| Dents Limited | Extraterritorial | 1962 |
| Design to Mine Consulting Limited | Mining & quarrying | 2010 |
| Development Ecology Consulting Ltd | Professional & scientific | 2012 |
| Deverill IP Limited | Professional & scientific | 2012 |
| Dewey Day Spa Limited | Arts & recreation | 2025 |
| Dewhurst Dent P.L.C. | Manufacturing | 1919 |
| Diamond Home Property Management Limited | Real estate | 2017 |
| Diamond Home Services (SW) Limited | Other services | 2014 |
| Different Dynamics Limited | Professional & scientific | 2002 |
| Dilton Developments Limited | Construction | 2021 |
| Dilton Holdings Limited | Financial services | 2020 |
| Direct Candles Limited | Wholesale & retail | 1998 |
| DIS Consulting Limited | Professional & scientific | 2023 |
| Divine Balance Dwellings Ltd | Construction | 2026 |
| DOA Exploration Limited | Mining & quarrying | 2009 |
| DOC2POST Ltd | Information & communication | 2019 |
| Doit Logistics Ltd | Transport & logistics | 2020 |
| Dolumi Limited | Real estate | 2019 |
| Dots Research Limited | Professional & scientific | 2018 |
| Downlands Tree Surgery Ltd | Agriculture & fishing | 2008 |
| DPA Transport Limited | Transport & logistics | 2022 |
| DR Vicky Sutton Limited | Health & social care | 2014 |
| Driveway Motoring Ltd. | Wholesale & retail | 2015 |
| Drumattic Limited | Wholesale & retail | 2018 |
| DSB Plastering Bath Ltd | Construction | 2026 |
| Dtopvet Ltd | Extraterritorial | 2020 |
| DU Parcq Stables Limited | Professional & scientific | 2025 |
| DUO (U.K.) Limited | Education | 1982 |
| Dynamic Therapy Solutions UK Ltd | Other services | 2021 |
| D’Ambrumenil LLP 125 Ltd | Professional & scientific | 2022 |
| EAR to Clear Ltd | Health & social care | 2024 |
| East Farm (STP) Limited | Households | 1997 |
| East Hill Farm Limited | Real estate | 2009 |
| Eastleigh Court Limited | Real estate | 2014 |
| Eastleigh Stables Limited | Real estate | 2014 |
| Ebony Property Holdings Ltd | Real estate | 2022 |
| EG Designs Limited | Administrative & support | 2000 |
| Egbert Stone Project CIC | Education | 2024 |
| Ejcollins Ltd | Professional & scientific | 2021 |
| EJM Fitness Ltd | Transport & logistics | 2024 |
| Elec-Trick Limited | Extraterritorial | 2005 |
| ELEV8 Training and Selection Ltd | Professional & scientific | 2025 |
| Elias Property & Letting Services Ltd | Real estate | 2026 |
| Elite DPF Regeneration Ltd | Professional & scientific | 2016 |
| Elite Fascias Limited | Construction | 2012 |
| Elite Taxis (Dorset) Limited | Transport & logistics | 2023 |
| Elleavga Ltd | Wholesale & retail | 2025 |
| Ellie Stidolph Ltd | Professional & scientific | 2019 |
| Elrose Consulting Ltd | Professional & scientific | 2022 |
| Embads Ltd | Professional & scientific | 2020 |
| Emerson Healthcare Limited | Health & social care | 2019 |
| En-Abel Ltd | Professional & scientific | 2025 |
| Engineering Systems International Ltd | Professional & scientific | 2024 |
| English Rose Garden PUB Company Limited | Hospitality | 2018 |
| Ephemeral Brazil Ltd | Administrative & support | 2008 |
| Equinox Services (UK) Ltd | Construction | 1999 |
| Ericourt Inns Limited | Hospitality | 2020 |
| Euram Air Leases UK Limited | Administrative & support | 2021 |
| Eurocast Industries Limited | Manufacturing | 2014 |
| Everest Property Limited | Financial services | 2025 |
| Ewins Surveying Services Limited | Construction | 2016 |
| Exile Picture Productions Ltd | Information & communication | 2025 |
| Expert Prosthetic Services Ltd | Health & social care | 2019 |
| Eyesopen Window Covers Limited | Wholesale & retail | 2022 |
| Eynon Catering Limited | Hospitality | 2018 |
| F Tieman & Co Ltd | Construction | 2015 |
| F.J. Chalke (Holdings) Limited | Administrative & support | 2019 |
| F.K Motors Showroom Ltd | Wholesale & retail | 2025 |
| Factorum Community C.I.C. | Wholesale & retail | 2025 |
| Factorum Limited | Wholesale & retail | 2022 |
| Fairbeech Developments Limited | Construction | 2014 |
| Faraday Tutors Limited | Education | 2022 |
| Farleigh Masonry Limited | Manufacturing | 1986 |
| Farm XS Ltd. | Water & waste | 2007 |
| FBS Flues & Chimneys Limited | Construction | 2012 |
| FBS Flues Limited | Construction | 2008 |
| Fdlm Services Limited | Professional & scientific | 2019 |
| Fern Automobiles Ltd | Wholesale & retail | 2025 |
| FI Solutions Ltd | Information & communication | 2004 |
| Fieldconsultancyservices Ltd | Professional & scientific | 2020 |
| Fire Power Cloud Ltd | Information & communication | 2019 |
| First AID & Compliance Training Ltd | Education | 2016 |
| Fisherton Processing Limited | Agriculture & fishing | 2021 |
| Five Alpha Consulting Limited | Professional & scientific | 2020 |
| Fleet Cottage Limited | Extraterritorial | 2013 |
| Flintford Ltd | Professional & scientific | 2026 |
| FMV Consulting Limited | Public administration | 2016 |
| FND Site Engineers Ltd | Professional & scientific | 2024 |
| Foodpro Interims Limited | Professional & scientific | 2010 |
| Forging Futures Coaching Limited | Other services | 2023 |
| Fortis Umbrella Limited | Financial services | 2020 |
| Fortress Mere Limited | Real estate | 2015 |
| Fortress Norton Limited | Real estate | 2015 |
| Fortress Whitton Limited | Construction | 2014 |
| Forza Aviation Ltd | Transport & logistics | 2026 |
| Foster, Hawker, Jones Ltd | Hospitality | 2020 |
| Fownes Gloves Limited | Extraterritorial | 1935 |
| Frome Baby Connections CIC | Health & social care | 2021 |
| Frome Heating & Plumbing Limited | Construction | 2022 |
| Frome Interiors Limited | Professional & scientific | 2013 |