| DE Commercial Consultancy Ltd | Professional & scientific | 2017 |
| DE Legal Services Ltd | Administrative & support | 2020 |
| DE Leonibus Holdings Ltd | Real estate | 2020 |
| DEA Financial Services Ltd | Professional & scientific | 2025 |
| Dead Angry Printing Company Ltd | Wholesale & retail | 2022 |
| Deadmad Ltd | Information & communication | 2026 |
| Dean KAY Plastering Limited | Construction | 2018 |
| Deanborgia Limited | Professional & scientific | 2013 |
| Deantech Solutions Limited | Professional & scientific | 2007 |
| Dearman Engineering Limited | Professional & scientific | 2018 |
| Deathcurse Creative Limited | Administrative & support | 2016 |
| DEB Parrington & SON Limited | Manufacturing | 1994 |
| Debbie Lowe Limited | Professional & scientific | 2014 |
| Deborah ANN Hairdressing Limited | Other services | 2018 |
| Deborah Grayson Coaching Ltd | Professional & scientific | 2021 |
| Debt Advice Bureau Ltd | Other services | 2019 |
| Debt Done Limited | Education | 2025 |
| Decade Engineering Systems Ltd | Professional & scientific | 2020 |
| Decarbonwise Ltd | Other services | 2022 |
| Decarboserv Limited | Administrative & support | 2025 |
| Decco Holdings UK Limited | Agriculture & fishing | 2021 |
| Decentral Search Ltd | Information & communication | 2022 |
| Deckiaron Consultant Ltd | Information & communication | 2012 |
| Decking Warrington Limited | Administrative & support | 2024 |
| Decking, Fencing and Gates Warrington Limited | Extraterritorial | 2026 |
| Deconstruction Records Limited | Extraterritorial | 2010 |
| DECOR8 - Painting & Design Services Ltd | Construction | 2022 |
| Decortie UK Ltd | Wholesale & retail | 2017 |
| Decsc Ltd | Information & communication | 2022 |
| DEE Enterprise Excellence Limited | Administrative & support | 2013 |
| DEE Murphy Ltd | Construction | 2016 |
| Deeba Anandan Ltd | Health & social care | 2016 |
| Deecpe Project Management Ltd | Administrative & support | 2021 |
| Deegei Consultancy Limited | Administrative & support | 2016 |
| Deema Holdings Limited | Real estate | 2017 |
| Deemantech Ltd | Professional & scientific | 2018 |
| Deen Alvi Ltd | Professional & scientific | 2018 |
| Deeper Design Ltd | Professional & scientific | 2017 |
| Deepocean Engineering Solution Ltd | Administrative & support | 2012 |
| Deepsee.Ai Europe Ltd | Information & communication | 2021 |
| Deeray Consulting Limited | Information & communication | 2017 |
| Defence Aviation Solutions Limited | Professional & scientific | 2017 |
| Defence Limited | Administrative & support | 2015 |
| Definteco Technical Management Limited | Professional & scientific | 2011 |
| Degali Properties Limited | Real estate | 2023 |
| Dehavilland Planning Limited | Professional & scientific | 2017 |
| Deian Thomas Ltd | Administrative & support | 2022 |
| Dejavoo Barber Ltd | Other services | 2022 |
| Dekoo Limited | Professional & scientific | 2011 |
| Dekoo Properties Limited | Real estate | 2014 |
| Dekorglass Dzialdowo Limited | Administrative & support | 2017 |
| DEL Gustavo Ltd | Hospitality | 2022 |
| Delacey Properties Limited | Real estate | 2016 |
| Delamelectrical Limited | Professional & scientific | 2025 |
| Delan Properties Limited | Real estate | 2020 |
| Delfina Engineering Limited | Manufacturing | 2019 |
| Delicate Persuasion Limited | Administrative & support | 2015 |
| Delight Property Ltd | Real estate | 2017 |
| Deliro Market Ltd | Wholesale & retail | 2025 |
| Deliverit Consulting Ltd | Administrative & support | 2013 |
| Delivery Technology Solutions Ltd | Administrative & support | 2022 |
| Delman Properties Limited | Real estate | 2016 |
| Delooze Limited | Real estate | 1970 |
| Delphfields Court Management Limited | Households | 2015 |
| DELROB78 Limited | Administrative & support | 2015 |
| Delta Glazing Limited | Administrative & support | 2003 |
| Delta Lima Ltd | Administrative & support | 2019 |
| Delta Offshore Ltd | Professional & scientific | 2018 |
| DELTA5 Properties Ltd | Real estate | 2024 |
| Deltashore Limited | Administrative & support | 2020 |
| Deltatex Consulting Limited | Information & communication | 2020 |
| Delv P&C Limited | Professional & scientific | 2024 |
| Demmy the Bookmaker Limited | Arts & recreation | 1993 |
| Democracy Counts Holdings Limited | Financial services | 2020 |
| Democracy Counts Limited | Information & communication | 2009 |
| Democracy Global Ltd | Financial services | 2011 |
| Demolition Training Services Limited | Construction | 2017 |
| Denali Estates Limited | Construction | 2008 |
| Denali Homes Limited | Construction | 2005 |
| Dendan Systems Limited | Information & communication | 2023 |
| Dendrium ST Limited | Professional & scientific | 2025 |
| Denesh & Sons Ltd | Administrative & support | 2023 |
| Denis Egan Build Limited | Construction | 2019 |
| Denkyem Engineering Consultants Limited | Professional & scientific | 2019 |
| Denmart Group Ltd | Wholesale & retail | 2023 |
| Dens Joedan Limited | Administrative & support | 2024 |
| Densham Homes Limited | Construction | 2026 |
| Dent MAN DAN Ltd | Wholesale & retail | 2025 |
| Dental Flag Limited | Health & social care | 2020 |
| Dentice Limited | Health & social care | 2015 |
| Dentinology Ltd | Health & social care | 2015 |
| Dentissy Limited | Health & social care | 2025 |
| Dentros Real Estate UK Limited | Real estate | 2025 |
| Dereje Worku Engineering Limited | Administrative & support | 2011 |
| Derek Hallwood Window Cleaning Ltd | Other services | 2016 |
| Derek Houghton Limited | Professional & scientific | 2004 |
| Dermalux Home Limited | Wholesale & retail | 2026 |
| Descoberta Ltd | Administrative & support | 2019 |
| Design & Planning Services (Warrington) Ltd | Professional & scientific | 2011 |
| Design and Building Ltd | Construction | 2023 |