| Datashire Limited | Information & communication | 2007 |
| Date the Cloud Ltd. | Wholesale & retail | 2025 |
| Datscom Ltd | Information & communication | 2024 |
| Dattaguru Ltd | Information & communication | 2023 |
| Dauphine Court Management Company Limited | Households | 2023 |
| Dave Consultancy Limited | Financial services | 2024 |
| Daventry Properties Ltd | Real estate | 2025 |
| David Capita Limited | Administrative & support | 2016 |
| David Correy Anderson Limited | Extraterritorial | 2025 |
| David Grimes Audio Ltd | Arts & recreation | 2020 |
| Davinah Limited | Wholesale & retail | 2026 |
| Dawn Glazing Ltd | Manufacturing | 2024 |
| Dawn IT Services Limited | Information & communication | 2009 |
| Dawn Jarvis Ltd | Wholesale & retail | 2019 |
| Dawood International Ltd | Wholesale & retail | 2023 |
| Day One Express Retail Ltd | Wholesale & retail | 2020 |
| Day SON Flooring Ltd | Construction | 2023 |
| Daya Limited | Wholesale & retail | 1983 |
| Days & Years Ltd | Wholesale & retail | 2025 |
| Daytime Ltd | Transport & logistics | 2024 |
| DAZ G.C Services Limited | Administrative & support | 2016 |
| DB Focus Limited | Information & communication | 2014 |
| DB Innovations Ltd | Professional & scientific | 2025 |
| DBT in Mind Limited | Health & social care | 2017 |
| DC & Son’S Electrical Ltd | Construction | 2025 |
| DC Mart Ltd | Real estate | 2024 |
| DC Parcel Ltd | Transport & logistics | 2025 |
| DC Skills Ltd | Professional & scientific | 2019 |
| DD Enterprise Ltd | Administrative & support | 2017 |
| DDM Telecom Ltd | Construction | 2025 |
| DE Fine Investment Properties Ltd | Real estate | 2022 |
| DE Fine Works Ltd | Construction | 2022 |
| DE Israel Allied Business Center & Immigration Services Limited | Public administration | 2016 |
| DEA Arts Limited | Construction | 2017 |
| DEA Consultancy Limited | Professional & scientific | 2023 |
| Deac Constuction Services Ltd | Construction | 2018 |
| Deafinitely Theatre | Arts & recreation | 2005 |
| Deaflondon | Professional & scientific | 2014 |
| Dealforge Group Ltd | Administrative & support | 2024 |
| Dealpride Limited | Administrative & support | 2007 |
| Dealswarehouse Ltd | Wholesale & retail | 2019 |
| Deansbrook Dental Limited | Health & social care | 2025 |
| Dean’S Media Operations Ltd | Information & communication | 2025 |
| Debora Braz Aesthetic & Clinic Ltd | Other services | 2025 |
| Decent Cleaners Ltd | Administrative & support | 2025 |
| Decisive Technology Ltd | Administrative & support | 2014 |
| Decorma Ltd | Construction | 2025 |
| Deed Track Limited | Information & communication | 2016 |
| Deep Ambition Limited | Wholesale & retail | 2021 |
| Deep Clean Experts Ltd | Administrative & support | 2022 |
| Deep Clean Masters Limited | Administrative & support | 2023 |
| Deep Estate Ltd | Real estate | 2024 |
| Deep Ocean Optical Glasses Co., Ltd | Wholesale & retail | 2023 |
| Deepshine Cleaning Ltd | Administrative & support | 2025 |
| Deepu (UK) Limited | Information & communication | 2012 |
| Deevao Limited | Information & communication | 2022 |
| Deeya Logistics Limited | Transport & logistics | 2018 |
| Dee’S Management Services Ltd | Real estate | 2019 |
| Default Media Group Ltd | Information & communication | 2016 |
| Definitejobs Group Ltd | Information & communication | 2023 |
| Degadon Ltd | Construction | 2025 |
| DEI Gratia Investments Ltd | Real estate | 2019 |
| Delight Wedlinka Ltd | Other services | 2013 |
| Delightfully Fresh Limited | Wholesale & retail | 2024 |
| Delilyum Ltd. | Administrative & support | 2024 |
| Deliver on Time Ltd | Other services | 2018 |
| Delta Car Service Centre Limited | Other services | 2019 |
| Delta Estates Holdings Limited | Real estate | 2008 |
| Delta Estates Limited | Construction | 1997 |
| Delta Motors Design Limited | Real estate | 2017 |
| Delta Properties London Limited | Administrative & support | 2009 |
| Delta X London Ltd | Information & communication | 2024 |
| Deltra Electronics Limited | Wholesale & retail | 1988 |
| Deluxe Beauty Ltd | Other services | 2017 |
| Deluxe Laser Aesthetics Limited | Health & social care | 2025 |
| DEM2021 Limited | Construction | 2021 |
| Demah Limited | Administrative & support | 2007 |
| Demeter Realty Ltd | Real estate | 2016 |
| Demi Living Limited | Health & social care | 2025 |
| Demver Shoes & Leather Distribution Company | | 1994 |
| DEN Properties Services Ltd | Real estate | 2015 |
| DEN Rail Limited | Construction | 2016 |
| Dena Investments Ltd | Real estate | 2025 |
| Denishors Maintenance Ltd | Construction | 2020 |
| Dennis Motors Limited | Real estate | 1998 |
| Dental Manufacturing Centre Ltd | Manufacturing | 2007 |
| Dental Training Academy Limited | Education | 2021 |
| Dental Training Consultants Ltd | Education | 2014 |
| Deoner Limited | Wholesale & retail | 2024 |
| Derewals (Holdings) UK Limited | Professional & scientific | 2004 |
| Desai Ventures Ltd | Hospitality | 2021 |
| Desi Label Gang Ltd | Administrative & support | 2026 |
| Design & Beauty Ltd | Other services | 2013 |
| Design and Tech Hub Limited | Professional & scientific | 2020 |
| Design Arena Limited | Information & communication | 2015 |
| Design for Print Limited | Information & communication | 2006 |
| Design Layout & Build Limited | Construction | 2015 |
| Design Metrics Ltd | Wholesale & retail | 2023 |
| Design Transform Hub Ltd | Wholesale & retail | 2025 |
| Designer Consultants Ltd | Professional & scientific | 2023 |