| Clews Property Contractors Limited | Construction | 2013 |
| Clews Tipco UK Limited | Manufacturing | 2001 |
| Clgs Communal Heating Limited | Transport & logistics | 2020 |
| CLI Windows Limited | Wholesale & retail | 2023 |
| Click 4 Pharmacy Ltd | Administrative & support | 2016 |
| Clickzio Limited | Wholesale & retail | 2025 |
| Clientstack Ltd | Professional & scientific | 2025 |
| Clifton Old Hall Developments Ltd | Construction | 2017 |
| Clima Works Ltd | Construction | 2025 |
| Climastrut Limited | Wholesale & retail | 2024 |
| Climate Care Installations Ltd | Energy | 2023 |
| Clinic ALI Estetyx Limited | Health & social care | 2025 |
| Clinic of Alternative Medicine Limited | Health & social care | 2024 |
| Clinical Accountants Limited | Real estate | 2016 |
| Clinical and Educational Healthcare Limited | Health & social care | 2015 |
| Clinical Connect Ltd | Health & social care | 2025 |
| CLK Electronics Limited | Information & communication | 2009 |
| CLN Pubs Limited | Hospitality | 2023 |
| Clocks&Barrels Ltd | Hospitality | 2019 |
| Clomwert Ltd | Wholesale & retail | 2024 |
| Clothing Solutions Limited | Real estate | 1994 |
| Cloud Connect IT Limited | Information & communication | 2014 |
| Cloud Devops Solutions Ltd | Information & communication | 2024 |
| Cloud Faux Ltd | Wholesale & retail | 2019 |
| Cloud Kickers (Holdings) Limited | Information & communication | 2016 |
| Cloud Kickers Consulting Limited | Information & communication | 2015 |
| Cloud Nine Dream Events Limited | Other services | 2007 |
| CLOUD9CAPITAL Ltd | Wholesale & retail | 2024 |
| Cloudshield IT Ltd | Information & communication | 2024 |
| CLOUDY2CLEAR Wolverhampton Limited | Construction | 2009 |
| Clover IT Contracts Ltd | Information & communication | 2005 |
| CLP Trimmings Limited | Manufacturing | 2007 |
| Club 1991 Limited | Hospitality | 2024 |
| Club Lexx Ltd | Hospitality | 2019 |
| Clutgrate Ltd | Transport & logistics | 2024 |
| CM DAN Limited | Transport & logistics | 2018 |
| CM Electrical Midlands Limited | Construction | 2020 |
| CM Hair & Beauty Supplies Limited | Wholesale & retail | 2013 |
| CM Thermo Limited | Construction | 2025 |
| CM07 Ltd | Health & social care | 2022 |
| Cmclen Ltd | Administrative & support | 2026 |
| CMF Property Services Ltd | Real estate | 2025 |
| CNC Joinery Services Limited | Manufacturing | 2012 |
| Co-Ordinators Homes Limited | Real estate | 1942 |
| Coached by the Natural Ltd | Arts & recreation | 2021 |
| Coco Nails Bloxwich Ltd | Other services | 2025 |
| Coco Tanning Lounge Limited | Other services | 2023 |
| Coconut Properties Ltd | Real estate | 2017 |
| Coeurton Ltd | Wholesale & retail | 2025 |
| Coffee & Cloth Limited | Wholesale & retail | 2017 |
| Coffeeblack Ltd | Information & communication | 2010 |
| Cofield Maintenance Limited | Construction | 2008 |
| Cofifi Estates Ltd | Hospitality | 2025 |
| Coil Products Limited | Manufacturing | 1959 |
| Coin-A-Drink Limited | Hospitality | 1966 |
| Cold Liquid Ltd | Hospitality | 2015 |
| Cole Aesthetics Clinic Ltd | Other services | 2021 |
| Colebatches Club Ltd | Hospitality | 2024 |
| Colette's Collective Ltd | Administrative & support | 2016 |
| Coliwem Ltd | Transport & logistics | 2024 |
| Collect Plus Limited | Other services | 2013 |
| Collect Property Ltd | Real estate | 2021 |
| Collect Rentals Ltd | Real estate | 2023 |
| Collectacraze Ltd | Wholesale & retail | 2025 |
| Collective GAS Ltd | Professional & scientific | 2023 |
| Collective Leisure Ltd | Real estate | 2016 |
| Collins Group International Limited | Wholesale & retail | 2000 |
| Color Tree Limited | Wholesale & retail | 2003 |
| Colormarket UK Ltd | Other services | 2024 |
| Colossus Consulting Limited | Information & communication | 2022 |
| Colour Graphics Ltd | Manufacturing | 2003 |
| Colour Rite Repairs Ltd | Wholesale & retail | 2026 |
| Colourant Management Group Ltd | Professional & scientific | 2024 |
| Colwall Conveyor Systems Limited | Professional & scientific | 2014 |
| Combined Elements Ltd | Manufacturing | 2025 |
| Combiwave Ltd | Manufacturing | 2024 |
| Comfort Beds Company Limited | Wholesale & retail | 1992 |
| Comfort Beds Property Company Limited | Real estate | 2021 |
| COMMERCE9 Ltd | Information & communication | 2024 |
| Commercial Funding Services Limited | Financial services | 2005 |
| Commercial Growth Consulting (CGC) Ltd | Professional & scientific | 2023 |
| Common-Unity Limited | Health & social care | 2009 |
| Commonwealth Judo Association | Arts & recreation | 2015 |
| Commserve Limited | Construction | 2015 |
| Communal Facilities Management Limited | Other services | 2009 |
| Communication Axiom Ltd | Information & communication | 2023 |
| Community Footprints Limited | Other services | 2015 |
| Community Footprints Service C.I.C. | Other services | 2012 |
| Community Home Companionship CIC | Health & social care | 2026 |
| Community Self Solutions CIC | Professional & scientific | 2026 |
| Community Skills and Knowledge Network CIC | Education | 2017 |
| Community Space Limited | Real estate | 2014 |
| Compare My Business Ltd | Administrative & support | 2026 |
| Compare the Storage Limited | Information & communication | 2014 |
| Compas Way Ltd | Construction | 2014 |
| Complete Civils Limited | Construction | 2024 |
| Complete Design Services Limited | Administrative & support | 2023 |
| Complete Drywall (Midlands) Limited | Construction | 2014 |
| Complete Solutions 4 U Ltd | Professional & scientific | 2005 |
| Complete Vehicle Engineering Ltd | Wholesale & retail | 2025 |