| Equip to Empower Ltd | Health & social care | 2019 |
| Equipobase Limited | Information & communication | 2014 |
| Equit Consult Limited | Professional & scientific | 2014 |
| Equitable Homes Project Community Interest Company | Administrative & support | 2026 |
| Equite Consulting Limited | Information & communication | 2008 |
| ER Valeting Centre (UK) Ltd | Other services | 2018 |
| Erade Ltd | Wholesale & retail | 2021 |
| Eragas Ltd | Wholesale & retail | 2022 |
| Erakab Consulting Ltd | Information & communication | 2025 |
| Erasure Integral Limited | Information & communication | 2016 |
| Eraya Solutions Limited | Information & communication | 2009 |
| Erdington Medical Ltd | Health & social care | 2023 |
| Erea Properties Limited | Real estate | 2015 |
| Eresos Property Limited | Financial services | 2025 |
| Erik Construction (London) Limited | Construction | 2015 |
| Erika Turner Limited | Health & social care | 2010 |
| Erini Consulting Limited | Professional & scientific | 2022 |
| Ernest Park Ltd | Construction | 2013 |
| ERP Project Consulting Limited | Information & communication | 2015 |
| ERS Consultancy Limited | Administrative & support | 2008 |
| ERS Management Ltd. | Other services | 2008 |
| ES Architecture Ltd | Professional & scientific | 2014 |
| ES Broadcast Hire Ltd | Administrative & support | 2012 |
| ES Broadcast Limited | Administrative & support | 2020 |
| ES Broadcast S.I. Limited | Information & communication | 2019 |
| ES Media Group Limited | Administrative & support | 2002 |
| ES3 Group Ltd | Administrative & support | 2024 |
| Esay London Ltd | Wholesale & retail | 2024 |
| Escoms Telecoms Installations Ltd | Information & communication | 2025 |
| Esenza Ltd | Information & communication | 2024 |
| Eshalve Limited | Wholesale & retail | 2025 |
| Eshan Kanz Ltd | Hospitality | 2020 |
| Eshcol Investments Ltd | Professional & scientific | 2024 |
| ESM Capital Group Limited | Real estate | 2023 |
| Esmeas Ltd | Wholesale & retail | 2022 |
| Esmerillion Associates Limited | Professional & scientific | 1994 |
| Esmmg Ltd | Information & communication | 2026 |
| Espharmac Limited | Wholesale & retail | 2024 |
| Esplanade Online Ltd | Information & communication | 2018 |
| Esquare Consulting PVT Ltd | Professional & scientific | 2009 |
| ESS Carpet Cleaning Ltd | Administrative & support | 2026 |
| ESS N Eich Ltd | Wholesale & retail | 2025 |
| ESS Window Cleaning Ltd | Administrative & support | 2023 |
| Essen Valuers Limited | Administrative & support | 2007 |
| Essence Relocations UK Ltd | Hospitality | 2021 |
| Essentia Market Ltd | Wholesale & retail | 2025 |
| Essential IT Solutions Limited | Information & communication | 2009 |
| Essential Medical Solutions Ltd | Health & social care | 2024 |
| Essential Training Ltd | Education | 2025 |
| Essential Trendz Ltd | Wholesale & retail | 2023 |
| Essential Workhouse Limited | Information & communication | 2018 |
| Essentials KAS Ltd | Information & communication | 2022 |
| Essex Cars & Parts Ltd | Wholesale & retail | 2024 |
| Essex Garment Repairs Ltd | Other services | 2025 |
| Essex General Medical Services Limited | Health & social care | 2006 |
| Estai Estates Limited | Real estate | 2020 |
| Estai Holdings Limited | Financial services | 2021 |
| Estai Properties Limited | Real estate | 2018 |
| Estar Medical UK Limited | Manufacturing | 2020 |
| Estate Head Office Investments Limited | Administrative & support | 2017 |
| Estatesmen Ltd | Real estate | 2024 |
| Esthetic City Ltd | Other services | 2014 |
| Estokova Ltd | Real estate | 2024 |
| ET Double Glazing Ltd | Construction | 2026 |
| ET Omni Sales Consultants Ltd | Professional & scientific | 2025 |
| ETC Property Services Ltd | Information & communication | 2023 |
| Etch Squared Limited | Information & communication | 2011 |
| Etchersend Ltd | Extraterritorial | 2022 |
| Etera INV UN Limited | Financial services | 2025 |
| Eternity Community CIC | Education | 2024 |
| Ethanalex Ltd | Other services | 2012 |
| Ether AI Ltd | Information & communication | 2023 |
| Ethereal Films Ltd | Professional & scientific | 2026 |
| Ethesy Ltd | Wholesale & retail | 2007 |
| Ethicx Ltd | Manufacturing | 2023 |
| ETI Dent Limited | Health & social care | 2018 |
| ETL Informatics Ltd | Information & communication | 2011 |
| Eton Vista Limited | Real estate | 1992 |
| ETS Electrical Ltd | Construction | 2025 |
| Etsq Consulting Limited | Information & communication | 2021 |
| EU Sustainable Project Group Ltd | Manufacturing | 2021 |
| Eubel Consulting Limited | Information & communication | 2026 |
| Eudamon Limited | Professional & scientific | 2017 |
| Eugene (London) Company Limited | Wholesale & retail | 2007 |
| Eugene Risdon Post Ltd | Information & communication | 2020 |
| Eukrasis Ltd | Information & communication | 2025 |
| Euphris Ltd | Wholesale & retail | 2019 |
| Eurasia Capital Construction Limited | Construction | 2024 |
| Eurasia Shipping and Trading Ltd | Wholesale & retail | 2020 |
| Eurica Cleaning Company Ltd | Administrative & support | 2025 |
| Euro Food & Wine Watford Ltd | Wholesale & retail | 2013 |
| Euro Gulf Property Limited | Real estate | 2023 |
| Euro Security and Facilities Management Ltd | Administrative & support | 2024 |
| Eurohandle Ltd | Wholesale & retail | 2018 |
| Eurohaven Accountants Limited | Professional & scientific | 2012 |
| Eurohaven Holdings Ltd | Real estate | 2017 |
| Eurohaven Trading Ltd | Wholesale & retail | 2022 |
| Eurosupply.Co.Uk Ltd | Manufacturing | 2023 |
| Eutopia Creations Ltd | Professional & scientific | 2023 |
| EV Tech Solutions Ltd | Information & communication | 2018 |