| Elserag Ltd | Transport & logistics | 2022 |
| Eltash Ltd | Wholesale & retail | 2025 |
| Elusive Productz Ltd | Wholesale & retail | 2015 |
| ELY Construction Ltd | Construction | 2019 |
| Elyra London Ltd | Wholesale & retail | 2026 |
| Em-Plus Ltd | Administrative & support | 2019 |
| Emaari Jewellers Ltd | Wholesale & retail | 2026 |
| Eman's Food Ltd | Hospitality | 2025 |
| EMC Referrals Ltd | Health & social care | 2019 |
| Emerald Abode Ltd | Real estate | 2022 |
| Emerald Hill Estates Ltd | Other services | 2022 |
| Emerald Keys Ltd | Real estate | 2007 |
| Emeraldo Contract Cleaning Services Limited | Administrative & support | 2002 |
| Emerge Homes Limited | Real estate | 2018 |
| Emergency Heating & Plumbing Ltd | Construction | 2018 |
| Emerging Market Financial Training Ltd | Professional & scientific | 2017 |
| EMF Live Events Limited | Extraterritorial | 2006 |
| EMF Technology Limited | Professional & scientific | 2001 |
| Emilia Igconsult Ltd | Professional & scientific | 2025 |
| Emilia M Ltd | Construction | 2014 |
| Emkay Capital Ltd | Real estate | 2022 |
| Emkay Traders Ltd | Wholesale & retail | 2011 |
| Emmar Traders Ltd | Wholesale & retail | 2019 |
| Emmer Green (2024) Ltd | Wholesale & retail | 2024 |
| Emms Logistics Ltd | Transport & logistics | 2021 |
| Empire Accountants Ltd | Professional & scientific | 2023 |
| Empire Chicken Ltd | Hospitality | 2025 |
| Empire Garages Ltd | Wholesale & retail | 2021 |
| Empire Properties London Ltd | Real estate | 2020 |
| Empire Roofing Services Limited | Construction | 2011 |
| Emport Limited | Wholesale & retail | 2024 |
| Empower Community Care Limited | Information & communication | 2013 |
| Empower Internationale | Health & social care | 2013 |
| Empyrean VC Limited | Real estate | 2025 |
| EMR Safety Solution Ltd | Construction | 2026 |
| EMR Silverthorn Holdings Limited | Wholesale & retail | 2017 |
| EMR Silverthorn Limited | Wholesale & retail | 1978 |
| Emswathty Ltd | Real estate | 2017 |
| Emswathty Properties Ltd | Real estate | 2024 |
| Emswathty Realty Ltd | Real estate | 2024 |
| Emsworth Service Station Limited | Wholesale & retail | 2010 |
| EN Bank Limited | Financial services | 2006 |
| EN Property London Limited | Real estate | 2019 |
| EN Puthu Idea Limited | Wholesale & retail | 2003 |
| Enamel Rooms Corby Ltd | Health & social care | 2025 |
| Enamel Structures Ltd | Real estate | 2013 |
| Enara Ltd | Wholesale & retail | 2025 |
| Enchanted Soul Limited | Wholesale & retail | 2022 |
| Enclave Property Ltd | Real estate | 2025 |
| END2END Development Ltd | Professional & scientific | 2021 |
| Endo & Beyond Ltd | Public administration | 2025 |
| Endoprime Limited | Administrative & support | 2021 |
| Endoscopy & Surgical Associates Limited | Health & social care | 2015 |
| Eneegmaa Events Ltd | Hospitality | 2024 |
| Energy Power Ltd | Other services | 2018 |
| Energy Products UK Ltd | Wholesale & retail | 2021 |
| Energy Technologies International | | 1992 |
| Energysoftserv UK Ltd | Extraterritorial | 2019 |
| Enext (UK) Limited | Wholesale & retail | 2006 |
| Enext Investments Limited | Real estate | 2017 |
| Engineered Green Technologies Limited | Professional & scientific | 2006 |
| Engineering Center (U.K.) Limited | Water & waste | 1985 |
| Engineering Research and Development Limited | Professional & scientific | 2013 |
| English Genie Limited | Extraterritorial | 2011 |
| Enigmartins Limited | Information & communication | 2012 |
| Enjoyy Ltd | Wholesale & retail | 2023 |
| Enkash Consultancy Limited | Financial services | 2015 |
| Enki IP Limited | Administrative & support | 2023 |
| Ennis Group Ltd | Construction | 2017 |
| Entrio Limited | Other services | 2022 |
| Enviro Carpets Limited | Wholesale & retail | 2024 |
| Enviro International Ltd | Wholesale & retail | 2025 |
| Environment YOU Ltd | Administrative & support | 2026 |
| Envision Design and Construction Ltd | Construction | 2023 |
| Envy Enterprise Ltd | Wholesale & retail | 2024 |
| EO Maidenhead Ltd | Construction | 2026 |
| EP Fashion Consulting Ltd | Professional & scientific | 2014 |
| EP2 Packaging Ltd | Administrative & support | 2024 |
| Epbs (UK) Ltd | Other services | 2014 |
| EPC Nationwide Limited | Professional & scientific | 2014 |
| Epex Ltd | Wholesale & retail | 2022 |
| EPH Trading Limited | Manufacturing | 2014 |
| Epione Trading Ltd | Wholesale & retail | 2026 |
| Epoch RJK Limited | Real estate | 2001 |
| EPP Assets Limited | Households | 2025 |
| EPR Assist Ltd | Information & communication | 2026 |
| Equality Lettings Residential Limited | Real estate | 2026 |
| Equator INT Limited | Wholesale & retail | 2008 |
| Equestrian Business Specialist Limited | Administrative & support | 2024 |
| Equinox Power (UK) Ltd | Professional & scientific | 1999 |
| Equity & Capital Ventures Limited | Financial services | 2015 |
| ERA Finances Real Estate Investments Ltd | Financial services | 2022 |
| ERA Road Solutions Ltd | Transport & logistics | 2026 |
| Ericeira Ltd | Administrative & support | 2016 |
| Eridu Logistic Services Ltd | Transport & logistics | 2026 |
| Erindale Limited | Real estate | 2008 |
| Erindale SC Limited | Real estate | 2014 |
| ERM Building & Construction Ltd | Construction | 2024 |
| Ernest&Ernest Ltd | Manufacturing | 2023 |
| Erol Balling Ltd | Construction | 2025 |