| Peak Business Centre Ltd | Real estate | 2025 |
| Peak Electrical Solutions Ltd | Other services | 2026 |
| Peak Reformer Studio Ltd | Education | 2026 |
| Peakland Laundries Limited | Other services | 2014 |
| Peter J Birch Joinery & Building Ltd | Manufacturing | 2001 |
| Pinfold Shepherds Huts Ltd | Manufacturing | 2022 |
| Power Transmissions International Limited | Wholesale & retail | 2007 |
| Process Engineering Design Online Limited | Professional & scientific | 2002 |
| PT Glossop Limited | Arts & recreation | 2022 |
| Rediscovery Consulting Ltd | Administrative & support | 2020 |
| Richard Payne Builders Ltd | Construction | 2014 |
| Ringbay Ltd | Manufacturing | 2003 |
| ROB Wilson Art Limited | Arts & recreation | 2013 |
| Rotaflow FV Limited | Manufacturing | 1984 |
| Rowlands Farm Limited | Hospitality | 2018 |
| Rubys Whaley Ltd | Hospitality | 2024 |
| S C Motors (High Peak) Ltd | Wholesale & retail | 2026 |
| S Searle Building and Joinery Ltd | Construction | 2025 |
| Safety and Risk Consulting Ltd | Professional & scientific | 2014 |
| Sayle Construction Ltd | Construction | 2019 |
| Shale Valley Properties Ltd | Real estate | 2019 |
| Shallcross Hall Management Company Limited | Households | 2005 |
| Sharp Creative Design Limited | Professional & scientific | 2012 |
| Sheps Arms Ltd | Hospitality | 2022 |
| Sherratt & Co Engineering Services Ltd | Administrative & support | 2020 |
| Sidco Services Ltd | Financial services | 2016 |
| Simon Coupe Heating & Plumbing Services Ltd | Construction | 2018 |
| Sunart Fields Limited | Agriculture & fishing | 2020 |
| T Cooper Properties Ltd | Real estate | 2022 |
| T&T Barbers (High Peak) Ltd | Other services | 2026 |
| THE Bifolddoor and Decking Shop Limited | Wholesale & retail | 2020 |
| THE Clothes Shop (UK) Ltd | Other services | 2016 |
| THE Cyclin BUS Ltd | Arts & recreation | 2017 |
| THE Esthie Academy Ltd | Education | 2026 |
| THE Little Mill Inn Ltd | Hospitality | 2019 |
| THE OWL of Minerva Limited | Arts & recreation | 2017 |
| THE Quarter Sawn Oak Company Limited | Wholesale & retail | 2011 |
| THE Star (HWS) Limited | Hospitality | 2015 |
| THE Waltzing Weasel Limited | Hospitality | 2013 |
| THQ Whaley Bridge Ltd | Other services | 2015 |
| Tilbrook Builders Limited | Construction | 2016 |
| Valley Creative Enterprise Ltd | Other services | 2014 |
| Venus Business Support Limited | Administrative & support | 2008 |
| Vision Retail Group Ltd | Wholesale & retail | 2025 |
| Vistar Network Ltd | Wholesale & retail | 2025 |
| W P Murphy Limited | Construction | 2006 |
| Water North West Ltd | Other services | 2023 |
| Whaley Bridge Automotive Limited | Wholesale & retail | 2022 |
| Whaley Bridge Canal Group CIC | Wholesale & retail | 2019 |
| Whaley Bridge Convenience Store Limited | Wholesale & retail | 2026 |
| Wigs UP North LLP | | 2006 |
| Wooddisse & Co Ltd | Other services | 2020 |
| Woodlings Nursery Limited | Education | 2018 |
| Worldwide Sporting Publications Limited | Administrative & support | 1971 |
| Zelda & Company Limited | Extraterritorial | 2013 |