| Pronetic Ltd | Information & communication | 2005 |
| Proteus Aero Services Limited | Arts & recreation | 1983 |
| PSM Instrumentation Limited | Manufacturing | 1975 |
| Puzzle Press Limited | Arts & recreation | 2004 |
| QMC Instruments Limited | Manufacturing | 1976 |
| Quadrant Systems Limited | Transport & logistics | 1994 |
| Quality Textiles Limited | Professional & scientific | 1999 |
| Quantum Insights Limited | Professional & scientific | 2006 |
| Queen's Court(Haywards Heath)Limited | Households | 1967 |
| Queensway Garage Limited | Wholesale & retail | 1983 |
| R & S Fuller Ltd | Manufacturing | 2003 |
| R J Brown (Plumbing & Heating) Limited | Construction | 2004 |
| R S Property Co Limited | Hospitality | 1989 |
| R S R Technical Services Limited | Construction | 1997 |
| R. H. Phillips & SON Limited | Professional & scientific | 2004 |
| R.C. Construction Limited | Professional & scientific | 1987 |
| R.D. Plant Hire Limited | Administrative & support | 2002 |
| R.G. Scott (Holdings) Limited | Professional & scientific | 1972 |
| R.W.Wilson(Armature Winders)Limited | Manufacturing | 1961 |
| Rachel Kremer Consultancy Ltd | Professional & scientific | 2023 |
| Radiantt Property LLP | | 2025 |
| Rail-Sig Solutions Limited | Professional & scientific | 2006 |
| Rail-Tech Consultants Limited | Professional & scientific | 2006 |
| Rainbow Manufacturing Limited | Manufacturing | 1992 |
| Rainbow Tax and Accounting Ltd | Professional & scientific | 1994 |
| RAJ Katla Infotech Ltd | Information & communication | 2018 |
| Randall & Chisnell Developments Limited | Extraterritorial | 2006 |
| Rang Services Ltd | Administrative & support | 2017 |
| Ravenscourt Gardens Limited | Households | 2007 |
| RBP Associates Ltd | Professional & scientific | 2006 |
| RC Burgess Hill LLP | | 2019 |
| RCH Electrical (Midlands) Limited | Construction | 2006 |
| Real Rewards Limited | Information & communication | 2005 |
| Realmac Software Limited | Information & communication | 2002 |
| Red Parachute Ltd. | Information & communication | 1996 |
| Red Rabbit Software Limited | Information & communication | 1983 |
| Reddin-Clancy Consulting Ltd | Real estate | 2026 |
| Reeds Electrical & Safety Limited | Construction | 2007 |
| Reeth Properties Limited | Real estate | 2005 |
| Regalzone LLP | | 2002 |
| Regnum Estates Limited | Real estate | 2000 |
| Rentokil Terminix Funding PLC | Financial services | 2026 |
| Resten Jones Ltd | Administrative & support | 2007 |
| Retail Shops (Glencora) Limited | Construction | 1964 |
| Rethought Limited | Information & communication | 2008 |
| RH & RW Clutton LLP | | 2003 |
| Rhythm & Blue Inc. Limited. | Wholesale & retail | 1999 |
| Ricardo Consulting Engineers Limited | Extraterritorial | 2006 |
| Ricardo Investments Limited | Professional & scientific | 1988 |
| Ricardo Limited | Professional & scientific | 1927 |
| Richard Hicks (Provincial) Limited | Real estate | 1931 |
| Richmond External Ltd | Construction | 2025 |
| Right Results Limited | Professional & scientific | 1998 |
| Riley Carpentry Ltd | Construction | 2023 |
| Ringdale Instruments Limited | Extraterritorial | 1998 |
| Ringdale UK Limited | Information & communication | 1993 |
| Rivendale House Limited | Households | 2006 |
| Riverrok Limited | Professional & scientific | 2007 |
| Riverside Sheet Metal and Fabrications Limited | Manufacturing | 1991 |
| RKB Property Ltd | Real estate | 2021 |
| Road Radio Limited | Wholesale & retail | 1973 |
| Robert Baker & Company Limited | Professional & scientific | 2006 |
| Robert Deavall Associates Limited | Real estate | 2003 |
| Robert Sadler and Company Limited | Professional & scientific | 1996 |
| Robert Skene Consulting Limited | Administrative & support | 2001 |
| Roche Diagnostics Limited | Professional & scientific | 1956 |
| Rock Solid IT Limited | Information & communication | 2001 |
| Rocks Landscaping (Sussex) Ltd | Administrative & support | 2006 |
| Roger Mein Estate Agents Limited | Professional & scientific | 2003 |
| Rookborough Limited | Extraterritorial | 1997 |
| Rookpoint Limited | Information & communication | 2007 |
| Rooney Air Limited | Transport & logistics | 2007 |
| Roscomac Limited | Manufacturing | 1976 |
| Rose Grey Consulting Ltd | Professional & scientific | 2023 |
| Roundstone Haulage Limited | Information & communication | 1979 |
| Rowe Film Lighting Limited | Administrative & support | 2005 |
| Rugby Road Freehold Limited | Households | 1987 |
| Ryan Champion Limited | Agriculture & fishing | 1993 |
| Ryman Corporation Limited | Professional & scientific | 2006 |
| S & J Head (Properties) Ltd | Real estate | 2003 |
| S & P Comber Limited | Construction | 1979 |
| S a S Services Limited | Wholesale & retail | 2008 |
| S C Wood Limited | Professional & scientific | 2003 |
| S Jones Business Services Limited | Professional & scientific | 2002 |
| S R P Diamond Drilling Ltd | Construction | 2006 |
| S.G. Design Services Limited | Professional & scientific | 1997 |
| S.P.E. Properties Limited | Real estate | 1998 |
| S.P.T. Limited | Administrative & support | 2004 |
| S6 Consulting Ltd | Professional & scientific | 2025 |
| Sadlers (Chichester) Limited | Professional & scientific | 1993 |
| Sadlers Continuation Limited | Professional & scientific | 2002 |
| Sadlers Wine Bar and Restaurant | | 1993 |
| Sage On-Site Solutions Limited | Information & communication | 2003 |
| Sail Shade World Ltd | Manufacturing | 2024 |
| Sanac Limited | Professional & scientific | 2012 |
| Sanbyte Limited | Information & communication | 2005 |
| Sancarma Limited | Information & communication | 1997 |
| Sandra Slaughter Well-Being Coach Ltd | Professional & scientific | 2007 |
| Satellite Television Advisory Centre Limited | | 1988 |
| Saville Jones Architects Limited | Professional & scientific | 2000 |