| Dicedigitalstudio Ltd | Professional & scientific | 2021 |
| Dida Arts CIC | Information & communication | 2025 |
| Digital Plan Builders Ltd | Construction | 2024 |
| Digital Print Products Ltd | Manufacturing | 2022 |
| Digixtraa Ltd | Information & communication | 2026 |
| Dilbag Ltd | Real estate | 2025 |
| Direct Food Solution Limited | Manufacturing | 2009 |
| Discipline & Delight Ltd | Extraterritorial | 2025 |
| Dixon Industrial Roofing Limited | | 1978 |
| Dizzy Kidz (New) Ltd | Arts & recreation | 2023 |
| DJM Investments Limited | Administrative & support | 2009 |
| DK Automotive Ltd | Financial services | 2017 |
| DK Car Sales Limited | Wholesale & retail | 2022 |
| DK Double Glazing (Willenhall) Ltd | Manufacturing | 2012 |
| DK Tuning Limited | Wholesale & retail | 2016 |
| Dlct Food Ltd | Hospitality | 2026 |
| DLM Electrical Services (Midlands) Limited | Construction | 2015 |
| DMC Carpentry Services Limited | Construction | 2017 |
| DMC Profiles Ltd | Manufacturing | 2016 |
| DMP Films Ltd | Other services | 2017 |
| Dolman Enterprises Limited | Hospitality | 2025 |
| DOM Miles Builders Limited | Construction | 2025 |
| Domi Trans Services Ltd | Transport & logistics | 2024 |
| Domson Midlands Ltd | Wholesale & retail | 2013 |
| Domy-Transport Ltd | Transport & logistics | 2018 |
| Donarc Facades Limited | Construction | 2018 |
| DOOR2FIT Ltd | Construction | 2025 |
| Dosanjh Transport Limited | Transport & logistics | 2015 |
| DOT Care Solutions Ltd | Health & social care | 2025 |
| Doubleluckchinesetakeaway Ltd | Hospitality | 2026 |
| DPO Haulage Ltd | Transport & logistics | 2024 |
| DR Bar Ltd | Real estate | 2022 |
| DR Barooq Holdings Ltd | Financial services | 2025 |
| DR Baruk Ventures Limited | Real estate | 2025 |
| Dream Homes UK Construction Ltd | Construction | 2021 |
| Dream Plan Builder Ltd | Construction | 2019 |
| Dreamy & Creamy Cakebyjas Ltd | Wholesale & retail | 2024 |
| Drew Saunders Ltd | Construction | 2020 |
| Driveline Technology Limited | Professional & scientific | 2002 |
| Driven Group Limited | Health & social care | 2018 |
| Driving Excellence Limited | Transport & logistics | 2015 |
| Drlb Investments Limited | Real estate | 2018 |
| Drop 247 Ltd | Transport & logistics | 2025 |
| DSF Enterprises Ltd | Wholesale & retail | 2017 |
| Dsiennak Ltd | Administrative & support | 2021 |
| Dsinterpriseltd Limited | Construction | 2022 |
| DSK Transport Ltd | Transport & logistics | 2019 |
| DSS Transport Ltd | Transport & logistics | 2018 |
| DTL School of Motoring Ltd | Education | 2025 |
| DTR3 Training Limited | Administrative & support | 2013 |
| Dubez Painter & Decorator Ltd | Administrative & support | 2017 |
| Dunham Property Letting & Services Limited | Administrative & support | 2023 |
| Dwello Mortgages Limited | Financial services | 2022 |
| DWF Complex Solutions Limited | Wholesale & retail | 2019 |
| Dynamai Property Services Ltd | Real estate | 2025 |
| Dynamics Transport Limited | Transport & logistics | 2026 |
| E & T Services Ltd | Wholesale & retail | 2019 |
| E-Retail Store Limited | Wholesale & retail | 2025 |
| E-Tech Recruitment Limited | Administrative & support | 2002 |
| E. L. Mccarthy Limited | Health & social care | 2021 |
| Eaglelion Services Limited | Health & social care | 2023 |
| Early Years Education Centre Eyec Limited | Health & social care | 2015 |
| Easpire Goods Ltd | Wholesale & retail | 2026 |
| Easy Homes Midlands Ltd | Real estate | 2025 |
| Easybuild Limited | Construction | 2019 |
| EASYCOURIER4U Ltd | Transport & logistics | 2024 |
| Easywaycourier Ltd | Transport & logistics | 2023 |
| Ebenezer Care Solutions Limited | Health & social care | 2014 |
| Ebenezer.Hb Ltd | Other services | 2015 |
| EC Enhance Clinic Ltd | Other services | 2024 |
| Echarisma Ltd. | Information & communication | 2013 |
| Eclipse Painting Limited | Construction | 2018 |
| Eclipse Partners Group Ltd | Real estate | 2024 |
| Ed-Shir Global International Limited | Manufacturing | 2024 |
| Eddy & Greg UK Limited | Information & communication | 2014 |
| Eden Legal Services Limited | Professional & scientific | 2017 |
| Edit Education Limited | Education | 2023 |
| Education Business Hub Limited | Financial services | 2019 |
| Edward Elwell Limited | Extraterritorial | 1902 |
| Efdit Music Limited | Information & communication | 1994 |
| Eggless Cake Shop Willenhall Limited | Manufacturing | 2015 |
| Elcorp Capital Ltd | Real estate | 2020 |
| Elcorp Ltd | Administrative & support | 2011 |
| Electro Fixings Ltd | Energy | 2019 |
| Elgin Services Ltd | Wholesale & retail | 2025 |
| Eliora Global Ltd | Information & communication | 2023 |
| Elite Care Holdings Ltd | Financial services | 2024 |
| Elite Care Properties Ltd | Real estate | 2024 |
| Elite Computers Ltd | Wholesale & retail | 2025 |
| Elite Driving Centre Ltd | Wholesale & retail | 2013 |
| Elite Kitchen Canopies Ltd | Manufacturing | 2025 |
| Eltham High Street (AGG7) Limited | Real estate | 2013 |
| Emanate Wellness Co. Ltd | Wholesale & retail | 2026 |
| Employment Law in Action Limited | Administrative & support | 2007 |
| Enablement Care Limited | Health & social care | 2024 |
| Endcliffe Holdings Limited | Financial services | 2018 |
| Enefer Contracts Limited | Transport & logistics | 2016 |
| Enfield High Street (AGG10) Limited | Real estate | 2013 |
| Enfield High Street (AGG11) Limited | Real estate | 2013 |
| Enfield High Street (AGG12) Limited | Real estate | 2013 |