| Eminence Transportation Ltd | Transport & logistics | 2019 |
| Eminence Travel Ltd | Transport & logistics | 2025 |
| EML Projects Limited | Construction | 2024 |
| Emma Rose Consultants Limited | Wholesale & retail | 2018 |
| Emotions Cards & Gifts Limited | Wholesale & retail | 2002 |
| Emotive EYE Ltd | Information & communication | 2019 |
| EMP Motors Ltd | Wholesale & retail | 2024 |
| Empire Builder Ltd | Construction | 2025 |
| Empire Elec Limited | Manufacturing | 2020 |
| Empire Estates Group Ltd | Real estate | 2020 |
| Empire MOT & Service Centre Ltd | Wholesale & retail | 2008 |
| Empire Pizza & Kebab Ltd | Hospitality | 2026 |
| Empire Shipment Services Ltd | Extraterritorial | 2015 |
| Empire Shipping Agencies (UK) Ltd | Extraterritorial | 2018 |
| Empire Shipping Services Ltd | Extraterritorial | 2018 |
| Empower Builder Limited | Construction | 2025 |
| Empowered Restaurants Ltd | Information & communication | 2006 |
| Empowering AI Ltd | Professional & scientific | 2025 |
| Empress Fast Food Ltd | Hospitality | 2021 |
| Empwr Property Ltd | Real estate | 2025 |
| Emraur Limited | Financial services | 2025 |
| EMS European Limited | Manufacturing | 1998 |
| EMY Logistics Ltd | Transport & logistics | 2019 |
| EN BL Services Ltd | Manufacturing | 2017 |
| EN Walsall Limited | Hospitality | 2025 |
| ENA Travel Ltd | Transport & logistics | 2023 |
| Enamejewa Askar Productions Ltd | Arts & recreation | 2025 |
| END Construction Limited | Administrative & support | 2016 |
| END2END Homes Ltd | Real estate | 2023 |
| Endeavour Accounting Services Ltd | Professional & scientific | 2013 |
| Endeavour Coaches Limited | Transport & logistics | 2005 |
| Endobil Limited | Health & social care | 2021 |
| Enekio Ltd | Wholesale & retail | 2025 |
| Energize Solutions (UK) Limited | Administrative & support | 2007 |
| Energy Lighting & Compliance Limited | Professional & scientific | 2018 |
| Energy Performance Specialists Ltd | Professional & scientific | 2022 |
| Engage Support Services Ltd | Health & social care | 2025 |
| Engel Healthcare Limited | Health & social care | 2022 |
| Engineering & Technical Solutions Ltd | Professional & scientific | 2013 |
| ENH Walsall Limited | Hospitality | 2019 |
| Enhance Coaching & Aesthetics Limited | Professional & scientific | 2022 |
| Enns Investments Ltd | Real estate | 2022 |
| Enny Blossom Daycare Ltd | Health & social care | 2026 |
| Enoch Evans (Walsall) Limited | Professional & scientific | 1983 |
| Enoch Evans LLP | | 2010 |
| Ensec Group Limited | Manufacturing | 2018 |
| Enterprise Links Limited | Professional & scientific | 2011 |
| Enthermal Limited | Construction | 2025 |
| Entiro Ltd | Wholesale & retail | 2022 |
| Entwined Flowers Limited | Wholesale & retail | 2024 |
| Envee Sports Ltd | Wholesale & retail | 2015 |
| Enviro Facilities Services Limited | Construction | 2017 |
| Environan Solutions Limited | Professional & scientific | 2015 |
| Environmental Drain Services Limited | Water & waste | 1996 |
| Environmental Management Services Limited | Water & waste | 1996 |
| Enviropulse Ltd | Administrative & support | 2017 |
| Envision Distribution and Storage Ltd | Transport & logistics | 2018 |
| Envision Management Ltd | Wholesale & retail | 2019 |
| Envy Beauty Ltd | Other services | 2021 |
| Envy ME Aesthetics Ltd | Other services | 2024 |
| Envy Self Drive Ltd | Transport & logistics | 2015 |
| EO Partners Limited | Financial services | 2012 |
| Eoghan-Rose Capital Limited | Financial services | 2024 |
| EPANTISKOS70 Limited | Transport & logistics | 2019 |
| EPI (MID) Ltd | Households | 2021 |
| Epic Aesthetics Ltd | Other services | 2025 |
| Epic Consulting Services Ltd | Professional & scientific | 2022 |
| Episteme Group Limited | Professional & scientific | 2017 |
| Episteme Investment Partners Limited | Professional & scientific | 2016 |
| Episteme Management Services Limited | Hospitality | 2019 |
| Episteme Staffing Solutions Limited | Administrative & support | 2024 |
| Epoch One Limited | Health & social care | 2026 |
| Epson Properties Ltd | Real estate | 2025 |
| Equitek Limited | Manufacturing | 2017 |
| Equity Capitus Investments Ltd | Real estate | 2024 |
| Equity Capitus Ltd | Real estate | 2020 |
| ER Brothers Ltd | Hospitality | 2024 |
| ERA Housing Limited | Real estate | 2026 |
| Erdington Road Developments Limited | Construction | 2017 |
| Erft Limited | Professional & scientific | 2008 |
| Eric Haulage Ltd | Transport & logistics | 2018 |
| Ernest Thomas (Walsall) Limited | | 1953 |
| Erra Transport Ltd | Transport & logistics | 2025 |
| ES Cares Limited | Administrative & support | 2026 |
| ES KAI Ltd | Wholesale & retail | 2019 |
| Esakjee Ltd | Transport & logistics | 2023 |
| Escapade 30 Ltd | Construction | 2023 |
| Esege Limited | Manufacturing | 2011 |
| Esen Transport Ltd | Transport & logistics | 2022 |
| Esher Financial Planning Limited | Financial services | 2019 |
| Esher Homes WM Ltd | Real estate | 2021 |
| Esher Mortgages Ltd | Financial services | 2021 |
| Esher Property Management Ltd | Real estate | 2020 |
| Esher Real Estate Limited | Real estate | 2019 |
| Esquires&Gentry Limited | Professional & scientific | 2022 |
| Esry Properties Ltd | Real estate | 2021 |
| Essbee Solutions Ltd | Wholesale & retail | 2019 |
| Essence Consultants Limited | Administrative & support | 2016 |
| Essence Health Ltd. | Health & social care | 2014 |
| Essence Health Solutions Limited | Health & social care | 2022 |