| Neuvo Ramsbottom Limited | Hospitality | 2023 |
| New Leaf Topco Limited | Other services | 2017 |
| Nikoo Distribution Limited | Administrative & support | 2007 |
| NJA Joinery Limited | Construction | 2003 |
| Number 1 Fire Protection Ltd | Construction | 2018 |
| NW Constructs Limited | Construction | 2025 |
| Ogard Corporate Investment Company Limited | Financial services | 2021 |
| Ogene Ltd | Wholesale & retail | 2020 |
| Omni Body Limited | Other services | 2019 |
| ON the EBB Limited | Transport & logistics | 2019 |
| Optimal Actuarial Solutions Limited | Financial services | 2011 |
| Oraapps Consultancy Limited | Information & communication | 2011 |
| OS & OS Limited | Administrative & support | 2023 |
| P S Harbach Limited | Information & communication | 2020 |
| P.A.H Joinery and Building Ltd | Construction | 2013 |
| Paine Electrical Limited | Construction | 2003 |
| PAR High Ltd | Hospitality | 2025 |
| Parker Body Repairs Limited | Wholesale & retail | 2003 |
| Pchc Limited | Manufacturing | 1974 |
| Pearson Fraser Limited | Professional & scientific | 2004 |
| Pennine Anaesthetic Company Ltd | Health & social care | 2012 |
| Perfect Parks Limited | Wholesale & retail | 2019 |
| Phoenix Imaging Services Ltd | Health & social care | 2021 |
| Phoenix OD & HR Consulting Ltd | Administrative & support | 2022 |
| Pillar Force Limited | Administrative & support | 1996 |
| Piper Medical Communications Ltd | Information & communication | 2016 |
| Polarvoltine Ltd | Administrative & support | 2018 |
| Popup Bikes Ancoats Limited | Hospitality | 2025 |
| Poxon Construction and Building Limited | Construction | 2022 |
| Precision Tube & Laser Ltd | Manufacturing | 2023 |
| Prestwich Cycle Factors Limited | Wholesale & retail | 2007 |
| Priority HAZ Limited | Water & waste | 2015 |
| Products 4 YOU Limited | Manufacturing | 1997 |
| Propus Ltd | Professional & scientific | 2019 |
| QQ Consultancy Limited | Professional & scientific | 2022 |
| Qualitas Training & Consultancy Limited | Administrative & support | 2004 |
| Quality & Equality Limited | Professional & scientific | 2006 |
| R and R Groundworks Limited | Construction | 2015 |
| Raon Limited | Construction | 2010 |
| RDM Software Consultancy Limited | Information & communication | 1997 |
| Recruit Right Limited | Administrative & support | 2011 |
| Redmond Creative Productions Limited | Arts & recreation | 2026 |
| Reframe Technologies Limited | Information & communication | 2021 |
| Refrigeration Equipment Wholesale Ltd | Wholesale & retail | 2007 |
| Reilloc Chain Limited | Manufacturing | 1977 |
| RGN Flooring Supplies Limited | Wholesale & retail | 2006 |
| Ridge Crest Homes Limited | Real estate | 2016 |
| Riskbasedquality Limited | Information & communication | 2010 |
| Riverside Creatives Ltd | Hospitality | 2017 |
| RJH Stanhope Limited | | 2011 |
| RKB Ventures Ltd | Hospitality | 2013 |
| Robin Hood Travel Limited | Transport & logistics | 1981 |
| Rodney Street 37 Limited | Real estate | 2012 |
| Run When Ready Ltd | Hospitality | 2025 |
| Sandafayre Group Limited | Financial services | 2017 |
| Sanders Machinery Limited | Wholesale & retail | 1983 |
| Sarstan Ltd | Hospitality | 2012 |
| Savs (Whitefield) Ltd | Arts & recreation | 2018 |
| SDL GAS Limited | Construction | 2023 |
| SDM Legal Limited | Professional & scientific | 2018 |
| Sedimentology and Reservoir Development Limited | Administrative & support | 2010 |
| Self Build Services (South West) Limited | Construction | 2006 |
| Sepree Limited | Information & communication | 2013 |
| Service Solutions (FM) Limited | Manufacturing | 2012 |
| Servlite U.K. Limited | Wholesale & retail | 1991 |
| Seven and a Half Ltd | Administrative & support | 2014 |
| SFT (Step Forward Tuition) Ltd | Health & social care | 2023 |
| Sheffield Carers Centre | Health & social care | 1994 |
| Shoemaster Bellevale Ltd | Other services | 2010 |
| Short Theta Ltd | Information & communication | 2011 |
| Skandium London Limited | Information & communication | 2019 |
| Slaters Club Limited | Hospitality | 1990 |
| Smart Robots, Dumb People Ltd | Information & communication | 2015 |
| SMB Capital Ltd | Professional & scientific | 2018 |
| Sndy Limited | Other services | 2019 |
| Sophos Healthcare Consulting Ltd | Health & social care | 2020 |
| South Field Way (Cheltenham) Limited | Wholesale & retail | 2018 |
| South Yorkshire Roof Repairs Ltd | Construction | 2019 |
| Spa Environmental Care Limited | Administrative & support | 1996 |
| Spexy Limited | Health & social care | 2013 |
| SPL Electrical Limited | Construction | 2011 |
| Sprint Management Services Limited | Professional & scientific | 2012 |
| Starling Technologies Ltd | Professional & scientific | 2020 |
| Stavert Zigomala Limited | Financial services | 1923 |
| Stepping Stones Wealth Management Limited | Financial services | 2012 |
| Supper Entertainment Ltd | Hospitality | 2011 |
| Sustainable Wealth Ltd | Financial services | 2017 |
| Swire Properties (Dalton) Ltd. | Real estate | 2010 |
| Tallmarsh Limited | Real estate | 1988 |
| Telford Way (Holdings) Limited | Manufacturing | 2012 |
| THE Associates Building Services Consulting Engineers Limited | Professional & scientific | 2000 |
| THE Beauty Project Cheshire Limited | Other services | 2017 |
| THE Collective Community Trust | Education | 2023 |
| THE Croft (RCH) Limited | Health & social care | 2009 |
| THE Ethicurean Limited | Hospitality | 2021 |
| THE Garden Bar Monton Limited | Hospitality | 2020 |
| THE Law Boutique Limited | Professional & scientific | 2015 |
| THE Site Supply Group Limited | Financial services | 2010 |
| THE Surgeons Chambers Limited | Health & social care | 2017 |
| Third Pear Properties Limited | Real estate | 2020 |