| Unity Security Solutions Limited | Administrative & support | 2018 |
| Universal Blinds & Shutters Ltd | Construction | 2021 |
| Universal Carpets & Flooring(Midlands) Ltd | Wholesale & retail | 2018 |
| Universal Healthy Minds Limited | Health & social care | 2018 |
| Universal Holistic Healings Limited | Health & social care | 2023 |
| Universal Infosys UK Ltd | Information & communication | 2023 |
| Unlock Education Limited | Information & communication | 2024 |
| Unsung Artists Limited | Arts & recreation | 2013 |
| Untold Tales Ltd | Administrative & support | 2019 |
| UP Ltd Company Ltd | Transport & logistics | 2026 |
| Upkopp Ltd | Information & communication | 2023 |
| Uplifting Healthcare Solutions Ltd | Administrative & support | 2024 |
| Uplivity Housing Ltd | Hospitality | 2025 |
| Uppal Estate Limited | Real estate | 2024 |
| Upper East 64 Ltd | Construction | 2014 |
| Upper Marlboro Properties Limited | Real estate | 2025 |
| Uptime Network Consultancy Ltd. | Construction | 2025 |
| Uptop Digital UK Ltd | Information & communication | 2025 |
| Upward (Property Estates) Limited | Real estate | 2011 |
| Upward Developments (West Midlands) Limited | Construction | 1986 |
| Urban Eats MK Ltd | Hospitality | 2024 |
| Urban Estates Limited | Real estate | 2018 |
| Urban Holiday Limited | Hospitality | 2025 |
| Urban Housing Group Ltd | Hospitality | 2026 |
| Urban Link Estates Limited | Real estate | 2007 |
| Urban Link Property Developments Ltd | Real estate | 2018 |
| Urban Property Acquisitions Ltd | Real estate | 2024 |
| Urban Smoke BBQ Ltd | Hospitality | 2025 |
| Urban Thread Collective Ltd | Manufacturing | 2025 |
| Urban Village Estates (UK) Limited | Real estate | 2011 |
| Urbanac Homes UK Ltd | Construction | 2017 |
| Urbannes Solutions Ltd | Wholesale & retail | 2026 |
| Uriah & Sons Import & Export Ltd | Transport & logistics | 2026 |
| US Nails Aldridge Ltd | Other services | 2024 |
| USE Your Initiative Ltd. | Professional & scientific | 2016 |
| Used Car Hub Ltd | Wholesale & retail | 2025 |
| Used Cardboardboxes Ltd | Administrative & support | 2022 |
| Usefultech Ltd. | Manufacturing | 2015 |
| Ustralzic Ltd | Transport & logistics | 2024 |
| Utility Compare Ltd | Professional & scientific | 2016 |
| Utility Heaven Ltd | Professional & scientific | 2021 |
| Utility Management Specialists Limited | Other services | 2018 |
| Utilityclever Ltd | Financial services | 2017 |
| Utopia Blinds and Curtains Limited | Construction | 2007 |
| Utopia Shutter Company Ltd | Manufacturing | 2016 |
| Uttle Limited | Real estate | 2017 |
| Uttoxeter Angling Association Limited(The) | Professional & scientific | 1947 |
| UV Gill Courier Ltd | Transport & logistics | 2025 |
| UVD Ltd | Administrative & support | 2016 |
| V Duta Ltd | Transport & logistics | 2026 |
| V Property Ltd | Real estate | 2024 |
| V S T Medicals Limited | Health & social care | 2013 |
| V&R Rendering EWI Limited | Construction | 2023 |
| V-Global Accountants Limited | Professional & scientific | 2021 |
| V-Tech Electronics Limited | Wholesale & retail | 2023 |
| V.F.T Solutions Ltd | Construction | 2025 |
| V8 Velocity Ltd | Wholesale & retail | 2025 |
| VAG Exclusive Ltd | Wholesale & retail | 2020 |
| Vagcar Limited | Wholesale & retail | 2008 |
| Vakrefad Ltd | Administrative & support | 2024 |
| Valbest Cleaning Solutions Ltd | Other services | 2024 |
| Valeon Building Solutions Limited | Construction | 2016 |
| Valeriameri Ltd | Transport & logistics | 2024 |
| Valeter Ltd | Wholesale & retail | 2014 |
| Valexa Limited | Construction | 2024 |
| Vali Balt 2809 Limited | Transport & logistics | 2025 |
| Valley Tissues Ltd | Wholesale & retail | 2022 |
| Valoriz Consulting Limited | Construction | 2026 |
| Valuekod Ltd | Professional & scientific | 2018 |
| Valwet Ltd | Wholesale & retail | 2026 |
| Valzol Lubricants Limited | Professional & scientific | 2004 |
| Van Loon Medical Limited | Health & social care | 2015 |
| Van Loon Property Limited | Real estate | 2022 |
| VAN1LLA Thinking Ltd | Information & communication | 2012 |
| Vanaerix Ltd | Administrative & support | 2024 |
| Vanazin Ltd | Administrative & support | 2024 |
| Vanchoice Ltd | Information & communication | 2024 |
| Vanguard Building Compliance Limited | Construction | 2024 |
| Vanguard Energy Solutions Ltd | Construction | 2026 |
| Vanilla Blue Digital Limited | Professional & scientific | 2012 |
| Vanilla Blue Limited | Wholesale & retail | 2013 |
| Vanilla Thinking Limited | Information & communication | 2003 |
| Vanjay Limited | Health & social care | 2018 |
| Vantage Construction Ltd | Construction | 2025 |
| Vantage Properties Limited | Real estate | 1992 |
| Vape and Tech Walsall Ltd | Wholesale & retail | 2024 |
| VAR Auto Ltd | Manufacturing | 2026 |
| Varachia Property Management Ltd | Households | 2022 |
| Vausages Limited | Manufacturing | 2018 |
| Vayo Consulting Limited | Professional & scientific | 2017 |
| Vayo Homes Limited | Real estate | 2024 |
| Vccp Ltd | Real estate | 2021 |
| VCK9SECURITY Limited | Administrative & support | 2021 |
| VCS Logistics Ltd | Transport & logistics | 2015 |
| VED Transportation Limited | Transport & logistics | 2018 |
| Veds (Midlands) Ltd | Other services | 2013 |
| Veenpool.Media Ltd | Information & communication | 2019 |
| Veevah Limited | Information & communication | 2017 |
| Vega Tattoo Ltd | Other services | 2018 |
| Vegetable and Fruit Shop Ltd | Wholesale & retail | 2024 |