| Quanta Commerce Ltd | Professional & scientific | 2023 |
| Quantum Brickwork Services Limited | Construction | 2014 |
| Quantumtide Limited | Professional & scientific | 2016 |
| Quay Personnel Limited | Administrative & support | 2006 |
| Quayside (Newcastle-Upon-Tyne) Management Company NO.2 Limited | Households | 1997 |
| Queers of the North CIC | Professional & scientific | 2026 |
| Quetta Lawson Ltd | Information & communication | 2023 |
| Quick GEN Limited | Information & communication | 2008 |
| R G Turnbull and Associates Limited | Professional & scientific | 2018 |
| R J Forsyth Ltd | Administrative & support | 2021 |
| R&W G Consulting Limited | Professional & scientific | 2021 |
| R.E.Nails and Beauty Ltd | Other services | 2025 |
| Rahman & Sons (Investment) Company Limited | Households | 1985 |
| Rahman Leisure (W/Bay) Ltd | Hospitality | 2017 |
| Rainbow Bay Limited | Wholesale & retail | 2025 |
| Rakriss Property Services Ltd | Real estate | 2020 |
| RAM Construction Group (North East) Limited | Construction | 2019 |
| RAM Developments (North East) Ltd | Real estate | 2024 |
| Rang Properties Ltd | Real estate | 2024 |
| RAY Prince Financial Planning Limited | Financial services | 2012 |
| RAY Trading Ltd | Wholesale & retail | 2026 |
| RB Inspection Services Ltd | Professional & scientific | 2020 |
| RB Select Ltd | Administrative & support | 2025 |
| RBS Technical Services Limited | Professional & scientific | 2012 |
| Rdnc Installation Limited | Construction | 2007 |
| Real Life Films Ltd | Information & communication | 2007 |
| Real Phase Ltd | Information & communication | 2023 |
| Really Good Printing Limited | Manufacturing | 2025 |
| Red House Investments Limited | Financial services | 2015 |
| Red Oak Residential Ltd | Real estate | 2025 |
| Redgate Lodge Bodyshop Limited | Wholesale & retail | 2020 |
| Redgate Lodge Limited | Wholesale & retail | 2012 |
| Redgate Lodge Service Centre Limited | Extraterritorial | 2021 |
| Redhat Aquisition Limited | Professional & scientific | 2020 |
| Redwolf Services Ltd | Construction | 2022 |
| Regency Apartments RTM Company Limited | Households | 2008 |
| Regular Pattern Limited | Information & communication | 2021 |
| Relish Marketplace Ltd | Wholesale & retail | 2023 |
| Relish Mezeriye Limited | Hospitality | 2013 |
| Remnex Partners Limited | Professional & scientific | 2024 |
| Remote Maintenance Systems Limited | Administrative & support | 2019 |
| Renovat Ltd | Construction | 2017 |
| Resurrection Hairdressing Ltd | Other services | 2022 |
| Retromodern.Co.Uk Limited | Wholesale & retail | 2001 |
| Reuse and Relove CIC | Wholesale & retail | 2025 |
| Reveal Imaging Limited | Professional & scientific | 2010 |
| Revival Hair (NE) Ltd | Other services | 2014 |
| Revoli Ecobuild Ltd | Construction | 2024 |
| RG Loft Conversions Ltd | Construction | 2015 |
| Rhodes Real Estate Ltd | Real estate | 2026 |
| Richard Bown & Co Limited | Professional & scientific | 2007 |
| Richards Installations Ltd | Construction | 2017 |
| Richardsons Sales and Lettings Limited | Real estate | 2011 |
| Ricms Ltd | Other services | 2016 |
| Ridgway & Newton Ltd | Administrative & support | 2015 |
| Ridley Technical Services Limited | Manufacturing | 2003 |
| RIF Restaurant Limited | Hospitality | 2018 |
| RIG West Ltd | Construction | 2021 |
| Riggermiller Ltd | Manufacturing | 2021 |
| Right Mortgage Solutions Limited | Financial services | 2006 |
| Right Time Consultancy Limited | Real estate | 2011 |
| Right Time Security Consultancy Ltd | Administrative & support | 2019 |
| Rigtech Ltd | Construction | 2019 |
| RIR Property Ltd | Real estate | 2024 |
| Rise Learning Group Ltd | Education | 2011 |
| Rjjc Ltd | Hospitality | 2026 |
| RJM Brickwork Ltd | Construction | 2023 |
| RNB Consulting Limited | Construction | 2019 |
| Robava Bathrooms Ltd | Wholesale & retail | 2021 |
| Robbie Tolan Music Ltd | Arts & recreation | 2024 |
| Robert Jobson Engineering Limited | Manufacturing | 2022 |
| Robinsons Waste Removal Ltd | Water & waste | 2023 |
| Robson Packaging Consultants Ltd | Professional & scientific | 2025 |
| Robyte Ltd | Information & communication | 2021 |
| Rockcliffe Bodywork (Whitley Lodge) Limited | Wholesale & retail | 1985 |
| Roker 1960 Limited | Extraterritorial | 2014 |
| Role Services Limited | Wholesale & retail | 2026 |
| Roll Dice Ltd | Wholesale & retail | 2024 |
| Roll Lift Ltd | Other services | 2011 |
| RON Crow & SON Roofing Contractors Ltd | Construction | 2022 |
| Rooby Ltd | Construction | 2021 |
| Ropaint Ltd | Professional & scientific | 2023 |
| Rosabel Ltd | Real estate | 2022 |
| Rough Sea Productions Limited | Information & communication | 2022 |
| Roughead Properties Ltd | Real estate | 2024 |
| Rowland Electrical Limited | Construction | 2026 |
| Rowley Ecom Ltd | Wholesale & retail | 2021 |
| RPN Planning Limited | Professional & scientific | 2023 |
| RSR Hospitality WB Ltd | Hospitality | 2026 |
| RTI Joinery Limited | Construction | 2023 |
| RU Consulting Limited | Information & communication | 2017 |
| RU Listening Ltd | Arts & recreation | 2014 |
| Ruan Properties Ltd | Real estate | 2021 |
| Ruby Residentials NE Ltd | Real estate | 2025 |
| Ruhl and Young Limited | Construction | 2002 |
| Rumney Integrity Consulting Ltd | Professional & scientific | 2014 |
| Rustic CUP Ltd | Hospitality | 2018 |
| Rxpress Limited | Wholesale & retail | 2025 |
| Ryder and Associates Limited | Professional & scientific | 2012 |
| S & J Cunningham Ltd | Construction | 2023 |