| Reuben and LOX Limited | Hospitality | 2025 |
| Revamp Southern Ltd | Construction | 2016 |
| Revcoat Technologies Limited | Manufacturing | 2006 |
| Revealedcouture Ltd | Wholesale & retail | 2025 |
| Revelation Detailing Ltd | Wholesale & retail | 2025 |
| Reverie Homeware Limited | Wholesale & retail | 2024 |
| Review (Cowplain) Limited | Other services | 2001 |
| Review Hairdressing Limited | Other services | 2025 |
| Review Holdings Limited | Professional & scientific | 2017 |
| Review Properties Limited | Real estate | 2001 |
| Revive Balustrade Ltd | Construction | 2021 |
| Revive Southsea Ltd | Health & social care | 2022 |
| Revnet Ltd | Information & communication | 2026 |
| Revolution Clinic Limited | Health & social care | 2026 |
| Revolutionary Cards Limited | Manufacturing | 2024 |
| REW (Holdings) Limited | Real estate | 2019 |
| Reynolds Electrical Southern Ltd | Construction | 2024 |
| Reynolds Technical Solutions Ltd | Professional & scientific | 2025 |
| Rezenate Ltd | Administrative & support | 2024 |
| RF Forklift Training Limited | Other services | 2019 |
| Rfidx Ltd | Information & communication | 2025 |
| RG Anchorstone Properties Ltd | Construction | 2025 |
| RG215RZ29 Ltd | Real estate | 2024 |
| RG248SN Ltd | Real estate | 2026 |
| RGD Property Ltd | Real estate | 2023 |
| RGM Electrical Services Limited | Construction | 2016 |
| RGV Services Ltd | Wholesale & retail | 2022 |
| Rhino Surfacing Limited | Construction | 2019 |
| Rhoop Design Limited | Manufacturing | 2020 |
| Rhubarb Events Ltd | Administrative & support | 2004 |
| Ribuah Cleaning Services Ltd | Administrative & support | 2025 |
| Ribuah Healthcare Ltd | Public administration | 2018 |
| Ricebridge Limited | Information & communication | 2016 |
| Richard Bassford Bespoke Estate Agency Limited | Real estate | 2021 |
| Richard Hamilton Management Services Limited | Financial services | 2016 |
| Richard J Phillips Sales Solutions Limited | Other services | 2026 |
| Richmond & James Ltd | Wholesale & retail | 2006 |
| Richmond House (Southampton) Investments Ltd | Real estate | 2012 |
| Richmond Mortgages Ltd | Financial services | 2024 |
| Ridgeline Roofing Solutions Ltd | Construction | 2026 |
| Ridgeway Land Holdings Limited | Financial services | 2019 |
| Ridgeway Roofing & Property Maintenance Ltd | Construction | 2023 |
| Rids Engineering Ltd | Professional & scientific | 2024 |
| Right Bond Ltd | Wholesale & retail | 2022 |
| Right Direction Counselling Services Ltd | Health & social care | 2023 |
| Right Track Chiropractic Limited | Health & social care | 2026 |
| Ring and Bring Limited | Wholesale & retail | 2006 |
| Rising Tyde Ltd | Professional & scientific | 2017 |
| Risk Assurance Management Limited | Financial services | 1977 |
| Ritepick Limited | Administrative & support | 2024 |
| Riva 6 Beauty Limited | Other services | 2020 |
| Rivair Air Conditioning Limited | Construction | 2023 |
| River Path Associates Limited | Professional & scientific | 1997 |
| Riverside Mews Limited | Extraterritorial | 2013 |
| Riversource Services Ltd. | Health & social care | 2022 |
| Riverview Developments Limited | Professional & scientific | 1998 |
| Rizkam Limited | Financial services | 2025 |
| RJB Marketing Consultancy Limited | Professional & scientific | 2011 |
| RJM Electrical Limited | Construction | 2000 |
| RJW Contracting Ltd | Manufacturing | 2014 |
| Rkld Limited | Wholesale & retail | 2026 |
| RLA Marine Electrical Ltd | Construction | 2025 |
| RM Finch Limited | Information & communication | 2012 |
| RMC Anodising Limited | Manufacturing | 2023 |
| RMD Property Investments Ltd | Real estate | 2026 |
| Rmgentry Design Ltd | Administrative & support | 2017 |
| Rmsb Investments Limited | Financial services | 2025 |
| RMT Property Renovations Ltd | Construction | 2025 |
| Roach Investments Ltd | Financial services | 2025 |
| Road Sense Driving Services Ltd | Education | 2023 |
| Roadsafe Europe Limited | Education | 2005 |
| Roadwise Driving School Limited | Education | 2011 |
| ROB Carr Personal Training Ltd | Other services | 2022 |
| Robel Developments Limited | Construction | 2007 |
| Robert Boyle Associates Limited | Professional & scientific | 2019 |
| Robert Brown Associates Limited | Professional & scientific | 2019 |
| Robert Brown Golf Management Limited | Wholesale & retail | 2003 |
| Robert Brown Holdings Limited | Professional & scientific | 2003 |
| Roberts Decorators Ltd | Construction | 2026 |
| Roberts Partners Limited | Professional & scientific | 2009 |
| Robin Property Investments LLP | | 2015 |
| Robin Winch Consultancy Ltd | Professional & scientific | 2016 |
| Robinson Financial Solutions Ltd | Financial services | 2013 |
| Robust Health Limited | Health & social care | 2011 |
| Robust Strength Ltd | Wholesale & retail | 2026 |
| Rocabella Enterprises Ltd | Construction | 2024 |
| Rock N Romance Limited | Wholesale & retail | 2015 |
| Rock Zero Group Ltd | Construction | 2016 |
| Rocket Cleaning Supplies Limited | Wholesale & retail | 2025 |
| Rocket Computer Services Limited | Information & communication | 2007 |
| Rocketts of Denmead Limited | Wholesale & retail | 2012 |
| Rocketts Wraps & Graphics Ltd | Professional & scientific | 2018 |
| Rocking Parties Ltd | Administrative & support | 2025 |
| Rockland Property Limited | Real estate | 2023 |
| Rocks Group Restaurants Limited | Hospitality | 2026 |
| Rockstone 20 - 20 Ltd | Real estate | 2021 |
| Rockys Haven Ltd | Extraterritorial | 2022 |
| Roco Structural Engineers Limited | Professional & scientific | 2014 |
| Roden Capital Investments Ltd | Real estate | 2026 |
| Rodex Property Services Limited | Construction | 2026 |