| Douglas Valley Roofline Ltd | Construction | 2008 |
| Dove Online Ltd | Wholesale & retail | 2022 |
| Dowdeswell Design Limited | Professional & scientific | 1992 |
| Dowling & Baker Properties Ltd | Real estate | 2023 |
| Down to Earth Tree Surgeons Ltd | Administrative & support | 2026 |
| DP Drilling Ltd | Construction | 2012 |
| DPA Cloud Services Ltd | Information & communication | 2025 |
| DPA R&D Ltd | Information & communication | 2025 |
| Dpathfinda Group Limited | Wholesale & retail | 2023 |
| DPB Composites & Leak Sealing Ltd | Professional & scientific | 2023 |
| DPB Plumbing and Bathrooms Ltd | Construction | 2026 |
| DPM Electrical Ltd | Construction | 2015 |
| DPP Installations Ltd | Construction | 2018 |
| DPS Plumbing & Heating NW Ltd | Construction | 2018 |
| Dpsi Group Ltd | Administrative & support | 2021 |
| DPV Project Management Ltd | Construction | 2021 |
| DR a Fairhurst Medical Services Limited | Health & social care | 2018 |
| DR Finch Locums Limited | Health & social care | 2014 |
| DR Safety Consultants Limited | Administrative & support | 2023 |
| DR. Franz Walter Consult LLP | | 2025 |
| DR. Seedam Ltd | Administrative & support | 2017 |
| Dragon Hydraulic Systems Limited | Wholesale & retail | 2008 |
| Dragon Hydraulics Limited | Manufacturing | 1998 |
| Dragon-Phoenix Ascended Ltd | Information & communication | 2024 |
| Dragonfly Care Group Ltd | Health & social care | 2026 |
| Drainforce Solutions Ltd | Administrative & support | 2024 |
| Drainrite Environmental Services Limited | Water & waste | 2000 |
| Drainrite Plant Services Limited | Administrative & support | 2000 |
| Drama Tech UK Ltd | Arts & recreation | 2023 |
| Dranadis | Professional & scientific | 2025 |
| DRB Properties Ltd | Real estate | 2025 |
| Drcm Properties Limited | Real estate | 2024 |
| Dream Carpets & Flooring Limited | Wholesale & retail | 2025 |
| Dreamsnowalive Ltd | Professional & scientific | 2025 |
| Dreamtruck Ltd | Transport & logistics | 2024 |
| Drew(Wigan) Limited | Extraterritorial | 2026 |
| Drip Drops Ltd | Wholesale & retail | 2025 |
| Drive Solutions (NW) Limited | Other services | 2015 |
| Drive UP Self Store Ltd | Transport & logistics | 2019 |
| Drive With Callum Ltd | Education | 2024 |
| Driveable C.I.C. | Education | 2025 |
| Driving Instructor Limited | Education | 2020 |
| DRM Electrical Limited | Construction | 2002 |
| DRM Financial Consultants Limited | Professional & scientific | 2019 |
| Dropshop NW Ltd | Wholesale & retail | 2023 |
| Drrb LCJ Limited | Hospitality | 2025 |
| Drum One Limited | Wholesale & retail | 2017 |
| Drute Ltd | Wholesale & retail | 2023 |
| DRV Autos DC Ltd | Manufacturing | 2024 |
| DS Art Design Limited | Construction | 2019 |
| DS Group NW Limited | Professional & scientific | 2025 |
| DS23 Properties Ltd | Real estate | 2025 |
| DSA Bespoke Property Limited | Hospitality | 2023 |
| DSG (NW) Limited | Extraterritorial | 2014 |
| Dsgw Properties Ltd | Households | 2024 |
| DSW Fleet Support Limited | Administrative & support | 2018 |
| DT Agencies Ltd | Wholesale & retail | 2017 |
| DT Design Solutions Ltd | Professional & scientific | 2024 |
| DTC (Salford) Limited | Construction | 2020 |
| DTG Professional Services Limited | Education | 2022 |
| DTH Decorating Contractors Limited | Construction | 2019 |
| DTM Drainage Solutions Limited | Water & waste | 2014 |
| DTU Solutions Ltd | Wholesale & retail | 2022 |
| Dtwigan Limited | Hospitality | 2025 |
| Dual Inspirations Ltd | Wholesale & retail | 2020 |
| Duality Solutions Ltd | Information & communication | 2008 |
| Duamor Building Surveying Ltd | Construction | 2014 |
| Duddon Projects Limited | Construction | 2012 |
| Dukewell Precision Limited | Manufacturing | 2016 |
| Duncan's Property Consultants Limited | Professional & scientific | 2020 |
| Dunham Property Consultants Ltd | Professional & scientific | 2022 |
| Dunholm Properties Limited | Real estate | 2023 |
| Dunn Aviation Ltd | Transport & logistics | 2014 |
| Dunn-Metcalfe Limited | Administrative & support | 2022 |
| Duronel Ltd | Professional & scientific | 2026 |
| Durose and Gourlay Ltd. | Construction | 2010 |
| Duty to Thrive Limited | Professional & scientific | 2026 |
| DV Trans Ltd | Transport & logistics | 2019 |
| Dvaa Properties Limited | Real estate | 2018 |
| Dvsn Automotive Ltd | Wholesale & retail | 2024 |
| DW Rail ARB Ltd | Agriculture & fishing | 2024 |
| DWK Drylining Projects Ltd | Construction | 2024 |
| DWR Mechanical Services Ltd | Professional & scientific | 2017 |
| DWR Subsea Ltd | Manufacturing | 2022 |
| DWU Consultancy Ltd | Professional & scientific | 2021 |
| Dwyer and Sons Limited | Real estate | 2024 |
| Dwyer Matthews Construction Limited | Construction | 2023 |
| DX Market Ltd | Wholesale & retail | 2025 |
| DXD Transport Ltd | Transport & logistics | 2021 |
| Dylan Mascord Coaching Limited | Education | 2024 |
| Dylan's Power Washing and Maintenance Ltd | Administrative & support | 2026 |
| Dynamic Auto Sales Ltd | Wholesale & retail | 2026 |
| Dynamic Building Group Ltd | Extraterritorial | 2022 |
| Dynamic Micro Systems Ltd | Other services | 2015 |
| Dynamic Vehicle Rental Limited | Administrative & support | 2018 |
| Dynamics 365 North West Ltd | Other services | 2019 |
| Dynamique Haulage Ltd | Transport & logistics | 2026 |
| Dysania Ltd | Real estate | 2018 |
| Dyson Bricklaying Limited | Construction | 2016 |
| E & G Developments Limited | Construction | 2017 |