| DAZ Media Ltd | Professional & scientific | 2020 |
| DB DIY Services Ltd | Construction | 2022 |
| Dbillions Ltd | Wholesale & retail | 2024 |
| Dbrothers Ltd | Hospitality | 2024 |
| Dcomhero Ltd | Information & communication | 2025 |
| DE Control Systems Ltd | Information & communication | 2025 |
| DE Mello HR Consulting Limited | Professional & scientific | 2017 |
| Deenova UK Limited | Health & social care | 2011 |
| Deep Brar Ltd | Transport & logistics | 2018 |
| Deepa Fashions Ltd | Wholesale & retail | 2008 |
| Deepdale Demolition & Groundwork Ltd | Construction | 2025 |
| Denture Care Clinic Limited | Wholesale & retail | 2012 |
| Dermis Diva Ltd | Wholesale & retail | 2025 |
| DG Buying & Sourcing Solutions Ltd | Professional & scientific | 2024 |
| DG Films Ltd | Information & communication | 1990 |
| DGM Property Development Ltd | Real estate | 2024 |
| DHC Mali Ltd | Real estate | 2024 |
| Dhillons Cars (Leicester) Ltd | Wholesale & retail | 2015 |
| Diamond CUT Cleaning Services Ltd | Administrative & support | 2025 |
| Diamond Occasions Limited | Other services | 2015 |
| Diangs Holdings Ltd | Financial services | 2025 |
| Digi TEL Associates Ltd | Wholesale & retail | 2020 |
| Digisolutions Limited | Wholesale & retail | 2008 |
| Dinted Ltd | Wholesale & retail | 2025 |
| Discovery Knitting.Co.Uk Ltd | Manufacturing | 2020 |
| Discovery to Product Ltd | Professional & scientific | 2023 |
| Disney Transport Ltd | Transport & logistics | 2025 |
| Divine Nights Limited | Wholesale & retail | 2024 |
| Divinefurniture Ltd | Wholesale & retail | 2025 |
| DJR Control Systems Ltd | Information & communication | 2008 |
| DMB Projects Ltd | Construction | 2021 |
| DMD Pipelines Limited | Construction | 2019 |
| Dmntradingltd Ltd | Wholesale & retail | 2025 |
| DMO Construction Ltd | Construction | 2020 |
| DMP Transport Limited | Transport & logistics | 2014 |
| Docare Support and Development Ltd | Administrative & support | 2018 |
| Dollybetsyevents Ltd | Hospitality | 2022 |
| Domlas Ltd | Information & communication | 2011 |
| Domlyn Ltd | Health & social care | 2022 |
| Donason Services Limited | Administrative & support | 2019 |
| DPR Haulage Ltd | Transport & logistics | 2025 |
| DPS Cleaning Ltd | Administrative & support | 2022 |
| DR F Apaloo Ltd | Health & social care | 2013 |
| DR Janet Menna Ltd | Education | 2025 |
| DR Kavi Medical Services Limited | Health & social care | 2025 |
| DR LAM Aesthetics Ltd | Health & social care | 2024 |
| DR M Zanoun Ltd | Health & social care | 2021 |
| DRA & Sons Ltd | Financial services | 2024 |
| Draper Commercial Limited | Real estate | 1946 |
| DRC Optics Limited | Health & social care | 2019 |
| Dreams Coffee Ltd | Hospitality | 2021 |
| Dropx Ltd | Transport & logistics | 2025 |
| DRT Foods Limited | Wholesale & retail | 2025 |
| DS Project Controls Limited | Professional & scientific | 2013 |
| DSC Auto Electrics Ltd | Administrative & support | 2017 |
| DSK Care Ltd | Other services | 2018 |
| DSR Domestics Limited | Wholesale & retail | 2019 |
| DT Mckenzie Investment Ltd | Other services | 2021 |
| DTE Development Limited | Professional & scientific | 2017 |
| Dubai Lunch Ltd | Hospitality | 2025 |
| Dunamist FM and Logistics Ltd | Transport & logistics | 2021 |
| Dyal Convenience Ltd | Wholesale & retail | 2023 |
| E&F Transport Ltd | Transport & logistics | 2023 |
| E-Pad Developments Ltd | Construction | 2026 |
| E.M.Inspection Company Limited | Professional & scientific | 1965 |
| EAP Global Ltd | Wholesale & retail | 2018 |
| East Midlands Mobility Ltd | Wholesale & retail | 2021 |
| East Midlands Reactive Maintenance Limited | Construction | 2014 |
| East Midlands Tiling Limited | Construction | 2019 |
| EC & HC Properties Ltd | Real estate | 2025 |
| Eco Sanctuary Limited | Construction | 2025 |
| Ecoclimate Homes Ltd | Construction | 2022 |
| Eden Women of Impact CIC | Administrative & support | 2025 |
| EDG Fitness Ltd | Health & social care | 2015 |
| Edgar E-Commerce Ltd | Wholesale & retail | 2025 |
| Edible Labels Ltd | Manufacturing | 2024 |
| Eesa Logistics and Transport Ltd | Transport & logistics | 2023 |
| EFC Haulage Ltd | Transport & logistics | 2021 |
| Ejgd Consulting Ltd | Financial services | 2023 |
| Ekadanta Properties Limited | Real estate | 2021 |
| Electronic Modular Solutions Limited | Information & communication | 1993 |
| Elegant Dressing Ltd | Manufacturing | 2025 |
| Elegant Products (UK) Limited | Wholesale & retail | 2009 |
| Elite Smiles Services Ltd | Health & social care | 2015 |
| Ellies Hair & Extensions Limited | Other services | 2023 |
| Elmestone Ltd | Water & waste | 2024 |
| Elysian Essence Ltd | Health & social care | 2025 |
| EM Oils Ltd | Transport & logistics | 2015 |
| Emaan Taxis Ltd | Transport & logistics | 2022 |
| Emaziz Limited | Health & social care | 2013 |
| Emergency Plumbers Leicestershire Ltd | Construction | 2026 |
| EMK Logistics Ltd | Transport & logistics | 2021 |
| Empirova Ltd | Wholesale & retail | 2026 |
| Energy Costcutters Limited | Wholesale & retail | 2016 |
| Engineered Copy Ltd | Professional & scientific | 2020 |
| Enilem Bookkeeping Ltd | Wholesale & retail | 2021 |
| Enreta Direct Limited | Wholesale & retail | 2018 |
| Enviropal Ltd | Manufacturing | 2025 |
| Eskarda Sundein Ltd | Wholesale & retail | 2021 |
| Esme Louise Cleaning Services Ltd | Administrative & support | 2026 |