 |
| Fractional Accountancy Services Ltd | Administrative & support | 2025 |
| Francis Bradshaw Consulting Limited | Professional & scientific | 2023 |
| Frangos Manchester Ltd | Professional & scientific | 2019 |
| Frank B Thornton Limited | Professional & scientific | 2008 |
| Frank Brewster Ltd | Professional & scientific | 2025 |
| Frank Godley Ltd | Wholesale & retail | 2025 |
| Franklin EV Limited | Energy | 2015 |