| Demi's Diner Ltd | Hospitality | 2021 |
| Denbigh Removal Service Limited | Transport & logistics | 2025 |
| Denways Ltd | Administrative & support | 2019 |
| Deola Good Property Ltd | Real estate | 2024 |
| Devil's Detail Tattoo and Piercing Club Ltd | Other services | 2024 |
| Devlin Home Improvements Ltd | Construction | 2025 |
| DG Flat Maintenance Ltd | Construction | 2026 |
| DGN 1469 Ltd | Wholesale & retail | 2024 |
| DH3D Designs Ltd | Manufacturing | 2025 |
| Dhanoa Logistics Limited | Transport & logistics | 2026 |
| Dhillon Roofing Ltd. | Construction | 2019 |
| Dhots Ltd | Transport & logistics | 2019 |
| DHS Holdings Limited | Professional & scientific | 2004 |
| Diamond Bright Cleaning Services Limited | Administrative & support | 2020 |
| Diamond Industrial Cleaning Services Ltd | Administrative & support | 2025 |
| Diamond Plumbing & Drainage Ltd | Construction | 2023 |
| Diamond Rubber Company Limited | Manufacturing | 2000 |
| Digimarket Solutions Ltd | Wholesale & retail | 2025 |
| Digital Blue Solutions Limited | Information & communication | 2024 |
| Dilargo Ltd | Information & communication | 2026 |
| Dindle Ltd | Hospitality | 2025 |
| Direct Auto Sales Limited | Wholesale & retail | 2025 |
| Direct Dealz 4 U Limited | Wholesale & retail | 2023 |
| Directtoyou Limited | Wholesale & retail | 2022 |
| Diverse Minds Community C.I.C. | Health & social care | 2026 |
| DJB Pool Hall Limited | Arts & recreation | 2024 |
| DJH Industrial Roofing Services Ltd | Construction | 2013 |
| Djol Balon Investment Limited | Real estate | 2023 |
| DJS Facilities Ltd | Construction | 2022 |
| Djwood Solutions Limited | Professional & scientific | 2022 |
| DKB Carpentry Ltd | Manufacturing | 2023 |
| DKB Essentials Ltd | Wholesale & retail | 2014 |
| DL Capital Finance Ltd | Financial services | 2025 |
| DMA Midlands Ltd | Manufacturing | 2025 |
| DMB Decorators Ltd | Construction | 2026 |
| DNA Floors Limited | Construction | 2026 |
| DNP Plumbing & Heating Ltd | Construction | 2021 |
| Dobdosh Services Ltd | Administrative & support | 2019 |
| DOM' Cash Converters Ltd | Wholesale & retail | 2025 |
| Domestic Commercial & Industrial Cleaning Services Limited | Construction | 2003 |
| Dominik Cieslik Ltd | Transport & logistics | 2022 |
| Dorford Electrical Limited | Manufacturing | 1999 |
| Dosanjh Real Estate Limited | Real estate | 2022 |
| Dostia C.I.C. | Financial services | 2025 |
| Dpbp Ltd | Transport & logistics | 2011 |
| DR Karan Jutlla Ltd | Education | 2021 |
| DR Simm Ltd | Health & social care | 2023 |
| Dravo Ltd | Manufacturing | 2020 |
| Dream Leic Ltd | Wholesale & retail | 2025 |
| Drillcore (Wednesbury) Limited | Construction | 1991 |
| Driver Task Transport Ltd | Transport & logistics | 2025 |
| Driveway & Patio Masters Ltd | Administrative & support | 2023 |
| DS Const Ltd | Construction | 2025 |
| DSGS24 Ltd | Transport & logistics | 2024 |
| DT ASH Ltd | Construction | 2025 |
| DTC Business Services Ltd | Construction | 2025 |
| DTS Business Services Ltd | Professional & scientific | 2026 |
| Dudley Port Lease Ltd | Real estate | 2023 |
| Dudley Road Meat Centre Ltd | Wholesale & retail | 2025 |
| Duggal Ltd | Transport & logistics | 2020 |
| Dumy Ltd | Transport & logistics | 2017 |
| Durbin Metal Industries Limited | Wholesale & retail | 1982 |
| Dutch Corporations UK Ltd | Wholesale & retail | 2025 |
| DWS Logistics Ltd | Transport & logistics | 2025 |
| Dwtl Ltd | Construction | 2025 |
| DZR Enterprises Ltd | Transport & logistics | 2023 |
| E & W Bookkeepers Limited | Professional & scientific | 2011 |
| E Bargains Ltd | Wholesale & retail | 2024 |
| E.C.L. Events Ltd | Other services | 2010 |
| E.Hamilton Ltd | Transport & logistics | 2026 |
| E.W Installations Limited | Construction | 2016 |
| Earthworks Demolition Remediation (EDR) Limited | Professional & scientific | 2020 |
| East Africa Corporate Reservations Limited | Hospitality | 2021 |
| East Shield Service Limited | Wholesale & retail | 2023 |
| Eastern European Mini Market International Ltd | Wholesale & retail | 2026 |
| Easy UK Prints Ltd | Manufacturing | 2025 |
| Easypay Car Finance Limited | Wholesale & retail | 2016 |
| EB Praise Property Services Limited | Construction | 2024 |
| EB Rail & Construction Ltd | Construction | 2025 |
| Ebecos Ltd | Wholesale & retail | 2022 |
| Ebenezer Motors Ltd | Wholesale & retail | 2016 |
| Ebenezer Stone Group Limited | Real estate | 2019 |
| Ebenezer Stone Holdings Limited | Real estate | 2019 |
| Ebenezer Stone Limited | Real estate | 2019 |
| Eco Parts Wash Ltd | Manufacturing | 2020 |
| Eco'D UP Ltd | Construction | 2024 |
| Eco-Nomic Systems UK Limited | Construction | 2007 |
| Ecolink Express Logistics Limited | Transport & logistics | 2025 |
| Edgy Constructions Ltd | Construction | 2025 |
| Edmo Group Limited | Manufacturing | 2016 |
| Edmo Limited | Manufacturing | 1978 |
| Edmo Powder Coatings Ltd. | Manufacturing | 1988 |
| Edushelter Limited | Construction | 2023 |
| Edward Jones Parts Ltd | Wholesale & retail | 2025 |
| Edward Lloyd Ltd | Wholesale & retail | 2011 |
| Efilda Healthcare Ltd | Health & social care | 2023 |
| EGN Haulage Limited | Construction | 2020 |
| Ejhwalsalloldpark Ltd | Households | 2019 |
| Ejjj Events Ltd | Arts & recreation | 2025 |
| Ekspres Limited | Construction | 2018 |