| Denis Motors Limited | Professional & scientific | 2007 |
| Design Essence Ltd | Professional & scientific | 2024 |
| Design House Development Consultancy Limited | Professional & scientific | 2016 |
| Design Your Hype Ltd | Wholesale & retail | 2024 |
| Desk&Co Ltd | Administrative & support | 2025 |
| Devonshire Designs Limited | Construction | 2004 |
| Devonshire Green (Kent) Ltd | Professional & scientific | 2018 |
| Devonshire Green Ltd | Professional & scientific | 2017 |
| Dgec Ltd | Manufacturing | 2002 |
| DHP London Limited | Administrative & support | 2007 |
| Dick Mortimer Consultancy Limited | Professional & scientific | 2022 |
| Dickson Electrical Limited | Construction | 2006 |
| Dickson Electrical Services Ltd | Construction | 2022 |
| Diggers 4 U Ltd | Administrative & support | 2025 |
| Digital Identification Ltd | Wholesale & retail | 2019 |
| Digital One Online Ltd | Professional & scientific | 2024 |
| Dijitools Limited | Public administration | 2020 |
| Direct Press Marketing Limited | Wholesale & retail | 1998 |
| Directed Path Limited | Health & social care | 2024 |
| Diverse Stone Limited | Construction | 2013 |
| Djdf Entertainments Limited | Hospitality | 2022 |
| DJK Construction Consultants Limited | Professional & scientific | 2020 |
| DJR Properties Ltd | Real estate | 2018 |
| DL Creative Plastering Ltd | Construction | 2021 |
| DM Air Services Ltd | Transport & logistics | 2023 |
| Dm&Son Services Limited | Construction | 2017 |
| DMC Law Ltd | Professional & scientific | 2014 |
| DMG Property Maintenance Ltd | Construction | 2018 |
| DNA Artist Management Ltd | Administrative & support | 2020 |
| Donna Gordon Ltd | Construction | 2021 |
| Doonpark Films Ltd | Administrative & support | 2016 |
| Dovedale Estate Limited | Real estate | 2019 |
| Dovela Ltd | Information & communication | 2018 |
| Downlock Limited | Administrative & support | 2015 |
| Downs & Company (Kent) Limited | Professional & scientific | 2001 |
| DP Diggers Ltd | Construction | 2019 |
| Dragon Films Ltd | Information & communication | 2019 |
| Draper-Enterprises Ltd | Manufacturing | 2025 |
| Draven Consulting Limited | Financial services | 2019 |
| DRD Property Services Ltd | Real estate | 2019 |
| Dreamcell Ltd | Professional & scientific | 2002 |
| Drew Derivatives Limited | Administrative & support | 2008 |
| Drive Smart Learning Ltd | Education | 2025 |
| DRY Electrical Ltd | Manufacturing | 2018 |
| DSJ JET Tech Ltd | Manufacturing | 2026 |
| Dslc Services Limited | Construction | 2012 |
| DTJ Asset Management Limited | Administrative & support | 2013 |
| DTX Solutions Ltd | Construction | 2009 |
| DUE Amici Limited | Hospitality | 2003 |
| Dunrepo Bespoke Limited | Construction | 2017 |
| Dunrepo Developments Limited | Construction | 2017 |
| Dunrepo Limited | Construction | 2014 |
| Dutton-Williams Property Limited | Real estate | 2020 |
| DW Taxis Limited | Administrative & support | 2017 |
| DWS Solutions Limited | Construction | 2012 |
| E Z Design and Construction Ltd | Professional & scientific | 2017 |
| E.F.G.(Flying Services)Limited | Extraterritorial | 1953 |
| E2 Architecture + Interiors Ltd | Professional & scientific | 2011 |
| EAG Aviation Ltd | Manufacturing | 2013 |
| Eagle Autos (South West) Limited | Wholesale & retail | 2016 |
| Earl Property Management Ltd | Real estate | 2014 |
| Earn London Ltd | Real estate | 2021 |
| Earth IO Ltd | Information & communication | 2021 |
| EB Endeavours Ltd | Real estate | 2021 |
| EC Road Safety Limited | Professional & scientific | 2017 |
| Eco-Electricalcallout Ltd | Construction | 2019 |
| Ecoclimate Global Solutions Ltd | Construction | 2025 |
| Ecosy Home (South East) Ltd | Construction | 2014 |
| ECS Home Ltd | Administrative & support | 2023 |
| Eden Street Partners Ltd | Financial services | 2019 |
| EFG Flying School Limited | Extraterritorial | 2012 |
| EG Works Limited | Other services | 2014 |
| Egerton Gardens (Freehold) Limited | Real estate | 2014 |
| Eirn Solutions Limited | Construction | 2015 |
| Eisiam Media Limited | Professional & scientific | 2026 |
| EJW Advisory Limited | Professional & scientific | 2026 |
| Electric Car Experts Limited | Information & communication | 2018 |
| Electric-Bru (London) Ltd | Wholesale & retail | 2025 |
| Electric-Bru Limited | Wholesale & retail | 2024 |
| Electrical & Environmental Contracting Ltd | Construction | 2022 |
| Elektrika Electrical Services Ltd | Construction | 2020 |
| Eleni London Ltd | Wholesale & retail | 2020 |
| Eles Cosmedic Aesthetic Enhancement Limited | Other services | 2019 |
| ELEV8 Hire Ltd | Administrative & support | 2025 |
| Elevateworkplace Ltd | Hospitality | 2026 |
| Elgin Eagles Accounting Limited | Financial services | 2005 |
| Elijah Estates Ltd | Real estate | 2026 |
| Elite Global Construction Limited | Construction | 2020 |
| Elite Golf Management Limited | Wholesale & retail | 2024 |
| Ellamental Events Ltd | Administrative & support | 2025 |
| Ellamental Ltd | Administrative & support | 2025 |
| Elliott & Elliott Property Development Co Ltd | Construction | 2010 |
| ELM Design & Construction Ltd | Professional & scientific | 2025 |
| ELS (Bromley) Limited | Wholesale & retail | 2016 |
| Elysium Fights Ltd | Arts & recreation | 2026 |
| EMA Services (Kent) Ltd | Professional & scientific | 2026 |
| Embassy Concrete Pumping Limited | Construction | 1997 |
| Embassy Property Services Ltd | Real estate | 2021 |
| Emerge Mechanical Services Ltd | Construction | 2023 |
| Emma Cordiner Consulting Limited | Professional & scientific | 2016 |