| Reef Financial Consulting Ltd | Financial services | 2015 |
| Reflect Health Partners Limited | Health & social care | 2024 |
| Regal Personnel Limited | Information & communication | 2008 |
| Reinspire Holistic Health and Wellbeing Ltd | Health & social care | 2025 |
| Rejuvenate Skin and Laser Clinic Ltd | Other services | 2024 |
| Relativeto Limited | Health & social care | 2012 |
| Renew Clinic Ltd | Extraterritorial | 2023 |
| Rental Road Ltd | Real estate | 2026 |
| Replay AV & Production Ltd | Arts & recreation | 2016 |
| Resolve Professional Security Services Limited | Administrative & support | 2014 |
| Revive Clinical Services Ltd | Health & social care | 2024 |
| Rfic Consulting Ltd | Professional & scientific | 2026 |
| Rgcm (Holdings) Limited | Construction | 1990 |
| Rgcm Doncaster Limited | Construction | 2024 |
| Rgcm KH Limited | Construction | 2024 |
| Rgcm Limited | Construction | 1990 |
| Rgre Limited | Construction | 2023 |
| RH Fire Safety Ltd | Public administration | 2019 |
| Rhci Limited | Professional & scientific | 2019 |
| Rhgh Services Ltd. | Professional & scientific | 2022 |
| Rich Levy Software Ltd | Information & communication | 2024 |
| Richly Green Property Ltd | Real estate | 2025 |
| Richly Red Estates Ltd | Real estate | 2024 |
| Richly Red Property Ltd | Real estate | 2024 |
| RIK Transport Limited | Transport & logistics | 2023 |
| Ringlestone Consultancy Limited | Administrative & support | 2013 |
| Ritual Art Tattoo Limited | Other services | 2006 |
| River Gateway Residents Management Company Limited | Households | 2025 |
| Riverview Leisure Limited | Administrative & support | 2022 |
| RJ Latimer Limited | Financial services | 2019 |
| Rjkemp Consulting Ltd | Professional & scientific | 2025 |
| RJT Consultancy Services (SE) Limited | Construction | 2014 |
| Rlbarnesgroup Ltd | Construction | 2026 |
| RMC Contracts Kent Ltd | Manufacturing | 2025 |
| RMC Contracts Southeast Ltd | Construction | 2021 |
| RMS (Southern) Ltd | Professional & scientific | 2013 |
| Rob's Cleaning Services. Ltd | Administrative & support | 2025 |
| Robert MAE Limited | Real estate | 2018 |
| Robur MEP Ltd | Construction | 2025 |
| Rochester Distribution Limited | Professional & scientific | 2015 |
| Rochester Health Club Limited | Arts & recreation | 2003 |
| Rochester Kidzone Ltd | Arts & recreation | 2007 |
| Rochester Training and Leisure Limited | Arts & recreation | 2015 |
| Rock Elevator Solutions Ltd | Professional & scientific | 2023 |
| Rocket Sense Limited | Professional & scientific | 2019 |
| Rockspider Offroad Ltd | Wholesale & retail | 2023 |
| Rolin Services Limited | Administrative & support | 2013 |
| Romford Ice Hockey Operations Limited | Arts & recreation | 1993 |
| RON Travel Ltd | Administrative & support | 2020 |
| Ronin Concepts Elite Limited | Administrative & support | 2011 |
| Ronin Concepts Security Solutions Limited | Administrative & support | 2015 |
| Roofgo Ltd | Construction | 2022 |
| Rooster Inns Ltd | Hospitality | 2019 |
| Rose Family Properties Limited | Real estate | 2017 |
| Rose Media Labs Ltd | Professional & scientific | 2024 |
| Roseaceae Consulting Ltd | Professional & scientific | 2023 |
| Rosebery Holdings Ltd | Financial services | 2018 |
| Rosemullion Homes Limited | Construction | 1994 |
| Roth Creative LLP | | 2013 |
| Rowan Gate (Leybourne) Management Company Limited | Households | 2012 |
| Roxproperty Investments Limited | Real estate | 2018 |
| RP Steelworks Ltd | Construction | 2024 |
| RT Gardenscapes Ltd | Administrative & support | 2024 |
| RU Kickz Ltd | Wholesale & retail | 2024 |
| Ruff CUT Productions Ltd | Extraterritorial | 2025 |
| Rugeley (Power Station) Phase 1 Residents Management Company Limited | Households | 2026 |
| Rumar Ltd | Professional & scientific | 2017 |
| Rusthall Veterinary Practice Limited | Professional & scientific | 2009 |
| Ryan LEE Ltd | Real estate | 2026 |
| Ryarsh Lane House Management Company Limited | Households | 1970 |
| S & N Care Ltd | Administrative & support | 2022 |
| S & S Fencing Solutions Ltd | Construction | 2019 |
| S & V Energy Rated Windows Ltd | Professional & scientific | 2022 |
| S Cunningh Core Ltd | Wholesale & retail | 2025 |
| S Kothari | Health & social care | 2020 |
| S Montalto Ltd | Health & social care | 2019 |
| S&L Mechanical Limited | Construction | 2019 |
| S. Yendell Limited | Construction | 2005 |
| S.C.K. Property Limited | Real estate | 2006 |
| S3 Risk Consulting Ltd. | Professional & scientific | 2016 |
| Saas Commercial Limited | Information & communication | 2024 |
| Sadat HCW Ltd | Other services | 2014 |
| Saffer Lifts Limited | Construction | 2017 |
| Saffron Gate (Hove) Limited | Households | 2001 |
| Saga Digital UK Limited | Manufacturing | 2017 |
| Salient Health Limited | Health & social care | 2025 |
| Salmon Carpentry Ltd | Construction | 2021 |
| SAM Healthcare Services Limited | Health & social care | 2019 |
| SAM White Analytics Limited | Professional & scientific | 2021 |
| Samantha Bowles Ltd | Professional & scientific | 2023 |
| Samantha Jane Temple Limited | Extraterritorial | 2021 |
| Same Day GP Limited | Health & social care | 2023 |
| Samrai Management Limited | Professional & scientific | 2015 |
| Sandy Ridge Capital Ltd | Financial services | 2025 |
| Sandymoor JV LLP | | 2018 |
| Sankofa Collective Ltd | Professional & scientific | 2023 |
| Saplings Rural Day Nursery and Preschool Ltd | Health & social care | 2020 |
| Sapphire Partitioning Ltd | Construction | 2016 |
| Sapsford House Freehold Company Limited | Households | 2019 |
| Saptadri Limited | Financial services | 2025 |