| Standard Commercial Property Developments Limited | Construction | 1898 |
| Stanford Industrial Concrete Flooring Limited | Construction | 1990 |
| Stanford Special Projects Limited | Professional & scientific | 2003 |
| Stangroom Properties Limited | Professional & scientific | 1988 |
| Stanley Care Home Limited | Health & social care | 2025 |
| Stanley Horne & Sons Limited | Manufacturing | 1944 |
| Star Cars & Coaches Ltd | Transport & logistics | 2000 |
| Stardata Global Ltd | Wholesale & retail | 2024 |
| Starquote Limited | Real estate | 1986 |
| Starry Antigravity Limited | Wholesale & retail | 2023 |
| State of Israel GUO Feng Chemical Industry Group Co., Ltd | Mining & quarrying | 2023 |
| Static Safe Holdings Limited | Financial services | 2025 |
| Stay Sharp Limited | Manufacturing | 1999 |
| Steel Spinnings Limited | Manufacturing | 1951 |
| Steelercruise Limited | Professional & scientific | 2002 |
| Steelmart International Limited | Manufacturing | 1999 |
| Stelon Industrial Equipment Co., Ltd | Extraterritorial | 2022 |
| Stenmar Gauge & Model Co Ltd | Professional & scientific | 2006 |
| Stephen Maguire Limited | Construction | 2006 |
| Stephen Wallis Business Consultant Limited | Administrative & support | 2003 |
| Stephenson Energy Limited | Professional & scientific | 1925 |
| Sternpark Limited | Real estate | 1993 |
| Steven Whittaker Transport Limited | Transport & logistics | 2002 |
| Stevens Machine Tool Co Limited | Wholesale & retail | 1987 |
| Stevron Industrial Services Limited | | 1982 |
| Stewardson Developments Ltd | Real estate | 2002 |
| Sti-And Retion Technology Limited | Manufacturing | 2023 |
| Stirchley Burger Company Limited | Manufacturing | 2003 |
| Stirling Training Limited | Information & communication | 2004 |
| Stonegate EI Tenanted Estate Trading Limited | Hospitality | 2025 |
| Stonegate Entity 1 Limited | Hospitality | 2023 |
| Stonegate Entity 3 Limited | Hospitality | 2023 |
| Stonegate Entity a Limited | Hospitality | 2023 |
| Stonegate Entity B Limited | Hospitality | 2023 |
| Stonegate Entity C Limited | Hospitality | 2023 |
| Stonegate Group Limited | Hospitality | 2025 |
| Stonegate Group Properties Limited | Hospitality | 2025 |
| Stonegate Trading Limited | Hospitality | 2025 |
| Stonegate UK Midco Limited | Hospitality | 2025 |
| Stoneleigh Property Investments Limited | Financial services | 2004 |
| Stoneware Systems Limited | Information & communication | 2006 |
| Storm Windows Limited | Construction | 2000 |
| Stormrage Tech Limited | Manufacturing | 2025 |
| Stour Valley Homes Limited | Construction | 1985 |
| Stourbridge Garden Services Limited | Administrative & support | 2006 |
| Stourbridge Property Preservation Limited | Construction | 1982 |
| Stourflex Limited | Wholesale & retail | 1947 |
| Stourton Accountancy Services Limited | Professional & scientific | 2003 |
| Strategic Care Solutions Limited | Health & social care | 2007 |
| Streetly Tool Hire Limited | Wholesale & retail | 1989 |
| Strike Angling Ltd | Wholesale & retail | 2000 |
| Strike Electrical Distributors Limited | Wholesale & retail | 2001 |
| Strike Properties Limited | Construction | 2006 |
| Strong Uncle Joy Limited | Manufacturing | 2023 |
| Strongdale Engineering Limited | Manufacturing | 1989 |
| Stuart Bruce Limited | Wholesale & retail | 2005 |
| Studio Halle Immobilien Ltd. | Administrative & support | 2005 |
| Styler Building Ltd | Construction | 2003 |
| Stylo (UK) Ltd | Wholesale & retail | 2016 |
| Suki at the Vine Limited | Professional & scientific | 2002 |
| Summerhill Steels Limited | Real estate | 1990 |
| Sun Confidence Ltd | Wholesale & retail | 2023 |
| Sunflowers Day Nursery Limited | Health & social care | 2002 |
| Sunshine Hikull Ltd | Wholesale & retail | 2023 |
| Sunshine Tropical Limited | Administrative & support | 2008 |
| Suoli Technology Co., Ltd | Professional & scientific | 2013 |
| Supa Specs Express Limited | Health & social care | 2005 |
| Supean Ltd | Transport & logistics | 2020 |
| Sureway Maintenance Limited | Construction | 2005 |
| Surface Technology Products Limited | Wholesale & retail | 1971 |
| Susan J James Consulting Limited | Professional & scientific | 2006 |
| Sustainable Property Developments Limited | Construction | 2002 |
| Sutton Coldfield Cleaning and Maintenance Limited | Administrative & support | 1968 |
| Sutton Coldfield Cricket and Hockey Club Limited | Arts & recreation | 1974 |
| Sutton Coldfield Masonic Hall Company Limited | Real estate | 1903 |
| Sutton Computing Limited | Information & communication | 1979 |
| Sutton Dolphins Limited | Arts & recreation | 2004 |
| SV Application Services Ltd | Administrative & support | 2026 |
| SVP Limited | Real estate | 2001 |
| Swale 4 X 4 Sales Limited | | 2005 |
| Swan Industrial Drives Ltd | Professional & scientific | 1984 |
| Swift Psychology Services Ltd | Health & social care | 2021 |
| Swimrite Wollescote Limited | Arts & recreation | 1996 |
| Syedain & Co Limited | Professional & scientific | 2005 |
| Syren Strategy Limited | Professional & scientific | 2005 |
| System Consultants Limited | Information & communication | 2000 |
| T Cafo ( Leisure ) Limited | Extraterritorial | 2008 |
| T Carroll Builders Limited | Construction | 2003 |
| T D & S Limited | Construction | 1977 |
| T J Homes Limited | Wholesale & retail | 2002 |
| T-S-Dienstleistungen Limited | Administrative & support | 2004 |
| T-Tech Tooling Limited | Manufacturing | 1999 |
| T. J. Wardle Limited | Manufacturing | 2003 |
| T.& T.(Dudley)Tools and Engineering Limited | Manufacturing | 1963 |
| T.Baker & Sons(Transport)Limited | Transport & logistics | 1952 |
| T.K. Enterprises Limited | Hospitality | 1996 |
| T.Morley & Co. Limited | Extraterritorial | 2000 |
| Taji Veeni Limited | Wholesale & retail | 2021 |
| Tallon International Limited | Wholesale & retail | 1973 |
| Tallon Pens Limited | Professional & scientific | 1976 |