| ELK Digital Limited | Information & communication | 2021 |
| Elley Industrial Roofing Ltd | Construction | 2019 |
| Ellie Amelia Hair Extensions Ltd | Other services | 2026 |
| Ellie EM & Co Ltd | Other services | 2016 |
| Ellie Jade Fitness Ltd | Arts & recreation | 2022 |
| ELM Park Management Ltd | Professional & scientific | 2024 |
| Elsol Limited | Information & communication | 2011 |
| Elvis Enterprises Limited | Wholesale & retail | 2024 |
| Emanta Limited | Other services | 2019 |
| Ember Hospitality (Catering) Limited | Hospitality | 2025 |
| Ember Hospitality Ltd | Hospitality | 2025 |
| Embers Bushcraft Limited | Education | 2014 |
| Emerald Artificial Grass Ltd | Administrative & support | 2022 |
| Emerging Property Limited | Real estate | 2009 |
| Emerson Holdings Limited | Financial services | 2009 |
| EMF Group Limited | Extraterritorial | 2025 |
| EMF Roofing Ltd | Construction | 2019 |
| EMF Scaffolding Limited | Construction | 2025 |
| Emily Hall Ltd | Real estate | 2026 |
| Emirax Ltd | Wholesale & retail | 2025 |
| Emmis Rail Limited | Construction | 2022 |
| EMP Laser Welding Consultants Limited | Professional & scientific | 2026 |
| EMP London Ltd | Construction | 2019 |
| Empire Cooling Ltd | Professional & scientific | 2026 |
| Empower ME Occupational Therapy Ltd | Health & social care | 2025 |
| Empowered Leadership Consultancy Limited | Education | 2026 |
| Emra Consult Limited | Wholesale & retail | 2016 |
| Emsworth Carpet Cleaning Ltd | Administrative & support | 2025 |
| Emsworth Textile Cleaners Limited | Other services | 2012 |
| Emure & Co Limited | Other services | 2024 |
| En-Fuse Electrical Limited | Construction | 2013 |
| Enasni Ltd | Health & social care | 2019 |
| Enchanting Care Limited | Health & social care | 2015 |
| Encore Construction Ltd | Construction | 2025 |
| Encountering Existence Ltd | Health & social care | 2020 |
| Endless Digital Ltd | Wholesale & retail | 2020 |
| Endless Flooring Ltd | Wholesale & retail | 2021 |
| Endy Builders Limited | Construction | 2002 |
| Eneavour Limited | Professional & scientific | 2008 |
| Energy Management & Sustainability Services Ltd | Professional & scientific | 2024 |
| Engage IT Services Ltd | Information & communication | 2018 |
| Engauge Facilities Management Ltd | Professional & scientific | 2024 |
| Engcad Solutions Limited | Professional & scientific | 2018 |
| Engineer Booking Limited | Construction | 2022 |
| Engineering Technology Systems Limited | Other services | 2015 |
| England Joinery Limited | Construction | 2003 |
| English Tile Company Limited | Extraterritorial | 2005 |
| Enhanced Roofing Services Southern Ltd | Construction | 2026 |
| Enigma Performance Limited | Financial services | 2020 |
| Enigma Pictures Limited | Information & communication | 2023 |
| Enigma Portfolio Management Limited | Professional & scientific | 2017 |
| Enigma Powerboats Ltd | Manufacturing | 2021 |
| Enjoy Tree Care Ltd | Administrative & support | 2015 |
| Enmas Emobility Ltd | Professional & scientific | 2025 |
| Ennead Homes Limited | Construction | 2023 |
| Enrichment Coaching Limited | Professional & scientific | 2019 |
| Entelechyrop Limited | Wholesale & retail | 2025 |
| Enterprise Publishing Ventures Limited | Wholesale & retail | 2025 |
| Entertainment Events Ltd | Arts & recreation | 2022 |
| Enviro Mechanical Services Ltd | Construction | 2024 |
| Enviroboost Limited | Manufacturing | 2018 |
| Envirodeck Limited | Construction | 2019 |
| Envirokit Limited | Professional & scientific | 2026 |
| Environmental Management & Monitoring Assistance Ltd | Professional & scientific | 2023 |
| EO Properties 2017 Ltd | Real estate | 2017 |
| EOX Limited | Extraterritorial | 2009 |
| Epic Cars Limited | Wholesale & retail | 2017 |
| Epiphyte 360 Holdings Limited | Professional & scientific | 2010 |
| Epmg Ltd | Information & communication | 2025 |
| Equatis Limited | Professional & scientific | 2009 |
| Equine Holdings Limited | Manufacturing | 2023 |
| Equipment Distribution Limited | Wholesale & retail | 2015 |
| Equity Real Estate (Delta) Ltd | Real estate | 2014 |
| Erik Sanchez Sourcing Limited | Administrative & support | 2024 |
| Erma's PPE Ltd | Manufacturing | 2023 |
| ERRANDS4U Ltd | Transport & logistics | 2020 |
| Errenas (NCC) Limited | Financial services | 2025 |
| Esbr Projects Ltd | Construction | 2025 |
| Escapeinto Ltd | Information & communication | 2025 |
| Esdl - UK Limited | Professional & scientific | 2016 |
| Esen.Tials Beauty Limited | Manufacturing | 2025 |
| Esme White Limited | Health & social care | 2025 |
| ESP Operations Ltd | Information & communication | 2023 |
| Espresso Glow Company Limited | Other services | 2024 |
| Essex Cars Ltd. | Wholesale & retail | 2014 |
| Esto Logistics Ltd | Transport & logistics | 2026 |
| Esurio Store Ltd | Wholesale & retail | 2026 |
| Eternal Muse Ltd | Wholesale & retail | 2021 |
| Ether Environmental Ltd | Water & waste | 2025 |
| Ethicoe Sales Management Ltd | Professional & scientific | 2013 |
| ETI Cleaning Services Ltd | Administrative & support | 2017 |
| Etienne's Estates Limited | Real estate | 2026 |
| ETV FZ Limited | Information & communication | 2020 |
| Euphonic Music Limited | Wholesale & retail | 2025 |
| European Exhaust & Catalyst Limited | Manufacturing | 1997 |
| European Worldwide Ltd | Wholesale & retail | 2019 |
| Eurotec 97 Limited | Wholesale & retail | 1997 |
| Eurotech Fire Systems Limited | Administrative & support | 2009 |
| Eurotech Holdings Ltd | Real estate | 2026 |
| Euroville Limited | Professional & scientific | 1998 |