| Southfields Building Limited | Construction | 2016 |
| Southway Plumbing and Heating Limited | Construction | 2014 |
| Sovereign Close Residents Company Limited | Households | 1996 |
| Sovereign Stone (Kent) Limited | Manufacturing | 2006 |
| Space Invaders Loft Conversions Limited | Construction | 2014 |
| Spacez Property Group Ltd | Administrative & support | 2015 |
| Spadework Limited | Wholesale & retail | 1984 |
| Spadework Social Enterprises CIC | Wholesale & retail | 2020 |
| Spambrella Ltd | Administrative & support | 2013 |
| SPC Fire Protective Coatings Ltd | Construction | 2025 |
| SPC Kent Limited | Construction | 2017 |
| Spiers Property Management Limited | Real estate | 2022 |
| Spoonn Ltd | Wholesale & retail | 2025 |
| Spring Leaf Aesthetics Ltd | Health & social care | 2022 |
| Springwood Court (Freehold) Limited | Households | 2006 |
| Spritestore Limited | Construction | 1997 |
| Spsg (Holdings) Ltd | Other services | 2017 |
| Spsg Business Solutions Ltd | Professional & scientific | 2011 |
| Spsg Care Holdings Ltd | Financial services | 2026 |
| Spsg Lifestyles Ltd | Arts & recreation | 2019 |
| Spsg Properties Ltd | Real estate | 2014 |
| Squared Lemons Ltd | Information & communication | 2025 |
| SR Creative Curriculum Consultancy Limited | Education | 2025 |
| SSC Real Estate Limited | Real estate | 2019 |
| ST Andrew Properties Ltd | Real estate | 2020 |
| ST Andrews Park (West Malling) NO. 1 Management Limited | Households | 1998 |
| ST Andrews Park (West Malling) NO. 2 Management Limited | Households | 1999 |
| ST Augustine's College of Theology | Other services | 1983 |
| ST Benedict's Centre | Hospitality | 2016 |
| ST George’S Meadow Management Company Limited | Households | 2024 |
| ST Joseph's Playgroup Limited | Education | 2007 |
| ST Nicholas Place Residents Management Company Limited | Households | 2025 |
| ST Paul's Sinfonia | Arts & recreation | 2010 |
| Stable Land and Property Ltd | Real estate | 2024 |
| Stable System Solutions Limited | Information & communication | 1998 |
| Standen Events Limited | Hospitality | 2025 |
| Standen Kitchen Limited | Hospitality | 2026 |
| Star Hill Developments Limited | Real estate | 2021 |
| Starlights Ltd | Construction | 2008 |
| Starma Consulting Ltd | Professional & scientific | 2016 |
| Station Bridge Ltd | Real estate | 2018 |
| Steadman Engineering Services Limited | Administrative & support | 2014 |
| Stealth Training and Consultancy Ltd | Administrative & support | 2019 |
| Stella Communications Ltd | Professional & scientific | 2021 |
| Stephanie Chloe Bila Limited | Professional & scientific | 2016 |
| Stephen Keast Wealth Management Limited | Financial services | 2004 |
| Stepping Stones Resettlement Unit Limited | Health & social care | 1996 |
| Sterry Roofing Services Limited | Construction | 2018 |
| Stones Holdings Limited | Health & social care | 1999 |
| STORE89 Ltd | Wholesale & retail | 2023 |
| Storm Auto Locks Ltd | Other services | 2025 |
| Strater Property UK Limited | Real estate | 2016 |
| Striped Gecko Limited | Real estate | 2018 |
| Strum & Bass Ltd | Wholesale & retail | 2015 |
| Studious Limited | Administrative & support | 2009 |
| Styled Builds LLP | | 2014 |
| Sumit Accountants Ltd | Professional & scientific | 2026 |
| Summerhill (Polegate) Residents Management Company Limited | Households | 2024 |
| Summerville Meadows Management Co. Limited | Households | 2025 |
| Sunnyside Domicilary Support Services Limited | Health & social care | 2010 |
| Sunnyside Domiciliary Holdings Limited | Financial services | 2025 |
| Surrey & Kent Commercial Services LLP | | 2021 |
| Surrey Building Solutions Ltd | Construction | 2021 |
| Sustaintech Africa Ltd | Professional & scientific | 2013 |
| Swan Invest Ltd | Professional & scientific | 2023 |
| Sweet Bee's Support Services Limited | Real estate | 2024 |
| Swift Exterior Cleaning Ltd | Administrative & support | 2026 |
| Swiftreg Ltd | Wholesale & retail | 2020 |
| Swindon & Kent Commercial Services LLP | | 2026 |
| Swiss Link Limited | Professional & scientific | 2008 |
| SWS Fisheries Ltd | Agriculture & fishing | 2021 |
| Sycamore Resources Limited | Administrative & support | 2009 |
| Synchronist Limited | Professional & scientific | 2017 |
| Syndimoz LLP | | 2015 |
| Synergia Partners Ltd | Administrative & support | 2025 |
| SZS Roofing Contractors Ltd | Construction | 2021 |
| T.A.G Managed Services Ltd | Construction | 2018 |
| T.J's Automotive Ltd | Wholesale & retail | 2024 |
| T.T.E. Litho Sales Limited | Manufacturing | 1994 |
| T2 Capital Solutions Ltd | Information & communication | 2024 |
| Taboic Ltd | Construction | 2025 |
| Talking Spirit Limited | Health & social care | 2024 |
| Tallow Commercial Properties Limited | Real estate | 2024 |
| TAM Engineering (Kent) Ltd | Administrative & support | 2017 |
| Tammyj Healthcare Services Limited | Health & social care | 2022 |
| Tamoka Services Ltd | Administrative & support | 2024 |
| Tanner SE1 Holdings Limited | Financial services | 2016 |
| Task Solutions Limited | Professional & scientific | 2004 |
| Tattenhoe Park Phase 7 Residents Management Company Limited | Households | 2025 |
| Taurus Communications Limited | Information & communication | 2014 |
| Taxref Group Ltd | Professional & scientific | 2015 |
| Taylor Brooker - Accountancy Ltd | Professional & scientific | 2010 |
| TB Labs Limited | Information & communication | 2020 |
| TBC Services (London and South East) Ltd | Professional & scientific | 2012 |
| TDM Funeral Services Ltd | Other services | 2024 |
| Teal Nutrition Limited | Health & social care | 2017 |
| Teams Coaching Ltd | Professional & scientific | 2023 |
| Technologyworks (UK) Limited | Arts & recreation | 2005 |
| Techsafe Solutions Limited | Professional & scientific | 2023 |
| Techsflow Ltd | Wholesale & retail | 2020 |