| Daneswood Consulting Limited | Professional & scientific | 2024 |
| Daniel Luke Photography Ltd | Professional & scientific | 2024 |
| Daniel Wheldon Limited | Information & communication | 2013 |
| Danmi Limited | Administrative & support | 2024 |
| Danny & Yuki Sapsford LLP | | 2008 |
| Darlington House (Portmore Park) Management Company Limited | Households | 2018 |
| Darren Costello Limited | Construction | 2008 |
| Dash House Group Ltd | Professional & scientific | 2019 |
| Data Chamber Ltd | Information & communication | 2019 |
| Data Consultants Ltd | Information & communication | 2022 |
| Data OWL Business Services Ltd | Professional & scientific | 2025 |
| Dataception Ltd | Information & communication | 2019 |
| Datasci Ltd | Information & communication | 2024 |
| Datenite Ltd | Information & communication | 2018 |
| David Creates Ltd | Professional & scientific | 2012 |
| David Gallagher Management Limited | Administrative & support | 2013 |
| David Hales Interior Design Limited | Other services | 2002 |
| David Jeary Associates Limited | Professional & scientific | 2013 |
| David Luff Productions Limited | Information & communication | 2011 |
| Davidjb Investments | Financial services | 2026 |
| Dawson Administration Limited | Professional & scientific | 2025 |
| DAX Court Residents Association Limited | Households | 1994 |
| Day Aesthetics Ltd | Health & social care | 2021 |
| Day Corporation Ltd | Wholesale & retail | 2021 |
| Daymark App Ltd | Information & communication | 2026 |
| Daymer Bay Capital Limited | Professional & scientific | 2018 |
| Dayslikethese Limited | Extraterritorial | 2002 |
| Deadline Technical Management Limited | Arts & recreation | 2003 |
| Debbie Widdup Ltd | Arts & recreation | 2014 |
| Decarbonise Capital Limited | Professional & scientific | 2024 |
| Decibel Medical Communications Ltd | Professional & scientific | 2025 |
| Decipher Global Consulting Ltd | Professional & scientific | 2024 |
| Decorum Support Limited | Other services | 2012 |
| Dedham Vale LLP | | 2011 |
| Deeez Services Limited | Administrative & support | 2012 |
| Deff Retail Consulting Limited | Professional & scientific | 2015 |
| Dejag Investment Co Ltd | Real estate | 2013 |
| Delaney Goss Limited | Other services | 2002 |
| Delo Property Management Limited | Real estate | 2020 |
| Deltec Citimail Limited | Real estate | 1988 |
| Deme Building Materials Limited | Administrative & support | 2002 |
| Deniz CAN 1 Ltd | Hospitality | 2023 |
| Dentaid Laboratories Limited | Extraterritorial | 2012 |
| Dentsply Russia Limited | Administrative & support | 1996 |
| Dentsply Sirona Repair Centre (UK) Limited | Health & social care | 2020 |
| Dermapure Limited | Professional & scientific | 2005 |
| Design by Appointment Limited | Wholesale & retail | 1990 |
| Designs International Limited | Administrative & support | 2006 |
| Desolstice Limited | Professional & scientific | 2019 |
| Destination 18 Ltd | Administrative & support | 2019 |
| Details DC Services Ltd | Information & communication | 2018 |
| Detector Studio Limited | Information & communication | 2020 |
| Development Advisory Services International Limited | Professional & scientific | 2013 |
| Devenports Expansion Limited | Real estate | 2025 |
| Devenports Group Limited | Financial services | 2022 |
| Devenports Hampton Limited | Real estate | 2021 |
| Devenports Lettings Limited | Real estate | 2022 |
| Devenports Teddington Limited | Real estate | 2024 |
| Devenports Twickenham Limited | Real estate | 2023 |
| Devlo Limited | Professional & scientific | 2021 |
| Dexacon Ltd | Construction | 2025 |
| DGF Health Ltd | Health & social care | 2025 |
| DGI Developments Limited | Construction | 2023 |
| Dglobal Ltd | Wholesale & retail | 2024 |
| DH Bond Civil Engineering Contractors Limited | Administrative & support | 2010 |
| Dhid Property Limited | Other services | 2015 |
| Dhoni Limited | Wholesale & retail | 2007 |
| Diamond Bargain Deals Limited | Wholesale & retail | 2024 |
| Dickie Connell Creative Limited | Professional & scientific | 2018 |
| Digital Security Technology Associates LP | | 2025 |
| Digital Vortechs Limited | Administrative & support | 2008 |
| Dinemingle Ltd | Hospitality | 2024 |
| Dinermojo Ltd. | Hospitality | 2014 |
| Dione Innes Ltd | Real estate | 2023 |
| Direct Electric Solutions Ltd | Administrative & support | 2021 |
| Disco Wheel Limited | Hospitality | 2024 |
| Discount Tyres & Wheels Limited | Wholesale & retail | 2004 |
| Discover London Ltd | Administrative & support | 2020 |
| Discover Weybridge Ltd | Other services | 2025 |
| Dish Catering Limited | Hospitality | 2002 |
| Distant Voice Limited | Information & communication | 2013 |
| Distinct Sports Brands Limited | Manufacturing | 1996 |
| Distinct Wraps Ltd | Wholesale & retail | 2020 |
| Djad Ltd | Professional & scientific | 2013 |
| DK Reynolds Holdings Ltd | Real estate | 2014 |
| DM Timberworks Limited | Construction | 2022 |
| DMA Innovation Ltd | Professional & scientific | 2020 |
| Dmt-Uk Ltd | Other services | 2022 |
| DNC UK Limited | Administrative & support | 1999 |
| DND Mechanical Ltd | Construction | 2018 |
| Dogs Deli Ltd | Wholesale & retail | 2020 |
| Domeshield Limited | Hospitality | 2003 |
| Domestic Maintenance Solutions Limited | Administrative & support | 2022 |
| Domicare Limited | Health & social care | 2018 |
| Domino 4 Limited | Professional & scientific | 1992 |
| Dorchester Road Dental Limited | Health & social care | 2021 |
| Dore Inns Limited | Hospitality | 2003 |
| Dormy Associates Limited | Wholesale & retail | 2023 |
| Dottt Ltd | Professional & scientific | 2018 |
| Double-Edge Solutions Ltd | Information & communication | 2019 |