| 03710226 Limited | Manufacturing | 1999 |
| 101 Joinery Ltd | Construction | 2023 |
| 12-18 Greenock Mews RTM Company Limited | Households | 2020 |
| 1309 Properties Limited | Real estate | 2022 |
| 1620 Capital Limited | Financial services | 2026 |
| 1821 Property Consultancy Services Limited | Real estate | 2024 |
| 19-24 Greenock Mews RTM Company Limited | Households | 2020 |
| 2 by 2 Pet Supplies Limited | Wholesale & retail | 2012 |
| 2 Spec Redevelopments/Maintenance Ltd. | Construction | 2010 |
| 20POINT9 Ltd | Manufacturing | 2010 |
| 25-30 Greenock Mews RTM Company Limited | Households | 2020 |
| 2ND Chance NW CIC | Arts & recreation | 2026 |
| 2ND Law Limited | Information & communication | 2022 |
| 365 Management Solutions Ltd | Hospitality | 2017 |
| 365 Prop Co Limited | Real estate | 2024 |
| 365 Property Solutions Ltd | Other services | 2022 |
| 365 Solutions Group Limited | Financial services | 2025 |
| 39 Falkner Square Management Company Limited | Real estate | 2003 |
| 3B Controls Ltd | Manufacturing | 2003 |
| 3RD I Solution Ltd | Administrative & support | 2018 |
| 3V3 Academy Ltd | Arts & recreation | 2025 |
| 5 Star Kidz Ltd | Information & communication | 2024 |
| 6-11 Greenock Mews RTM Company Limited | Households | 2020 |
| 66 Noodle Ltd | Hospitality | 2023 |
| 67/73 Farnworth Street Widnes Management Company Limited | Households | 2000 |
| 9 Stones Maintenance Ltd | Households | 2019 |
| 971 Services Limited | Administrative & support | 2018 |
| A & a Signs & Safety Supplies Limited | Manufacturing | 2011 |
| A & D Transport (NW) Limited | Transport & logistics | 2006 |
| A & S Housing Developments Ltd | Real estate | 2026 |
| A B BET Ltd | Arts & recreation | 2005 |
| A Bound Enterprises Ltd | Hospitality | 2018 |
| A E Glen Haulage Limited | Transport & logistics | 2018 |
| A Grape Pairing Ltd | Wholesale & retail | 2024 |
| A J Investments North West Limited | Hospitality | 2002 |
| A Line Stairlifts Limited | Wholesale & retail | 2004 |
| A Rampling Financial Services Limited | Financial services | 2017 |
| A Riley Property Limited | Real estate | 2022 |
| A Space Called Home Ltd | Real estate | 2016 |
| A Turner Consulting Limited | Information & communication | 2022 |
| A&A Bridal Atelier: Ever After Ltd | Wholesale & retail | 2025 |
| A&A Powder Coating North West Ltd | Construction | 2026 |
| A&Ch Logistics Ltd | Transport & logistics | 2015 |
| A&P Roofing of Widnes Ltd | Construction | 2015 |
| A&S Rags Enterprise Ltd | Wholesale & retail | 2021 |
| A. M. Contract Cleaning Limited | Administrative & support | 2013 |
| A.B.M. Engineering Services Limited | Extraterritorial | 2024 |
| A.F.&David Transport Ltd | Transport & logistics | 2023 |
| A.L Valeting Ltd | Administrative & support | 2023 |
| A.R.I Communications Limited | Information & communication | 2018 |
| A2B (Widnes) Ltd | Transport & logistics | 2019 |
| A2B Cable Installations. Ltd | Administrative & support | 2017 |
| Aadhya Enterprises Limited | Health & social care | 2015 |
| Aasa Global Ltd | Wholesale & retail | 2026 |
| AAT Projects Ltd | Professional & scientific | 2012 |
| AB Building & Electrical Ltd | Construction | 2002 |
| Abba Commercials Limited | Wholesale & retail | 2002 |
| Abba Developments Limited | Financial services | 2019 |
| Abbadeboss Business Solutions & Co Ltd | Wholesale & retail | 2023 |
| Abbey Residential Ltd | Information & communication | 2016 |
| Abbi Signs & Designs Limited | Manufacturing | 2009 |
| Abfaqeeri Ltd | Wholesale & retail | 2025 |
| ABG Agencies Limited | Professional & scientific | 2021 |
| ABG Sport Limited | Real estate | 2015 |
| Able Management Widnes Ltd | Hospitality | 2019 |
| ABM Widnes Limited | Extraterritorial | 2010 |
| About Smiles Limited | Health & social care | 2016 |
| AC Fish Limited | Hospitality | 2026 |
| Academy Cheer Ltd | Arts & recreation | 2022 |
| Academy Estate & Letting Agents Limited | Real estate | 2014 |
| Acarel Ltd | Real estate | 2023 |
| Access Community Services Limited | Health & social care | 2002 |
| Access Made Safe Ltd | Professional & scientific | 2010 |
| Access Material Solutions Ltd | Wholesale & retail | 2020 |
| Ace Blinds Limited | Manufacturing | 2022 |
| ACI Accounts Ltd | Professional & scientific | 2024 |
| ACI Electrical Limited | Construction | 2004 |
| ACI Electrical Limited Partnership | | 2026 |
| ACM Bars Ltd | Hospitality | 2025 |
| ACM Logistics Solutions Limited | Transport & logistics | 2019 |
| ACM Projects & Automation Ltd | Professional & scientific | 2023 |
| Acorn Property (NW) Limited | Real estate | 2010 |
| ACT Risk Solutions Limited | Professional & scientific | 2025 |
| Activ Engagement & Education C.I.C. | Education | 2019 |
| Actus Verto Limited | Professional & scientific | 2020 |
| Actus Verto Technologies Limited | Information & communication | 2026 |
| AD Connect Ltd | Information & communication | 2018 |
| AD Recycling Holdings Limited | Financial services | 2022 |
| AD Recycling Limited | Other services | 2018 |
| Ad-On Home Extensions Ltd | Construction | 2025 |
| Adam Benyon Cars Limited | Wholesale & retail | 2025 |
| Adam JOE Roberts Photography Ltd | Professional & scientific | 2023 |
| Adam Lythgoe Holdings Limited | Financial services | 1948 |
| Adam Lythgoe Limited | Financial services | 1963 |
| Adam of London Ltd | Wholesale & retail | 2020 |
| Adam Sutton Estates Limited | Real estate | 2019 |
| Adanna Properties Ltd | Real estate | 2022 |
| Adaptive Build Ltd | Construction | 2025 |
| Adaptive Drywall Solutions Ltd | Other services | 2021 |
| Adaptive Drywall Systems Ltd | Construction | 2019 |