| Superbia Automotive Ltd. | Wholesale & retail | 2013 |
| Superbia Body Works Ltd | Wholesale & retail | 2021 |
| Superior Touch Cleaning Services Ltd | Other services | 2026 |
| Supporting Minds Consultancy Limited | Health & social care | 2022 |
| Supreme Roofing Limited | Construction | 2023 |
| Surefix Home Improvements Limited | Construction | 2000 |
| Surf Shack Cafe Limited | Hospitality | 2014 |
| Surface Guard Limited | Wholesale & retail | 2006 |
| Surmount Limited | Real estate | 2000 |
| Sursum Limited | Health & social care | 1988 |
| Surveying Recruitment Limited | Administrative & support | 2024 |
| Sussex Archaeology and History Ltd | Education | 2011 |
| Sussex Catering Limited | Hospitality | 2018 |
| Sussex Property Innovations Ltd | Construction | 2024 |
| Sussex Roofing and Guttering Specialists Ltd | Construction | 2026 |
| Sussex Urology Ltd | Health & social care | 2018 |
| Sustain Heating Ltd | Construction | 2025 |
| Sutter's Mill Ltd | Wholesale & retail | 2014 |
| SV Beyond Ltd | Professional & scientific | 2010 |
| SV Construction Ltd | Construction | 2007 |
| Sw@Lestons Consultancy Limited | Professional & scientific | 2025 |
| Swaffield Lilliput Ltd | Other services | 2018 |
| Swaffields Upton Ltd | Other services | 2021 |
| Swaffields Wimborne Ltd | Other services | 2018 |
| Swan Court RTM Company Limited | Households | 2019 |
| Sweat Group Ltd | Education | 2011 |
| Sweet and Tart Ltd | Manufacturing | 2010 |
| Sweethearts Preschool Ltd | Education | 2020 |
| Sweetselfiespot Ltd | Wholesale & retail | 2020 |
| Swift Building & Property Services Ltd | Construction | 2021 |
| Swift Floors Limited | Construction | 2011 |
| Swift Mortgages (Fareham) Limited | Financial services | 2007 |
| Swiftpark Limited | Wholesale & retail | 1985 |
| Swim Stop Limited | Wholesale & retail | 2000 |
| Swimming Babies Limited | Education | 2013 |
| Swimpix Limited | Information & communication | 2010 |
| Switch MK Ltd | Real estate | 2016 |
| Switchline Electrical Ltd | Construction | 2020 |
| Swizio Ltd | Wholesale & retail | 2020 |
| SWL NDT Ltd | Extraterritorial | 2010 |
| SWL Rope Lifting and Testing Limited | Manufacturing | 2007 |
| Swonsong Limited | Information & communication | 2014 |
| SWP Compressed Air Services Ltd | Administrative & support | 2023 |
| SWW Transit Limited | Transport & logistics | 2019 |
| Syed Takeaway Limited | Hospitality | 2019 |
| Sync Savings Limited | Administrative & support | 2023 |
| Sync Technologies Limited | Information & communication | 2025 |
| Synctech Limited | Information & communication | 2018 |
| Syndicate Property Development Ltd | Construction | 2018 |
| Synergywifi Limited | Information & communication | 2025 |
| Synthetic Sensations Ltd | Manufacturing | 2022 |
| Systegrated Limited | Professional & scientific | 2021 |
| Systemic Growth Ltd | Professional & scientific | 2017 |
| Systemup Ltd | Information & communication | 2013 |
| Syze Developments Ltd | Construction | 2022 |
| T & G Guildford Limited | Other services | 2013 |
| T & K Installs Ltd | Construction | 2023 |
| T & S Hill Holdings Limited | Financial services | 2008 |
| T & S Hill Limited | Transport & logistics | 2009 |
| T & T Vehicle Centre Limited | Wholesale & retail | 2021 |
| T a Potter Installations Limited | Construction | 2008 |
| T Avory Management Services Limited | Professional & scientific | 2013 |
| T B Trophies Limited | Manufacturing | 2007 |
| T by the Sea Limited | Hospitality | 2023 |
| T C Energy Ltd | Construction | 2008 |
| T D Farriers Ltd | Agriculture & fishing | 2022 |
| T H Exhibitions Ltd | Professional & scientific | 2004 |
| T J Ventilation Limited | Construction | 2013 |
| T K B Property Services Ltd | Construction | 2022 |
| T L H Construction Limited | Construction | 2017 |
| T Lofts Ltd | Construction | 2022 |
| T Palmer Plumbing and Heating Limited | Construction | 2012 |
| T Piper Property Maintenance Limited | Construction | 2005 |
| T S Air Ltd | Construction | 2026 |
| T U Rail Services Ltd | Construction | 2024 |
| T W Contracting Limited | Construction | 2014 |
| T&C Sharpe Management Services Limited | Financial services | 2012 |
| T&T UK Holdings Ltd | Professional & scientific | 2024 |
| T.H Installations Southern Ltd | Construction | 2024 |
| T.H. Marine Ltd | Information & communication | 2022 |
| T.L.B Projects Ltd | Construction | 2018 |
| T3 Medical Services Limited | Health & social care | 2011 |
| T333 Soulfood Ltd | Hospitality | 2023 |
| TA Crookhorn Limited | Hospitality | 2023 |
| Tactical Defence Solutions Ltd | Professional & scientific | 2006 |
| Taeliyah Limited | Professional & scientific | 2025 |
| TAG (Hampshire) Ltd | Construction | 2019 |
| TAG Team Limited | Information & communication | 2025 |
| Tai-Robics Ltd | Health & social care | 2015 |
| Tailor Consultancy Services Ltd | Professional & scientific | 2013 |
| Tailored Gifts Limited | Wholesale & retail | 2014 |
| Tajj Solutions Limited | Administrative & support | 2024 |
| Taka Properties Ltd | Real estate | 2024 |
| Talent Axis Ltd | Information & communication | 2026 |
| TALK2TALK Communications Ltd | Wholesale & retail | 2013 |
| Talking LAB Ltd | Information & communication | 2018 |
| Tally Shed Limited | Professional & scientific | 2013 |
| TAN & Envy Limited | Other services | 2012 |
| Tan-Sea Limited | Health & social care | 2014 |
| Taniwha Properties Limited | Real estate | 2019 |