| Eco Clear Solutions Limited | Construction | 2024 |
| Eco Green Developments Limited | Construction | 2012 |
| ECO4FREE Ltd | Energy | 2025 |
| Ecological Research Ltd | Professional & scientific | 2017 |
| Eden Hair & Beauty Limited | Other services | 2010 |
| Edgson Estates Ltd | Real estate | 2019 |
| Edmond Consultants Ltd | Professional & scientific | 2022 |
| Edwards Hvac Consultants Limited | Other services | 2008 |
| Edwards Welding & Fabrication Limited | Professional & scientific | 2023 |
| EDZ Limited | Wholesale & retail | 2008 |
| Egpt Personal Training Ltd | Arts & recreation | 2023 |
| Eightstavordale Limited | Households | 2015 |
| EIJ Properties Limited | Real estate | 2014 |
| Ejrl Limited | Arts & recreation | 2006 |
| EJS Carpentry Limited | Manufacturing | 2015 |
| Elare Broadmayne Limited | Construction | 2020 |
| Elare Management Ltd | Construction | 2024 |
| Electra Shop Limited | Wholesale & retail | 2009 |
| Electric Bike Racing Ltd | Arts & recreation | 2023 |
| Electronic Measurement Systems Limited | Manufacturing | 1991 |
| Electronics Afloat Limited | Administrative & support | 2000 |
| Elephant Mountain Coffee Company Limited | Extraterritorial | 2011 |
| Elfin Oriel Limited | Health & social care | 2007 |
| Elise Hospitality Ltd | Hospitality | 2023 |
| Elite Consultancy (Dorset) Limited | Professional & scientific | 2012 |
| Elite One Security Ltd | Administrative & support | 2019 |
| Elite Shutters Ltd | Construction | 2025 |
| Elite Tattoo and Piercings Weymouth Limited | Other services | 2015 |
| ELLEV8 Limited | Arts & recreation | 2025 |
| ELLEV8 Serenity Limited | Health & social care | 2025 |
| Elliot and Co LLP | | 2001 |
| Elluna Weymouth Ltd | Health & social care | 2025 |
| Elrich Limited | Professional & scientific | 2006 |
| Elwell Management Limited | Households | 2004 |
| Ember Haus Ltd | Health & social care | 2026 |
| Ember Marine Ltd | Manufacturing | 2023 |
| Emergency Care Solutions Limited | Health & social care | 2013 |
| Emma Beauty Weymouth Limited | Other services | 2024 |
| END2END Property Development Ltd | Construction | 2024 |
| Endodontist Weymouth Limited | Health & social care | 2024 |
| Enhance Technology Limited | Construction | 2020 |
| Enhanced by Laura Jane Ltd | Other services | 2023 |
| Enhancement Properties Ltd | Real estate | 2018 |
| ENM Media Limited | Professional & scientific | 2019 |
| Enntech Mechanical Engineering Limited | Construction | 2016 |
| Enterprise Support Provision Limited | Professional & scientific | 2010 |
| Entry to Vocational Skills and Training Limited | Education | 2016 |
| Envision VA Services Limited | Public administration | 2023 |
| Enzee Brockenhurst Limited | Hospitality | 2016 |
| Enzo Ristorante Limited | Hospitality | 2001 |
| Equity Release and Mortgage Partnership Ltd | Financial services | 2021 |
| Escape Garden Design & Build Dorset Ltd | Administrative & support | 2025 |
| Esopa Ltd | Administrative & support | 2024 |
| Espionage Place RTM Company Ltd | Households | 2021 |
| Esplanade Property Management Limited | Real estate | 2009 |
| Espresso Coffee Ltd | Wholesale & retail | 2021 |
| Essakhel Ltd | Wholesale & retail | 2025 |
| ETR Metal Finishing Limited | Manufacturing | 2010 |
| Eucaliptus 204 Limited | Households | 2008 |
| Eurofasteners Ltd | Wholesale & retail | 2025 |
| European Life Settlement Association | Other services | 1999 |
| Eventlx Ltd | Arts & recreation | 2020 |
| Everetta Processing Ltd | Information & communication | 2026 |
| Evergreen Woodwork Ltd | Manufacturing | 2021 |
| Everthere Ltd | Information & communication | 2002 |
| Everything Flipflop Limited | Wholesale & retail | 2006 |
| Everythingshop Ltd | Wholesale & retail | 2021 |
| Evolvhr Limited | Administrative & support | 2018 |
| Eweleaze Farm Limited | Agriculture & fishing | 2009 |
| EXE EXE EXE Ltd | Hospitality | 2024 |
| Exgb Ltd | Arts & recreation | 2022 |
| Expert Catering Appliance Services Ltd | Manufacturing | 2014 |
| F G Jones Real Estate Limited | Real estate | 2020 |
| F2 Connect Ltd | Wholesale & retail | 2026 |
| FAB Agility (SW) Limited | Other services | 2021 |
| Faber Investments Limited | Real estate | 2013 |
| Fagar Ltd | Wholesale & retail | 2017 |
| Faircross Court Management Limited | Households | 1973 |
| Fairprice (Weymouth) Limited | Real estate | 1999 |
| Fairview Electronics Ltd | Wholesale & retail | 2001 |
| Falcon Shock Absorbers Limited | Agriculture & fishing | 1988 |
| Falk Construction Ltd | Construction | 2011 |
| Farm & Agriculture Ltd | Real estate | 2025 |
| Farm Services South West Limited | Agriculture & fishing | 2017 |
| Farrington Fresh Ltd | Agriculture & fishing | 2009 |
| Farwell Contracting Limited | Construction | 2025 |
| Farwell Enterprises Ltd | Administrative & support | 2003 |
| Faster Sale Ltd | Construction | 2017 |
| Fastnet Europe Limited | Wholesale & retail | 2014 |
| Fastpaq Ltd | Manufacturing | 2007 |
| Fathom and Blues Limited | Arts & recreation | 2015 |
| Faversham Creek Limited | Professional & scientific | 2010 |
| FBC Events Ltd | Arts & recreation | 2018 |
| FCH Hospitality Limited | Hospitality | 2004 |
| Fearless Limited | Transport & logistics | 2006 |
| Fellows Business Solutions Ltd | Professional & scientific | 2023 |
| Fern Square Management Limited | Other services | 2005 |
| Ferrybridge Marine Limited | Other services | 2011 |
| FG Property Maintenance Ltd | Construction | 2025 |
| Fhare Limited | Real estate | 2013 |