| Dealr Ltd | Information & communication | 2025 |
| Deals on 4 Wheels Ltd | Wholesale & retail | 2025 |
| Dean Group Limited | Professional & scientific | 2023 |
| Dean Residential Properties Limited | Real estate | 2023 |
| Deano Music Limited | Arts & recreation | 2010 |
| DEBOSZ25102022 Ltd | Transport & logistics | 2022 |
| Debt Plans Direct Ltd | Financial services | 2017 |
| Debtfocus Business Recovery & Insolvency Limited | Financial services | 2009 |
| DEC Office Properties Ltd | Real estate | 2019 |
| Decafy AI Limited | Information & communication | 2024 |
| Decafy Ltd | Information & communication | 2014 |
| Deck Space Ltd | Construction | 2024 |
| Dedo Group Ltd | Professional & scientific | 2025 |
| DEE Baylis Limited | Wholesale & retail | 1983 |
| DEE Thai Foods Ltd | Wholesale & retail | 2017 |
| Dee's Driveways Limited | Construction | 2010 |
| Defela Ltd | Wholesale & retail | 2025 |
| Defence Submersibles International Limited | Other services | 2021 |
| Defiant Retail Limited | Wholesale & retail | 2004 |
| Delamere Healthcare Ltd | Administrative & support | 2018 |
| Delcreth Ltd | Professional & scientific | 2015 |
| Delcreth Productions Ltd | Information & communication | 2020 |
| Deli-Icious 26 Ltd | Hospitality | 2026 |
| Deliverybyte Ltd | Information & communication | 2024 |
| Delmo Holdings Limited | Professional & scientific | 2008 |
| Delph Tavern Limited | Hospitality | 2002 |
| Delphside Properties Limited | Real estate | 2004 |
| Demcouk Ltd | Wholesale & retail | 2025 |
| Demin Properties Ltd | Real estate | 2024 |
| Demiversum | Professional & scientific | 2023 |
| Dennis Goulding Limited | Construction | 2005 |
| Dental Life Sciences Ltd | Health & social care | 1998 |
| Dentcraft Limited | Wholesale & retail | 1999 |
| Denwar Properties Limited | Real estate | 1952 |
| Deodam Limited | Health & social care | 2026 |
| Derby House Dogs Ltd | Other services | 2025 |
| Derma Reviv Clinic Ltd | Health & social care | 2024 |
| Dermadrop UK Ltd | Wholesale & retail | 2025 |
| Deroma Reach Ltd | Professional & scientific | 2020 |
| Dersk Ltd | Transport & logistics | 2023 |
| Design and Trade Limited | Extraterritorial | 2021 |
| Design Business Interiors Limited | Construction | 1996 |
| Design by Datum Ltd | Professional & scientific | 2020 |
| Design Plumbing Services Limited | Construction | 2016 |
| Designed in Ernest Limited | Professional & scientific | 2024 |
| Designer and Cheap Limited | Wholesale & retail | 2023 |
| Desporti | Professional & scientific | 2023 |
| Dest Projects Limited | Professional & scientific | 2015 |
| Develop 89 Limited | Construction | 2025 |
| Developing Matters CIC | Education | 2016 |
| Development Coaching 4 Players Limited | Arts & recreation | 2020 |
| Development Science Holding Ltd | Professional & scientific | 2024 |
| Devine Smart Solutions Ltd | Wholesale & retail | 2025 |
| Devoid Apparel Limited | Wholesale & retail | 2021 |
| Devoid of Trouble Ltd | Manufacturing | 2025 |
| Dewipe Limited | Manufacturing | 2018 |
| Dexter’S Chicken and Pizza Wigan Ltd | Hospitality | 2025 |
| DF Team Ltd | Administrative & support | 2022 |
| Dgca Services Ltd | Professional & scientific | 2019 |
| DH Detailing Ltd | Wholesale & retail | 2024 |
| DH Plastering (NW) Limited | Construction | 2008 |
| DH13 Trading Ltd | Wholesale & retail | 2023 |
| DHA NW Ltd | Professional & scientific | 2023 |
| Diamond Business Interiors Ltd | Wholesale & retail | 1997 |
| Diamond Community Support Centre CIC | Arts & recreation | 2022 |
| Diamond Digital Ltd | Professional & scientific | 2021 |
| Diamond Homes (NW) Limited | Real estate | 2022 |
| Diamondpeak Group Ltd | Wholesale & retail | 2025 |
| Dibia Properties Limited | Real estate | 2025 |
| Dickinson Murphy & Co Limited | Professional & scientific | 2005 |
| Dickinson Transport Ltd | Transport & logistics | 2021 |
| Diesel Injection Specialist Ltd | Administrative & support | 2017 |
| Diesel Power Solutions Ltd | Administrative & support | 2010 |
| Different Doors Ltd. | Professional & scientific | 2021 |
| Digital BE Ltd | Professional & scientific | 2019 |
| Digital Business Solutions Limited | Information & communication | 1992 |
| Digital Construction Ltd | Construction | 2018 |
| Digital Dental Limited | Health & social care | 2000 |
| Digital Dream Factory Ltd | Information & communication | 2024 |
| Digital Finch Limited | Information & communication | 2015 |
| Digital Impressions Ltd | Professional & scientific | 2016 |
| Digital Workx Ltd | Information & communication | 2022 |
| Digital World Business Academy CIC | Information & communication | 2025 |
| Digitalarc Financial Solutions Ltd | Administrative & support | 2026 |
| Digt Ltd | Information & communication | 2021 |
| Dillon Properties Ltd | Real estate | 2025 |
| Dillon Services Limited | Administrative & support | 2002 |
| Dilly Dallys Deli Ltd | Hospitality | 2025 |
| Dimension H&S Ltd | Professional & scientific | 2022 |
| Dimensional Control for Construction Ltd | Construction | 2025 |
| Dimma Bakes CIC | Manufacturing | 2026 |
| Dinkydot Marketing Ltd | Administrative & support | 2019 |
| Dino Decking Ltd | Wholesale & retail | 2017 |
| Dino Roller Doors Ltd | Construction | 2025 |
| Diocel Ltd | Financial services | 2023 |
| Dipnenjoy Ltd | Hospitality | 2025 |
| Direct Building Service Ltd | Construction | 2012 |
| Direct Network Services Ltd | Professional & scientific | 2016 |
| Direct Opticians Ltd | Health & social care | 2005 |
| Direct Power Solutions Ltd | Manufacturing | 2013 |